Results 271 to 280 of about 1,798,291 (314)

Chemical structure and inhibition on α-glucosidase of polysaccharides from corn silk by fractional precipitation.

Carbohydrate Polymers, 2021
Aimed to explore different corn silk polysaccharide (CSP) fractions derived by ethanol precipitation on the physicochemical properties and biological activities, four fractions (CSP20, CSP40, CSP60, and CSP80) were obtained.
Yanan Jia, Zihan Xue, Yajie Wang, Yangpeng Lu, Ruilin Li, Nannan Li, Qirou Wang, Min Zhang, Min Zhang, Haixia Chen   +9 more
semanticscholar   +1 more source

Inhibition mechanism of ferulic acid against α-amylase and α-glucosidase.

Food Chemistry, 2020
The inhibitory mechanisms of ferulic acid against α-amylase and α-glucosidase were investigated by enzyme kinetic analysis, circular dichroism (CD), Fourier-transform infrared (FT-IR) spectroscopy, fluorescence quenching and molecular docking.
Yuxue Zheng, Jinhu Tian, Wenhan Yang, Shiguo Chen, Donghong Liu, Haitian Fang, Huiling Zhang, Xingqian Ye   +7 more
semanticscholar   +1 more source

Performance of β-Glucosidase produced by Ganoderma lucidum using Waste Substrate as Carbon Source

Journal of Biochemistry, Microbiology and Biotechnology, 2013
Oil palm empty fruit bunch (OPEFB) was used for the production of β-glucosidase by Ganoderma lucidum in submerged fermentation. The activity of β-glucosidase had shown an improvement by going from pH 4 to 6 and declined towards alkaline pH. The highest activity (47.75 U/mL) was obtained at pH 6 with 2.0 mm size of substrate’s particle.
Nur Haziqah Aniyah Salihan, Arbakariya Ariff, Mohd Rafein Zakaria, Suraini Abd-Aziz, Md Noor Bd Wahab, Helmi Wasoh   +5 more
openaire   +1 more source

Recent Advances of α-Glucosidase Inhibitors: A Comprehensive Review.

Current Topics in Medicinal Chemistry, 2022
BACKGROUND Diabetes mellitus (DM) is a critical health issue prevailing in nearly half a billion people worldwide. It is one of the most threatening metabolic diseases. Type 2 DM is caused due to insulin resistance and accounts for 90% of diabetes cases.
Ahsas Goyal, N. Agrawal, Manisha Sharma, Shikha Singh   +3 more
semanticscholar   +1 more source

Novel Bis-Schiff's base derivatives of 4-nitroacetophenone as potent α-glucosidase agents: Design, synthesis and in silico approach.

Bioorganic chemistry (Print), 2022
Bis-Schiff's base derivatives of 4-nitroacetophenone (1-18) were synthesized in good yields by reacting hydrazone of 4-nitroacetophenone with substituted aldehydes and ketones with catalytic amount of acetic acid.
A. Alam, Mumtaz Ali, A. Latif, N. Rehman, Samina Saher, Zainab, Faryal, Ajmal Khan, S. Ullah, Obaid Ullah, S. Halim, F. Sani, A. Al‐Harrasi, Manzoor Ahmad   +13 more
semanticscholar   +1 more source

The inhibitory mechanism of chlorogenic acid and its acylated derivatives on α-amylase and α-glucosidase.

Food Chemistry, 2021
Due to the poor lipophilicity of chlorogenic acid (CA), five CA derivatives (C2-CA, C4-CA, C6-CA, C8-CA, and C12-CA) with different lipophilicities were synthesized using acylation catalyzed by lipase in present study.
Shang-Sheng Wang, Yue Li, Dejian Huang, Shang-wei Chen, Yong-mei Xia, Song Zhu   +5 more
semanticscholar   +1 more source

In vitro and in vivo inhibitory effect of anthocyanin-rich bilberry extract on α-glucosidase and α-amylase

, 2021
The inhibition of glycosidase activity is regarded as an effective treatment for diabetes mellitus. Bilberry (Vaccinium myrtillus L.) fruit has a high content of anthocyanins with various biological activities.
Yanglin Ji, Dong Liu, Yan Jin, Juan Zhao, Jiang Zhao, Heyu Li, Liwei Li, Huan Zhang, Hao Wang   +8 more
semanticscholar   +1 more source

Extraction, identification, and molecular mechanisms of α-glucosidase inhibitory peptides from defatted Antarctic krill (Euphausia superba) powder hydrolysates.

International Journal of Biological Macromolecules
The objective of this study was to explore the potential of Antarctic krill-derived peptides as α-glucosidase inhibitors for the treatment of type 2 diabetes.
Kewei Zheng, Yuanyuan Wu, Qingfei Dai, Xiaojun Yan, Yu Liu, Di Sun, Zhongjie Yu, Shuoqi Jiang, Qingbao Ma, Wei Jiang   +9 more
semanticscholar   +1 more source

The antioxidant activities, inhibitory effects, kinetics, and mechanisms of artocarpin and α-mangostin on α-glucosidase and α-amylase.

International Journal of Biological Macromolecules, 2022
This study investigated the antioxidant activities, inhibitory activities and the interaction mechanisms of artocarpin and α-mangostin on α-amylase and α-glucosidase.
Qirou Wang, Ruilin Li, Nannan Li, Yanan Jia, Yajie Wang, Yue Chen, P. Panichayupakaranant, Haixia Chen   +7 more
semanticscholar   +1 more source

Metabolite profiling, antioxidant and α-glucosidase inhibitory activities of buckwheat processed by solid-state fermentation with Eurotium cristatum YL-1.

Food Research International, 2021
Buckwheat was processed by solid-state fermentation (SSF) with the probiotic fungal strain Eurotium cristatum YL-1. The effects of SSF on the phytochemical content, as well as the antioxidant and α-glucosidase inhibitory activities, on buckwheat were ...
Yu Xiao, Xing Wu, Xin-Tong Yao, Yulian Chen, Chi-Tang Ho, Cheng-hui He, Zongjun Li, Yuanliang Wang   +7 more
semanticscholar   +1 more source