Results 111 to 120 of about 1,551,967 (375)

Glycogenosis type II (acid maltase deficiency) [PDF]

, 1995
Glycogen storage disease type II (GSD II/glycogenosis type II/Pompe's disease/acid maltase deficiency) is caused by the deficiency of lysosomal α-glucosidase resulting in lysosomal accumulation of glycogen.
Bijvoet, A.G.A. (Agnes), Diggelen, O.P. (Otto) van, Hermans, M.M.P. (Monique), Kleijer, W.J. (Wim), Kroos, M.A. (Marian), Ploeg, A.T. (Ans) van der, Reuser, A.J.J. (Arnold), Verbeet, M.Ph. (Martin)   +7 more
core   +1 more source

Exploring the Anti‐Diabetic Potential of Anthocyanins: From Biochemical Pathways to Human Trials

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Diabetes mellitus (DM) is a global health challenge with increasing prevalence rates, particularly in low‐ and middle‐income countries. Anthocyanins (ACs) are potential bioactive compounds found in various fruits and vegetables, attracting the attention of researchers due to their possible role in managing diabetes and its complications ...
Lakshay Panchal, Sangeeta Yadav, Akash Kumar, Tanbeer Kaur, Yashna Bawa, Sarvesh Rustagi, Rahul Mehra   +6 more
wiley   +1 more source

Effect of different drying methods and solvent ratios on biological activities of Phyllanthus acidus extracts [PDF]

, 2017
The main purpose of this study was to evaluate the antioxidant and α-glucosidase inhibitory activities of Phyllanthus acidus. The P. acidus fruits were dried using three different methods, namely oven (OD), air (AD) and freeze (FD) dryings and extracted ...
A. G., Siti Zulaikha, Abas, Faridah, Khoo, L. W., Lee, S. Y., Leong, S. W., Mediani, Ahmed   +5 more
core  

New records of potent in-vitro antidiabetic properties of Dalbergia tonkinensis heartwood and the bioactivity-guided isolation of active compounds [PDF]

, 2018
[[abstract]]Alpha-glucosidase inhibitory activity has been commonly used for the evaluation of antidiabetic property in vitro. The aim of this study is to investigate and characterize Dalbergia tonkinensis as a potential source of antidiabetic compounds.
Aguiree, DeMelo, Fujita, Gerstein, McCue, Nguyen, Nguyen, Nguyen, Ninh, Ninh, Robert, Srivastava, Vasudeva   +12 more
core   +1 more source

Antidiabetic Potential of Ligands from NEIST_PMIB_06, Bacterium Associated with Hawaijar (Fermented Soy Food): Insight from in Vitro and in Silico Studies

ChemFoodChem, EarlyView.
ABSTRACT In this study, a bacterium (NEIST_PMIB_06) was isolated from Hawaijar, a fermented soy food from Manipur, Northeast India. The bacterium was inoculated and incubated to isolate bioactive compounds. Liquid‐liquid extraction was performed to obtain extracts (cell‐free and cell‐based), and their efficacy was evaluated.
A Ibeyaima, Hiranmoy Barman, Prasenjit Manna   +2 more
wiley   +1 more source

Isatin-based ibuprofen and mefenamic acid Schiff base derivatives as dual inhibitors against urease and α–glucosidase: In vitro, in silico and cytotoxicity studies

Journal of Saudi Chemical Society
α-Glucosidase and urease inhibitors have emerged as crucial for developing therapeutic drugs targeting diabetes and gastrointestinal disorders. This study reports on new series of ibuprofen and mefenamic acid Schiff base derivatives incorporating isatin ...
Saima Daud, Obaid‐ur‐Rahman Abid, Malik Saadullah, M. Fakhar-e-Alam, Simone Carradori, Asma Sardar, Basit Niaz, M. Atif, Susi Zara, Muhammad Rashad   +9 more
doaj   +1 more source

MOESM6 of Production of a high-efficiency cellulase complex via β-glucosidase engineering in Penicillium oxalicum

, 2016
Additional file 6: Table S1. Primers used in this study.
Guangshan Yao, Ruimei Wu, Qinbiao Kan, Liwei Gao, Liu, Meng, Piao Yang, Du, Jian, Zhonghai Li, Yinbo Qu   +8 more
openaire   +1 more source

Synthesis and Glycosidase Inhibition Studies of Novel Exoglycals Targeting GH3 Family Enzymes: Insights from Comparative Analysis with Macrolide Antibiotics

Chemistry – A European Journal, EarlyView.
A series of structurally diverse exoglycals was synthesized using a modified Julia‐olefination approach from sugar‐derived precursors. These glycosidase transition‐state mimics were further diversified via CuAAC chemistry to yield triazole‐conjugated analogues.
Elisa Ospanow, Oscar L. Alferez, David L. Jakeman   +2 more
wiley   +1 more source

Health promoting potential of herbal teas and tinctures from Artemisia campestris subsp maritima: from traditional remedies to prospective products [PDF]

, 2018
This work explored the biotechnological potential of the medicinal halophyte Artemisia campestris subsp. maritima (dune wormwood) as a source of health promoting commodities.
A Akrout, A Alam, A Atia, A Buhmann, A Djeridane, A Lopes, AA Jahid, AP Rauter, AS Ribeiro, B Boulanouar, B Saad, CG Pereira, CG Pereira, D Paepe De, DA Viegas, DR Nogueira, F Shahidi, H Akkari, H Riedel, H Sebai, I Dib, I Jallali, JF Sanz, JG Gruenwald, JMJ Vasconcelos, KM Valant-Vetschera, L Barreira, L Custódio, M Karamać, M Saoudi, M Sefi, MJ Rodrigues, MJ Rodrigues, MJ Rodrigues, MP Kähkönen, MTH Khan, N Balasundram, P Pohl, R Ksouri, RW Pero, S Kumar, S Saeidnia, SK Panigrahy, T Oki, T-S Chang, V Sindhi, W Megdiche-Ksouri, YI Kwon, Z Ghlissi   +48 more
core   +2 more sources

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source