Results 151 to 160 of about 39,976 (219)

Formative Evaluation: The TVOntario Perspective

Canadian Journal of Learning and Technology, 2009
Patricia Parsons, Anne-Marie Lemire
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Implementation and evaluation of customized artificial intelligence personal tutor (chat GPT physiology companion) for medical students in the reproduction module. [PDF]

BMC Med Educ
Elsamanoudy A, Alhazimi A, Hassanien M, Almarabheh A, Al-Aqidi S, Alwalidi R, Alrefaie Z.   +6 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

MusicAlzheimer: AI-Powered, Culturally Tailored Digital Music Therapy Prototype for Alzheimer Disease Care. [PDF]

JMIR Form Res
Yang S, Zhang DY, Zhang M, Yang H, Ma Y.
europepmc   +1 more source

Formative Evaluation of Educational Television

Canadian Journal of Learning and Technology, 2009
Jon Baggaley
doaj   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

A modular clinical thinking navigation system: an exploration in the '101 Project' diagnostics textbook reform. [PDF]

BMC Med Educ
Bi R, Zhang Y, Jiang R, Jin T, Yang J, Song L, Zhou J, Zhang H, Ye T, Zhou X, Zhan H.   +10 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Automatic Speech Recognition and Large Language Models for Multilingual Pathology Report Generation: Proof-of-Concept Study. [PDF]

JMIR Form Res
Lin KH, Chang CP, Kuo CT, Hsu CY, Hung SH, Lien CY, Lee SH, Yeh YC, Chu YC.   +8 more
europepmc   +1 more source