Results 131 to 140 of about 46,944 (265)

DMAIC-ing a Difference: Improving Formative Feedback in Clinical Clerkships. [PDF]

Clin Teach
Nestani A, Beduhn B, Tamarelli C, Ruff A.   +3 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Correction: Personalized Diabetes Treatment Support Using Large Language Models Fine-Tuned on Electronic Health Records: Development and Evaluation Study. [PDF]

JMIR Form Res
He S, Zhang Y, Li J.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Formules pédagogiques et évaluation formative : une combinaison gagnante / [PDF]

, 2015
Howe, Robert
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Criteria of teacher and students's didactic performances in psychology: the Peruvian university students' perceptions. [PDF]

Front Psychol
Bazán-Ramírez A, Capa-Luque W, Henostroza-Mota CR, Mayorga-Falcón LE, Montgomery-Urday W, Félix-Benites ED, Palomino-Miranda NA, Solano-Gutierrez J, Chauca-Calvo MH.   +8 more
europepmc   +1 more source

Apologie de l'évaluation formative [PDF]

, 2015
Aylwin, Ulric
core  

La grille de critères pour autoévaluer : norme à respecter ou outil évolutif pour progresser ?

, 2005
International audienceCette communication s'appuie sur une étude de cas de mémoires professionnels d'enseignants stagiaires, qui ont pour objet d'étudier les effets, sur des apprentissages en production d'écrits, de dispositifs impliquant des élèves de ...
Campanale, Françoise
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source