Results 81 to 90 of about 789,557 (313)

α-Glucosidase and α-Amylase Inhibitory Compounds from three African Medicinal Plants: An Enzyme Inhibition Kinetics Approach

Natural Product Communications, 2017
The quest to find new lead compounds with anti-diabetic effects via the inhibition of α-glucosidase and α-amylase had led us to conduct bioassay guided isolation of three African medicinal plants which resulted in the identification of bicyclo[2.2.0 ...
Mohammed Auwal Ibrahim, James Dama Habila, Neil Anthony Koorbanally, Md. Shahidul Islam   +3 more
doaj   +1 more source

MOESM4 of The structural and functional contributions of β-glucosidase-producing microbial communities to cellulose degradation in composting

, 2018
Additional file 4. Additional Materials and Methods.
Zang, Xiangyun, Liu, Meiting, Fan, Yihong, Xu, Jie, Xu, Xiuhong, Li, Hongtao   +5 more
openaire   +1 more source

β-Glucosidase activity from the thermophilic fungusScytalidium thermophilumis stimulated by glucose and xylose [PDF]

FEMS Microbiology Letters, 2004
An inducible mycelial beta-glucosidase from Scytalidum thermophilum was characterized. The enzyme exhibited a pI of 6.5, a carbohydrate content of 15%, and an apparent molecular mass of about 40 kDa. Optima of temperature and pH were 60 degrees C and 6.5, respectively.
Fabiana Fonseca, Zanoelo, Maria de Lourdes Teixeira de Moraes, Polizeli, Héctor Francisco, Terenzi, João Atílio, Jorge   +3 more
openaire   +2 more sources

Stage‐Dependent Metabolic Reprogramming Drives a Self‐Organizing Microbial Network During Shanxi Aged Vinegar

Food Bioengineering, EarlyView.
Metabolic shifts from growth to stress adaptation in Shanxi aged vinegar fermentation link flavor maturation and microbial cooperation, and Lactobacillus and Acetobacter form a self‐organizing metabolic network through division of labor. ABSTRACT Acetic acid fermentation (AAF) is a vital stage in the production of Shanxi aged vinegar (SAV), during ...
Yanfang Wu, Jing Liu, Dantong Liu, Menglei Xia, Jia Song, Yu Zheng, Min Wang   +6 more
wiley   +1 more source

Isatin-based ibuprofen and mefenamic acid Schiff base derivatives as dual inhibitors against urease and α–glucosidase: In vitro, in silico and cytotoxicity studies

Journal of Saudi Chemical Society
α-Glucosidase and urease inhibitors have emerged as crucial for developing therapeutic drugs targeting diabetes and gastrointestinal disorders. This study reports on new series of ibuprofen and mefenamic acid Schiff base derivatives incorporating isatin ...
Saima Daud, Obaid‐ur‐Rahman Abid, Malik Saadullah, M. Fakhar-e-Alam, Simone Carradori, Asma Sardar, Basit Niaz, M. Atif, Susi Zara, Muhammad Rashad   +9 more
doaj   +1 more source

Analysis of α-glucosidase genes using Blastx.

, 2013
Analysis of α-glucosidase genes using Blastx.
Ligia Souza Ferreira (370709), Gonçalo Apolinário de Souza-Filho (370713), Olga Lima Tavares Machado (370720), Carlos Peres Silva (370718), José Roberto da Silva (370708), Viviane Veiga do Nascimento (370719), Marilvia Dansa-Petretski (370723), Flávia Borges Mury (370707), Jayme Augusto de Souza-Neto (370715), Paulo Eduardo Martins Ribolla (370717), Marília Amorim Berbert-Molina (370721), Beatriz dos Santos Ferreira (370711)   +11 more
core   +1 more source

Molecular dynamics simulations reveal the inhibitory mechanism of Withanolide A against α-glucosidase and α-amylase

, 2023
Diabetes mellitus (DM) is a global chronic disease characterized by hyperglycemia and insulin resistance. The unsavory severe gastrointestinal side-effects of synthetic drugs to regulate hyperglycemia have warranted the search for alternative treatments ...
Mohd Hayrie, Mohd Hatta, Oyewusi, Habeebat Adekilekun, Safi, Sher Zaman, Kalaivani, Batumalaie, Wu, Yuan Seng *, Roswanira, Abdul Wahab   +5 more
core   +1 more source

Fermentation‐Induced Modulation of Polyphenolic Contents and Medicinal Activities in Annona squamosa Seeds

Food Chemistry International, EarlyView.
The study compared the medicinal activities of polyphenols from fermented and unfermented seeds of Annona squamosa. The polyphenols were extracted and subjected to standard analysis. The major phenolic components of the fermented polyphenols and the unfermented polyphenols were found to be 4‐hydroxybenzoic and 4‐hydroxyphenylacetic acid, respectively ...
Shola Hezekiah Awojide, Abayomi Gideon Adeyemo, Christianah Dare, Oluseye Oladapo Abiona, Adedayo Olubunmi Adeboye, Omolara Oladipo‐Olalekan, Aminat Adebola Adeyemo, Yemisi Elizabeth Asibor, Emmanuel Oluwafemi Adeniyi, Bunmi Regina Bankole, Ezekiel Olumide Fadunmade   +10 more
wiley   +1 more source

MOESM1 of The structural and functional contributions of β-glucosidase-producing microbial communities to cellulose degradation in composting

, 2018
Additional file 1: Figure S1. Differences in the abundance and expression of GH1B and GH3E genes in the natural compost and the inoculated compost.
Zang, Xiangyun, Liu, Meiting, Fan, Yihong, Xu, Jie, Xu, Xiuhong, Li, Hongtao   +5 more
openaire   +1 more source

Kinetics of Hypoglycemic α-Glucosidase Inhibitory Protein

, 2018
The activity of a-glucosidase enzyme (EC 3.2.1.20) was inhibited by 40.3% by an extracellular inhibitory protein which isolated from the culture filtrate of Aspergillus brasiliensis ATCC-16404. The maximum activity of this protein and fungal mycelial dry
Fahad A. Al-Dhabaan, Fahad Al-Dhabaan
core   +1 more source