Results 231 to 240 of about 42,943 (266)

Rational design and synthesis of new acetamide-indole-benzo[d]imidazole-carboxylic acid hybrids as dual PTP1B/α-glucosidase inhibitors. [PDF]

RSC Adv
Dastyafteh N, Ghafouri SN, Mollazadeh M, Motamedi Shakib N, Halimi M, Hosseini S, Mojtabavi S, Faramarzi MA, Larijani B, Amanlou M, Mohammadi-Khanaposhtani M, Mahdavi M.   +11 more
europepmc   +1 more source

Is scaffold hopping possible in machine learning using the electronic-structure-informatics (ESI) descriptor set? an application to natural-product-based drug discovery of α-glucosidase inhibitors. [PDF]

J Cheminform
Tateishi Y, Sugimoto M.
europepmc   +1 more source

Sustainable Synthesis of 1,2-Disubstituted Benzimidazoles as Promising α-Glucosidase Inhibitors: In Vitro and In Silico Evaluation. [PDF]

Pharmaceuticals (Basel)
Tocco G, Laus A, Manis C, Caboni P, Fais A, Era B.   +5 more
europepmc   +1 more source

Patterns and Trends of Glucose‐Lowering Therapy in Alzheimer's Disease and Related Dementias

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7592-7596, August 2026.
Huilin Tang, Bingyu Zhang, Yiwen Lu, Ying Lu, Anastassia Amaro, Yuan Lu, David A. Wolk, Yong Chen   +7 more
wiley   +1 more source

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A Computational Comparative study of α-Glucosidase enzyme Divergence

Journal of Applied Bioinformatics & Computational Biology, 2015
A Computational Comparative study of α-Glucosidase enzyme Divergence α-Glucosidase (α-Gls) enzymes have a crucial role in digestion of carbohydrates and biosynthesis of glycoproteins. Theses enzymes hydrolyze terminal glycosidic bonds and release α-glucose from the substrate chain. They are found in prokaryotic cells, plants and mammalian tissues such
Mohammad Hossein Mehraban, Younes Ghasemi   +1 more
openaire   +1 more source

Performance of β-Glucosidase produced by Ganoderma lucidum using Waste Substrate as Carbon Source

Journal of Biochemistry, Microbiology and Biotechnology, 2013
Oil palm empty fruit bunch (OPEFB) was used for the production of β-glucosidase by Ganoderma lucidum in submerged fermentation. The activity of β-glucosidase had shown an improvement by going from pH 4 to 6 and declined towards alkaline pH. The highest activity (47.75 U/mL) was obtained at pH 6 with 2.0 mm size of substrate’s particle.
Nur Haziqah Aniyah Salihan, Arbakariya Ariff, Mohd Rafein Zakaria, Suraini Abd-Aziz, Md Noor Bd Wahab, Helmi Wasoh   +5 more
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POTENTIAL INHIBITORS OF α-GLUCOSIDASE AND α-AMYLASE ENZYMES FROM LOCALLY AVAIALABLE FRUIT WASTES BY SOLID STATE FERMENTATION

Chemical and Natural Resources Engineering Journal (Formally known as Biological and Natural Resources Engineering Journal), 2019
ABSTRACT: A   therapeutic   approach   for   treating   diabetes   is   to   decrease   the   post-prandial hyperglycaemia. This is done by retarding the absorption of glucose through the inhibition of the carbohydrate hydrolyzing enzymes, α-amylase and α-glucosidase, in the digestive tract.
ANUMSIMA AHMAD BARKAT, Parveen Jamal, AZLIN SUHAIDA AZMI, IBRAHIM ALI NOORBACHA, DACHYAR ARBAIN, ZULKARNAIN MOHAMED IDRIS   +5 more
openaire   +1 more source

ANTIDIABETIC ACTIVITY TEST OF BITTER GOURD EXTRACT (Momordica charantia) AS AN INHIBITOR OF α - GLUCOSIDASE ENZYME BY IN SILICO

2022
ABSTRACTDiabetes mellitus (DM) is a metabolic disorder that interferes with the metabolism of carbohydrates, fats, and proteins. This study aims to determine the types of bioactive compounds contained in bitter melon extract and to analyze interaction of targeted compounds against the α -glucosidase enzyme using the in silico approach.
Wowor, Kezya, Bodhi, Widdhi, Datu, Olvie, Windah, Axl   +3 more
openaire   +1 more source

Solvent Effect on Phenolic Compounds Extraction, Antioxidant Capacities and Α-Amylase and Α-Glucosidase Inhibition of Clematis flammula and Periploca angustifolia

Journal of Pharmaceutics & Drug Delivery Research, 2016
Solvent Effect on Phenolic Compounds Extraction, Antioxidant Capacities and Α-Amylase and Α-Glucosidase Inhibition of Clematis flammula and Periploca angustifolia Abstract Phytochemicals are extensively found at different levels in many medicinal plants.
Khaled Athmouni, Taheni Belghith
openaire   +1 more source