Results 131 to 140 of about 2,396,283 (252)

Μαθηματικά: Επίπεδο διδασκαλίας Α: Βιβλίο μαθητή

, 2007
Το πρώτο βιβλίο απευθύνεται σε παιδιά σχολικού επιπέδου Νηπιαγωγείου καθώς και Α΄ και Β΄ δημοτικού. Οι ενότητές του περιέχουν μαθηματικές δραστηριότητες κυρίως αριθμητικής, γεωμετρίας και επίλυσης προβλημάτων οι οποίες υποβοηθούν και συμπληρώνουν έννοιες
Κλώθου, Άννα, Κορδά, Αγγελική, Λάζου, Ευσταθία, Τριανταφυλλίδης, Τριαντάφυλλος Α., Σδρόλιας, Κωνσταντίνος Α., Νιζάμ, Αχμέτ, Πόταρη, Δέσποινα, Σακονίδης, Χαράλαμπος, Χριστάκης, Ιωάννης, Κοσμάνος, Νικόλαος   +9 more
core  

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Iso-α-acids, bitter components of beer, prevent obesity-induced cognitive decline. [PDF]

Sci Rep, 2018
Ayabe T, Ohya R, Kondo K, Ano Y.
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Iso-α-acids, Hop-Derived Bitter Components of Beer, Attenuate Age-Related Inflammation and Cognitive Decline. [PDF]

Front Aging Neurosci, 2019
Ano Y, Ohya R, Kondo K, Nakayama H.
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Polyaniline Doping by α,α-Difluoro-β-amino Acids

ACS Omega, 2019
Yuriy Noskov, Alexander Sorochinsky, Valery Kukhar, Alexander Pud   +3 more
doaj   +1 more source

Effects of iso-α-acids, the hop-derived bitter components in beer, on the MRI-based Brain Healthcare Quotient in healthy middle-aged to older adults. [PDF]

Neuropsychopharmacol Rep, 2019
Kita M, Yoshida S, Kondo K, Yamakawa Y, Ano Y.   +4 more
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Synthesis of α‑Hydroxy Fatty Acids from Fatty Acids by Intermediate α‑Chlorination with TCCA under Solvent-Free Conditions: A Way to Valorization of Waste Fat Biomasses

ACS Omega, 2021
Valentina Bertolini, Marco Pallavicini, Gaurao Tibhe, Gabriella Roda, Sebastiano Arnoldi, Laura Monguzzi, Marina Zoccola, Giovanna Di Nardo, Gianfranco Gilardi, Cristiano Bolchi   +9 more
doaj   +1 more source