Results 281 to 290 of about 1,798,291 (314)

Chromone-based benzohydrazide derivatives as potential α-glucosidase inhibitor: Synthesis, biological evaluation and molecular docking study.

Bioorganic chemistry (Print), 2022
In order to find new α-glucosidase inhibitors with high efficiency and low toxicity, novel chromone-based benzohydrazide derivatives 6a-6s were synthesized and characterized through 1H NMR, 13C NMR, and HRMS. All the new synthesized compounds were tested
Meiyan Fan, Wei-Qiang Yang, Zhiyun Peng, Yan He, Guangcheng Wang   +4 more
semanticscholar   +1 more source

POTENTIAL INHIBITORS OF α-GLUCOSIDASE AND α-AMYLASE ENZYMES FROM LOCALLY AVAIALABLE FRUIT WASTES BY SOLID STATE FERMENTATION

Chemical and Natural Resources Engineering Journal (Formally known as Biological and Natural Resources Engineering Journal), 2019
ABSTRACT: A   therapeutic   approach   for   treating   diabetes   is   to   decrease   the   post-prandial hyperglycaemia. This is done by retarding the absorption of glucose through the inhibition of the carbohydrate hydrolyzing enzymes, α-amylase and α-glucosidase, in the digestive tract.
ANUMSIMA AHMAD BARKAT, Parveen Jamal, AZLIN SUHAIDA AZMI, IBRAHIM ALI NOORBACHA, DACHYAR ARBAIN, ZULKARNAIN MOHAMED IDRIS   +5 more
openaire   +1 more source

ANTIDIABETIC ACTIVITY TEST OF BITTER GOURD EXTRACT (Momordica charantia) AS AN INHIBITOR OF α - GLUCOSIDASE ENZYME BY IN SILICO

2022
ABSTRACTDiabetes mellitus (DM) is a metabolic disorder that interferes with the metabolism of carbohydrates, fats, and proteins. This study aims to determine the types of bioactive compounds contained in bitter melon extract and to analyze interaction of targeted compounds against the α -glucosidase enzyme using the in silico approach.
Wowor, Kezya, Bodhi, Widdhi, Datu, Olvie, Windah, Axl   +3 more
openaire   +1 more source

Solvent Effect on Phenolic Compounds Extraction, Antioxidant Capacities and Α-Amylase and Α-Glucosidase Inhibition of Clematis flammula and Periploca angustifolia

Journal of Pharmaceutics & Drug Delivery Research, 2016
Solvent Effect on Phenolic Compounds Extraction, Antioxidant Capacities and Α-Amylase and Α-Glucosidase Inhibition of Clematis flammula and Periploca angustifolia Abstract Phytochemicals are extensively found at different levels in many medicinal plants.
Khaled Athmouni, Taheni Belghith
openaire   +1 more source

Development of inhibitors against lipase and α-glucosidase from derivatives of monascus pigment

FEMS Microbiology Letters, 2007
New derivatives of monascus pigment were produced during Monascus fermentation by the addition of unnatural amino acids, and the inhibitory activities of the derivatives against diet-related lipase and alpha-glucosidase were tested. Derivatives with penicillamine (H-Pen), cyclohexylalanine (H-Cha), butylglycine (L-t-Bg), and norleucine (H-Nle) showed ...
Jong Hoon, Kim, Hyun Jung, Kim, Hae Woong, Park, Sung Hun, Youn, Duck-Young, Choi, Chul Soo, Shin   +5 more
openaire   +2 more sources

The role of olive β-glucosidase in shaping the phenolic profile of virgin olive oil

Food Research International, 2012
The main objective of this work was to investigate the biochemical factors directly affecting the phenolic profile of virgin olive oil (VOO) such as the content of phenolic glycosides and the β-glucosidase activity present in the olive fruit. The phenolic compositions of VOO from two olive cultivars, Arbequina and Picual, were studied throughout the ...
Romero-Segura, Carmen, García-Rodríguez, Rosa, Sánchez-Ortiz, Araceli, Sanz, Carlos, Pérez Rubio, Ana Gracia   +4 more
openaire   +2 more sources

Induction and preliminary characterization of intracellular β-glucosidases from a cellulolyticStreptomycesstrain

FEMS Microbiology Letters, 1995
The cellulolytic actinomycete Streptomyces sp. QM-B814 possess an intracellular beta-glucosidase system which is induced by cellobiose and carboxymethylcellulose. Maximal beta-glucosidase activity was attained 8-10 h after inducer addition to exponential phase growing cultures. The induction is depressed in the presence of glucose.
J A, Pérez-Pons, X, Rebordosa, E, Querol   +2 more
openaire   +2 more sources

Structural requirements of flavonoids for the selective inhibition of α-amylase versus α-glucosidase.

Food Chemistry, 2021
Jongbin Lim, M. Ferruzzi, B. Hamaker
semanticscholar   +1 more source

Thiazolidine-2,4-dione derivatives as potential α-glucosidase inhibitors: Synthesis, inhibitory activity, binding interaction and hypoglycemic activity.

Bioorganic chemistry (Print)
Mengyue Li, Jinping Sun, Bingwen Liang, Xiaofeng Min, Jinhui Hu, Rihui Wu, Xuetao Xu   +6 more
semanticscholar   +1 more source

Inhibition mechanism of diacylated anthocyanins from purple sweet potato (Ipomoea batatas L.) against α-amylase and α-glucosidase.

Food Chemistry, 2021
Yang Yang, Jiu‐liang Zhang, L. Shen, Lan-jie Feng, Qing Zhou   +4 more
semanticscholar   +1 more source