In vitro α-glucosidase inhibitory activity of Tamarix nilotica shoot extracts and fractions.
PLoS ONE, 2022 α-glucosidase inhibitors represent an important class of type 2 antidiabetic drugs and they act by lowering postprandial hyperglycemia. Today, only three synthetic inhibitors exist on the market, and there is a need for novel, natural and more efficient ...
Mariane Daou +5 more
doaj +5 more sources
Evaluation of α-Glucosidase Inhibitory Effect of 50% Ethanolic Standardized Extract of Orthosiphon stamineus Benth in Normal and Streptozotocin-Induced Diabetic Rats [PDF]
, 2015 In the present study, a 50% ethanolic extract of Orthosiphon stamineus was tested for its α-glucosidase inhibitory activity. In vivo assays of the extract (containing 1.02%, 3.76%, and 3.03% of 3′hydroxy-5,6,7,4′-tetramethoxyflavone, sinensetin, and ...
Ahmad, Mariam +4 more
core +6 more sources
Exploring the inhibitory effect and mechanism of 3,4,5-trihydroxybiphenyl on α-glucosidase: an integrated experimental and computational approach [PDF]
Frontiers in Pharmacology3,4,5-Trihydroxybiphenyl (THB) is a naturally occurring compound derived from Sorbus pohuashanensis, primarily reported for its antifungal activity. However, its potential to inhibit α-glucosidase remains unclear.
Ruofan Guo +15 more
doaj +2 more sources
Synthèses enzymatiques de néoglucoconjugués catalysées par l'alpha-glucosidase purifiée de la blatte Periplaneta americana (Linnaeus) [PDF]
Biotechnologie, Agronomie, Société et Environnement, 2005 Enzymatic synthesis of neoglucoconjugates by purified α-glucosidase from cockroach Periplaneta americana (Linnaeus). Cockroach Periplaneta americana (Linnaeus) contains in his digestive tract an acid (pH 5,0) and mesophile (50°C) α-glucosidase.
Kamenan A. +4 more
doaj +2 more sources
Advances in the natural α‐glucosidase inhibitors
eFood, 2023 α‐Glucosidase (AG) inhibitors, one of the classes of oral antidiabetics used to treat type 2 diabetes mellitus, delay digestion and absorption of glucose, which in turn, has a lowering effect on postprandial blood glucose and insulin levels.
Didem Şöhretoğlu +4 more
doaj +1 more source
Digital Chinese Medicine, 2021 Objective: To screen for α-glucosidase inhibitor active compounds in the total saponins of Baibiandou (Lablab Semen Album) based on UHPLC-Q-Exactive Orbitrap MS technology and to evaluate its hypoglycemic activity in vivo.
Jun Han +3 more
doaj +1 more source
Isomaltooligosaccharides Production Using α-Glucosidase Activity from Zalaria sp. Him3, a Fructooligosaccharides-Producing Yeast. [PDF]
Curr MicrobiolMatsuya H +3 more
europepmc +3 more sources
α-glucosidase inMycoplasma mycoidessubspeciescapri [PDF]
FEMS Microbiology Letters, 1988 Mycoplasma mycoides subsp. capri utilisede maltose in medium lacking serum and hence serum saccharolytic enzymes. The presence of α-glucosidase activity was demonstrated by p-nitrophenyl-α-d-glucoside hydrolysis in toluene-treated cells. Specific activities were approx.
B.J. Wadher, R.J. Miles
openaire +1 more source
β-Glucosidase from the cellulolytic system of Alternaria alternata autolyzed cultures [PDF]
FEMS Microbiology Letters, 1988 A β-glucosidase from centrifugated autolyzed cultures of Alternaria alternata has been purified 71 times by Sephadex G-200, CM-Biogel A and DEAE-Biogel A successively. The enzyme is a glycoprotein with 16% sugar and a Mr of 160 000, formed by two subunits of 60 000 and 80 000.
MarÃa Jesús MartÃnez +3 more
openaire +1 more source
BMC Chemistry, 2022 Background A series of coumarin-indole hybrids was synthesized as the new α-glucosidase inhibitors. The title hybrids were considered as α-glucosidase inhibitors because had two active pharmacophores against α-glucosidase: coumarin and indole.
Davood Rezapour Niri +9 more
doaj +1 more source