Results 251 to 260 of about 976,226 (308)

First Report on the Phytochemical and Pharmacological Properties of Hedysarum yilmazunalii

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Hedysarum yilmazunalii was collected from Erzincan, Türkiye. The leaf, stem, and root parts were then used for methanolic extraction. The extracts were analyzed for their phytochemical composition by LC–MS/MS and tested for antioxidant, enzyme inhibitory, and antiproliferative activities.
Etem Osma, Tuğçe Varol, Samed Şimşek, Sevgi Altın, Mustafa Abdullah Yılmaz, Ali Aydın, Müjgan Elveren, Ali Kandemir   +7 more
wiley   +1 more source

α-Glucosidase Inhibitory Activity of Tsuan-Kan Tea in Different Solid-State Aging Models: Phytochemical Biotransformation, Volatile Profile, and Molecular Docking. [PDF]

Foods
Yang YC, Chiang YC, Chiang PY.
europepmc   +1 more source

Investigation of In Vitro α‐Amylase Inhibitory, Antioxidant, Phytochemical Profiling, Molecular Docking, and Swiss ADME Analysis of Magnolia zotictla

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Phytochemical profiling was determined via HPLC and GC–MS analysis. In HPLC analysis, five compounds were identified, while five compounds were identified through GC–MS. The plant extract exhibited good antioxidant efficacy in the DPPH assay, highlighting its capacity to neutralize free radicals. The extract has IC5₀ value of 123.8 µg/mL, while that of
Muhammad Zahoor, Usra Shah, Marwa Bibi, Adnan Khan, Haseena, Amal Alotaibi   +5 more
wiley   +1 more source

Discovery of 4-aminochalcone-based dual α-glucosidase and aldose reductase inhibitors: <i>in vitro</i>, <i>in vivo</i>, and <i>in silico</i> studies. [PDF]

RSC Adv
Mughal EU, Naeem N, Bayrak S, Kılınç N, Shakoor B, Zaki MEA, Fathalla M, Gomha SM, Sadiq A, Almaz Z.   +9 more
europepmc   +1 more source

Phenolic Profiling and Bioactivity Evaluation of Stachys aleurites Extracts: LC–ESI–MS/MS Characterization, Antioxidant Capacity, and Enzyme Inhibitory Potential

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Solvent polarity shapes the phytochemical and bioactivity profile of Stachys aleurites. Methanol extraction enriches phenolics, especially verbascoside and chlorogenic acid, and enhances antioxidant and enzyme inhibitory activities, whereas the aqueous extract shows selective metal‐chelating and BChE inhibitory potential. ABSTRACT Natural products rich
Fatma Ozlem Kargin Solmaz, Cengiz Sarikurkcu, Bektaş Tepe   +2 more
wiley   +1 more source

Sources of Polyphenols with Potential α-Glucosidase-Inhibitory Activities from Thai Local Edible Plants: In Vitro and Network Pharmacology Approaches. [PDF]

Plants (Basel)
Puthongking P, Ratha J, Siriparu P, Subhan M, Panyatip P, Sripadung P, Padumanonda T, Tadtong S, Lim V, Sungthong B.   +9 more
europepmc   +1 more source

Computational and Comparative In Vitro Evaluation of GC–MS Profiled Cannabis sativa Inflorescence Extracts’ Metabolites on Selected Diabetes Therapeutic Targets

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Cannabis sativa inflorescence extracts demonstrate promising antidiabetic potential through enzyme inhibition, antioxidant activity, and molecular docking. The hexane extract exhibits the strongest bioactivity, while key cannabinoids show high affinity for diabetes‐related targets, highlighting the plant as a promising source of novel antidiabetic ...
Rosa M. Chinheya, Viviane L. N. Ngoungoure, Ibeabuchi Ali, Kolawole Olofinsan, Tsebo Jim, Francine Tankeu, Motlalepula G. Matsabisa   +6 more
wiley   +1 more source

Integrating Peptidomics, Network Pharmacology, Molecular Docking, and In Vitro α-Glucosidase Inhibition Assays to Explore the Hypoglycemic Activity and Action Mechanisms of Chinese Yam Peptides. [PDF]

Foods
Ma HK, Li XY, Shen L, Ji HF.
europepmc   +1 more source

Design, Synthesis, Molecular Dynamics, and In Vitro Evaluation of Isatin‐Based Quinazoline Derivatives as Potential Antidiabetic Agents

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
A series of substituted indolo[2,1‐b]quinazoline‐6,12‐diones (SJ1‐SJ8) has been studied for their possible α‐amylase inhibition property as an antidiabetic lead compound. The most potent inhibitory activity among the tested derivatives was showed by SJ2 (IC50 = 18.49 ± 0.06 µM), similar to the reference drug acarbose (IC50 = 16.26 ± 0.02 µM).
Sahil Jaidka, Ankush Kumar, Christopher Basumatary, Thakur Gurjeet Singh, Rohit Bhatia   +4 more
wiley   +1 more source

Identification of α-glucosidase inhibitory phytochemicals from Erythrina crista-galli using combined experimental and computational methods. [PDF]

BMC Chem
Anggraeni HR, Akili AWR, Ikhsan MH, Hardianto A, Latip J, Herlina T.   +5 more
europepmc   +1 more source