Results 1 to 10 of about 81,581 (293)

Synthesis and bioactivities evaluation of oleanolic acid oxime ester derivatives as α-glucosidase and α-amylase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
Different oleanolic acid (OA) oxime ester derivatives (3a-3t) were designed and synthesised to develop inhibitors against α-glucosidase and α-amylase. All the synthesised OA derivatives were evaluated against α-glucosidase and α-amylase in vitro.
Xu-Yang Deng, Jun-Jie Ke, Ying-Ying Zheng, Dong-Li Li, Kun Zhang, Xi Zheng, Jing-Ying Wu, Zhuang Xiong, Pan-Pan Wu, Xue-Tao Xu   +9 more
doaj   +2 more sources

Proteinaceous α-amylase inhibitors: purification, detection methods, types and mechanisms

International Journal of Food Properties, 2021
α-Amylase is abundant in plants and animals. α-Amylase inhibitors can reduce endogenous α-amylase activity, playing an essential role in agricultural pest control, and preventing and treating human disease. In the agricultural field, α-Amylase inhibitors
He Li, Haochun Zhou, Jian Zhang, Xiaohang Fu, Zhiwei Ying, Xinqi Liu   +5 more
doaj   +2 more sources

Optimization and scale-up of α-amylase production by Aspergillus oryzae using solid-state fermentation of edible oil cakes

BMC Biotechnology, 2021
Background Amylases produced by fungi during solid-state fermentation are the most widely used commercial enzymes to meet the ever-increasing demands of the global enzyme market.
M. Balakrishnan, G. Jeevarathinam, S. Kiran Santhosh Kumar, Iniyakumar Muniraj, Sivakumar Uthandi   +4 more
doaj   +2 more sources

Enhanced extracellular expression of Bacillus stearothermophilus α-amylase in Bacillus subtilis through signal peptide optimization, chaperone overexpression and α-amylase mutant selection

Microbial Cell Factories, 2019
Background Our laboratory has constructed a Bacillus stearothermophilus α-amylase (AmyS) derivative with excellent enzymatic properties. Bacillus subtilis is generally regarded as safe and has excellent protein secretory capability, but heterologous ...
Dongbang Yao, Lingqia Su, Na Li, Jing Wu
doaj   +2 more sources

Genomic and enzymatic insights into α-amylase-producing Bacillus spizizenii strains isolated from Isfahan province, Iran. [PDF]

PLoS One
Al Sharif B, Golchini MM, Soorni A, Mehrabi R.   +3 more
europepmc   +2 more sources

New Insights into the Latest Advancement in α-Amylase Inhibitors of Plant Origin with Anti-Diabetic Effects

Plants, 2023
The rising predominance of type 2 diabetes, combined with the poor medical effects seen with commercially available anti-diabetic medications, has motivated the development of innovative treatment approaches for regulating postprandial glucose levels ...
Hamdy Kashtoh, Kwan-Hyun Baek
semanticscholar   +1 more source

Dietary Polyphenols as Natural Inhibitors of α-Amylase and α-Glucosidase

Life, 2022
It is well known that carbohydrates are the main source of calories in most diets. However, by inhibiting carbohydrases, intake of calories is reduced and weight loss is improved.
Ina Ćorković, D. Gašo-Sokač, Anita Pichler, J. Šimunović, M. Kopjar   +4 more
semanticscholar   +1 more source

Inhibition Effect and Molecular Mechanism of Tea Polyphenols on the α-Amylase

Shipin gongye ke-ji, 2022
In present study, the inhibitory effect and molecular mechanism of tea polyphenols on α-amylase were investigated. With the determination of inhibition kinetics, the inhibition of tea polyphenols on α-amylase was estimated.
Hongtu ZHANG, Weijin DONG, Nan CHEN, Qianda XU, Haoxiang GAO, Qiang HE, Weicai ZENG   +6 more
doaj   +1 more source

Immobilization of Aspergillus fumigatus α-Amylase via Adsorption onto Bentonite/Chitosan for Stability Enhancement

Emerging Science Journal, 2023
Stability enhancement attempted in this study demonstrated that significant improvement in the stability of the α-amylase isolated from Aspergillus fumigatus was achieved by immobilizing the enzyme on a bentonite/chitosan hybrid matrix using the ...
Y. Yandri, Hendri Ropingi, T. Suhartati, Bambang Irawan, S. Hadi   +4 more
semanticscholar   +1 more source

Wheat seed germination based on α-amylase activity to study promoting mechanism of Bacillus subtilis QM3 [PDF]

Journal of Seed Science, 2022
: The mechanism of promoting wheat seed germination by Bacillus subtilis has been paid great attention by many scholars. The germination rate and α-amylase activity of wheat seeds were significantly increased after germinating with Bacillus subtilis QM3 ...
Qing-ping Hu, Jing Guo, Jing-jing Liu
doaj   +1 more source