Results 101 to 110 of about 732,445 (126)

PINK1-Parkin-Mediated mitophagy alleviates hepatocyte injury induced by α-amanitin

Ecotoxicology and Environmental Safety
The death cap mushroom (Amanita phalloides) is one of the most toxic fungi worldwide, with α-amanitin (α-AMA) identified as its primary lethal toxin. Mitophagy selectively eliminates damaged mitochondria via the autophagy pathway and plays a critical ...
Yang Zhao, Ziheng Zou, Peng Wu, Zehui Li, Zhijie Liu, Zhengwang Yi, Juyu Wang, Yi Wu, Weijie Qu, Bundit Tengjaroensakul, Jian Sun, Xiaolong Gu   +11 more
doaj   +1 more source

Yüksek Saflıkta Beta Amanitin Üretimi [PDF]

, 2012
Amaç: Beta amanitin nadiren bilimsel araştırmalarda kullanılmakta ve kullanımı gün geçtikçe artmaktadır. Piyasada bu ürün %90 saflıkta ticari olarak satılmaktadır. Bu araştırmada yüksek saflıkta beta amanitin üretme yöntemi tanımlanmıştır.
Kaya, Ertuğrul, Bayram, Recep, Yaykaşlı, Kürşat Oğuz, Sarıtaş, Ayhan, Karahan, Selim, Yaykaşlı, Emine   +5 more
core   +2 more sources

Comprehensive Clinical Profile of Amanita exitialis Poisoning: Integrating Toxin Detection and Autopsy Pathology

Toxins
Amanita exitialis is a lethal mushroom species found in southern China. Its amatoxins can cause acute liver injury with a high case-fatality rate. However, reports combining toxin detection in clinical specimens with autopsy pathology remain limited.
Chong-Gui Chen, Ping Xu, Ji-Pin Li, Xiao-Li Bi, Qun-Mei Yao, Cheng-Min Yu, Yan Tang, Cheng-Ye Sun, Zhi-Jun Wu, Jia-Ju Zhong, Hai-Ying Wu   +10 more
doaj   +1 more source

Poster Sessions

HemaSphere, Volume 9, Issue S1, June 2025.
wiley   +1 more source

α-AMA induced liver failure is associated with elevation of HMGB1 lactylation modification in mice

BMC Gastroenterology
Background Acute liver failure (ALF) induced by poisonous mushrooms represents the most significant threat to humans from mushroom poisoning, primarily attributable to α-amanitin (α-AMA).
Shaofang Huang, Jian Tao, Hui Xiao, Shuling Wu, Wei Ye, Shipeng Huang   +5 more
doaj   +1 more source

Production of High Purity Beta Amanitin [PDF]

, 2012
Amaç: Beta amanitin nadiren bilimsel araştırmalarda kullanılmakta ve kullanımı gün geçtikçe artmaktadır. Piyasada bu ürün %90 saflıkta ticari olarak satılmaktadır. Bu araştırmada yüksek saflıkta beta amanitin üretme yöntemi tanımlanmıştır.
Kaya, Ertuğrul, Bayram, Recep, Yaykaşlı, Kürşat Oğuz, Sarıtaş, Ayhan, Karahan, Selim, Yaykaşlı, Emine   +5 more
core   +1 more source

New in silico insights into the inhibition of RNAP II by α-amanitin and the protective effect mediated by effective antidotes [PDF]

Journal of Molecular Graphics and Modelling, 2014
Poisonous α-amanitin-containing mushrooms are responsible for the major cases of fatalities after mushroom ingestion. α-Amanitin is known to inhibit the RNA polymerase II (RNAP II), although the underlying mechanisms are not fully understood ...
Juliana Garcia, Alexandra T P Carvalho, Daniel F A R Dourado   +2 more
exaly   +2 more sources

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Mechanism and treatment of α-amanitin poisoning

Archives of Toxicology, 2022
Guobing Chen, Chen Guobing
exaly  

Rapid detection of α-amanitin and β-amanitin in rat plasma by ultra-performance liquid chromatography–tandem mass spectrometry and its application to the toxicokinetic study of Lepiota brunneoincarnata

Forensic Toxicology, 2021
Zhengsheng Mao, Youjia Yu, Yue Cao
exaly  

A Convergent Total Synthesis of the Death Cap Toxin α‐Amanitin

Angewandte Chemie - International Edition, 2020
Mary-Ann J Siegert, Roderich D Süssmuth
exaly