Results 51 to 60 of about 1,270,842 (242)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Daniel Senise: pintura como abrigo da imagem
Poiésis, 2018 Daniel Senise é um dos mais emblemáticos pintores da chamada “Geração 80” no Brasil. A partir da obra de Senise, este ensaio procura entender a arte egressa dos 1980 não apenas como a “volta da pintura” — o retorno conservador a um tipo de linguagem ou ...
Daniela Name
doaj +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Archivos Latinoamericanos de Nutrición, 2004 RESUMEN Las raíces y tubérculos tropicales (RTT) son alimentos básicos de la dieta de los pobladores de estas zonas; son producidos por pequeños y medianos agricultores y se les ha prestado poca atención.
Adriana Blanco-Metzler +2 more
doaj
Implementing distributed concurrent constraint execution in the CIAO system
, 1996 This paper describes the current prototype of the distributed CIAO system. It introduces the concepts of "teams" and "active modules" (or active objects), which conveniently encapsulate different types of functionalities desirable from a distributed ...
Cabeza Gras, Daniel +1 more
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Paradoxical time and providential history in Shakespeare and Bacon [PDF]
, 1999 Few of Shakespeare's tragic characters have had so many detractors as Richard II, who has been variously dismissed as a capricious tyrant, a self-absorbed poet, and a Protean dramatic force whose unpredictable actions at times threaten the structural ...
Rodríguez García, José María
core +3 more sources
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Modelo para el pronóstico financiero de siembra y comercialización de tubérculos: Caso Ñame. [PDF]
, 2015 Proyecto de Graduación (Maestría de Administración de Empresas con énfasis en Finanzas) Instituto Tecnológico De Costa Rica. Escuela de Administración de Empresas, 2015.El presente trabajo propone un modelo financiero para la predicción de rentabilidad ...
Azofeifa-Alvarado, David +2 more
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