Results 261 to 270 of about 1,798,291 (314)

Studies on the inhibition of α-glucosidase by biflavonoids and their interaction mechanisms.

Food Chemistry, 2023
Biflavonoids are a kind of polyphenol compounds with numerous biological functions. However, the potential inhibitory activities of biflavonoids on α-glucosidase are yet unknown.
Huan Li, Jichen Yang, Mengfan Wang, Xiang-Yu Ma, Xin Peng   +4 more
semanticscholar   +1 more source

Fruit, vegetables, and mushrooms for the preparation of extracts with α-amylase and α-glucosidase inhibition properties: A review.

Food Chemistry, 2021
The inhibition of the α-amylase and α-glucosidase activity facilitates the maintenance of circulating glucose levels by decreasing the rate of blood sugar absorption.
Konstantinos Papoutsis, Jinyuan Zhang, M. Bowyer, N. Brunton, E. Gibney, J. Lyng   +5 more
semanticscholar   +1 more source

Identification of 1,3,4-oxadiazolyl-containing β-carboline derivatives as novel α-glucosidase inhibitors with antidiabetic activity.

European journal of medicinal chemistry, 2023
In this study, we designed and synthesized a novel class of 1,3,4-oxadiazolyl-containing β-carboline derivatives, i.e., compounds f1∼f35 as potential α-glucosidase inhibitors.
Di Xiao, Li Lu, Bingwen Liang, Zhuang Xiong, Xuetao Xu, Wen-Hua Chen   +5 more
semanticscholar   +1 more source

Comparison of the generation of α-glucosidase inhibitory peptides derived from prolamins of raw and cooked foxtail millet: In vitro activity, de novo sequencing, and in silico docking.

Food Chemistry, 2023
Foxtail millet prolamin has been demonstrated to have anti-diabetic effects. In this study, we compared the generation of anti-α-glucosidase peptides derived from prolamins of raw and cooked foxtail millet (PRFM and PCFM).
Yongxia Fu, Zhenyu Liu, Han Wang, Fan Zhang, Shang Guo, Q. Shen   +5 more
semanticscholar   +1 more source

A Computational Comparative study of α-Glucosidase enzyme Divergence

Journal of Applied Bioinformatics & Computational Biology, 2015
A Computational Comparative study of α-Glucosidase enzyme Divergence α-Glucosidase (α-Gls) enzymes have a crucial role in digestion of carbohydrates and biosynthesis of glycoproteins. Theses enzymes hydrolyze terminal glycosidic bonds and release α-glucose from the substrate chain. They are found in prokaryotic cells, plants and mammalian tissues such
Mohammad Hossein Mehraban, Younes Ghasemi   +1 more
openaire   +1 more source

Flavonoids as potential agents in the management of type 2 diabetes through the modulation of α-amylase and α-glucosidase activity: a review

Critical reviews in food science and nutrition, 2021
Type 2 diabetes (T2D) is one of the most prevalent metabolic diseases worldwide and is characterized by increased postprandial hyperglycemia (PPHG). α-Amylase and α-glucosidase inhibitors have been shown to slow the release of glucose from starch and ...
C. Proença, D. Ribeiro, M. Freitas, E. Fernandes   +3 more
semanticscholar   +1 more source

Novel bioactive peptides from ginkgo biloba seed protein and evaluation of their α-glucosidase inhibition activity.

Food Chemistry, 2022
The inhibition of α-glucosidase activity has been recognized as an effective approach for treating type 2 diabetes mellitus (T2DM). In recent years, much emphasis has been placed on identifying peptides with α-glucosidase inhibitory activity and ...
Xiang Wang, Yejun Deng, Pujun Xie, Lujie Liu, Caihong Zhang, Jiang Cheng, Yang Zhang, Y. Liu, Lixin Huang, Jianxin Jiang   +9 more
semanticscholar   +1 more source

Effects of hydroxylation at C3' on the B ring and diglycosylation at C3 on the C ring on flavonols inhibition of α-glucosidase activity.

Food Chemistry, 2022
The structure-activity relationship and inhibitory mechanism of flavonols on α-glucosidase were studied by inhibition kinetics, multispectral study, and molecular docking.
Yajuan Qin, Xiaoai Chen, Fei Xu, Chunhe Gu, Kexue Zhu, Yanjun Zhang, Gang Wu, P. Wang, L. Tan   +8 more
semanticscholar   +1 more source

Lumi-HOF@Tb as Probes for Multiple Ratiometric Fluorescence and Chemiluminescence Sensing of α-Glucosidase.

Analytical Chemistry, 2022
The innovative assembly of luminescent hydrogen-bonded organic frameworks (HOFs) into multifunctional optical sensors is of great significance for developing advanced materials.
Haiyan Li, Shangqing Zhang, Mingli Chen, Jianhua Wang   +3 more
semanticscholar   +1 more source

Comparative study of inhibition mechanisms of structurally different flavonoid compounds on α-glucosidase and synergistic effect with acarbose.

Food Chemistry, 2021
Flavonoid compounds have anti-diabetic activity, which can control blood glucose levels by inhibiting α-glucosidase activity. In this paper, the inhibition mechanisms between four flavonoid compounds and α-glucosidase were studied by multispectroscopic ...
Jichen Yang, Xiaoli Wang, Chuanying Zhang, Lun Ma, Tao Wei, Yajing Zhao, Xin Peng   +6 more
semanticscholar   +1 more source