Results 91 to 100 of about 789,557 (313)
A New Vista of Opportunity in Diabetes Management: Natural Product‐Based β‐cell Preservation
Preserving functional β‐cells via natural products offers promising strategy for diabetes treatment. ABSTRACT A defining characteristic of diabetes is β‐cell failure, in which β‐cells cannot modulate insulin secretion to compensate for escalating insulin resistance, pushing forward disease development.
Yi‐San Lee +4 more
wiley +1 more source
Coumarin linked to 2-phenylbenzimidazole derivatives as potent α-glucosidase inhibitors
α-Glucosidase inhibitors have emerged as crucial agents in the management of type 2 diabetes mellitus. In the present study, a new series of coumarin-linked 2-phenylbenzimidazole derivatives 5a–m was designed, synthesized, and evaluated as anti-α ...
Mina Sadeghi Ganjeh +3 more
doaj +1 more source
Additional file 2. Circular dichroism spectrums of the wild type and mutant proteins of Bgl3A (0.5 mg/ml).
Xia, Wei +7 more
openaire +1 more source
Composite sourdough breads were developed from blends of unripe plantain, tiger nut, and fenugreek flours. Optimized formulations improved pasting stability and enhanced texture, producing softer more elastic crumbs. The enriched breads contained higher dietary fiber and bioactive compounds, and significantly reduced serum cholesterol markers ...
Mary T. Ademosun +4 more
wiley +1 more source
Bee pollen samples from China and Spain exhibited in vitro antioxidant, anti‐inflammatory, and digestive enzyme inhibitory activities due to their composition, suggesting their potential as a nutraceutical or functional ingredient to help counteract oxidative stress, chronic inflammation, and metabolic disorders.
Adriana Maite Fernández‐Fernández +9 more
wiley +1 more source
Antidesma celebicum Miq . belongs to Euphorbiaceae family has been use d as antidiabetic traditional medic ine . The aim of the research was to isolate the α Glucosidase inhibitory compound from ethanol extract of Antidesma celebicum l eaves. The isolation have been done using column chromatography silica gel 60 and the structure was determinated base ...
Fajar Utami Novi, Elya Berna, Katrin .
openaire +1 more source
α-Glucosidase inhibitors isolated from medicinal plants
Objectiveα-Glucosidase inhibitors can be used as a new class of antidiabetic drug. By competitively inhibiting glycosidase activity, these inhibitors help to prevent the fast breakdown of sugars and thereby control the blood sugar level.
Feng, Fajin +4 more
core +1 more source
Pectin, a versatile natural polymer, is extracted through conventional and emerging green extraction methods, offering multifunctional bioactive properties useful in food, pharmaceutical, and environmental applications. ABSTRACT Pectin, a molecular tapestry woven from diverse polysaccharides, holds a pivotal role across food, pharmaceutical, and ...
Afra Anika Rafique +3 more
wiley +1 more source
Cloning and Expression of Marine α-Glucosidase and Its Preparation of High Purity Panose
Panose is iso-malto-oligosaccharide contained α-1,6 glycosidic bonds, and α-glucosidase is the key enzyme to produce panose. In this study, the α-glucosidase gene in deep-sea hydrothermal vents thermophilic archaea Thermococcus siculi HJ21 was ...
Yiqun YU +6 more
doaj +1 more source

