Results 171 to 180 of about 2,753,652 (191)

Comparison of the generation of α-glucosidase inhibitory peptides derived from prolamins of raw and cooked foxtail millet: In vitro activity, de novo sequencing, and in silico docking.

Food Chemistry, 2023
Foxtail millet prolamin has been demonstrated to have anti-diabetic effects. In this study, we compared the generation of anti-α-glucosidase peptides derived from prolamins of raw and cooked foxtail millet (PRFM and PCFM).
Yongxia Fu, Zhenyu Liu, Han Wang, Fan Zhang, Shang Guo, Q. Shen   +5 more
semanticscholar   +1 more source

Screening and Evaluation of Novel α-Glucosidase Inhibitory Peptides from Ginkgo biloba Seed Cake Based on Molecular Docking Combined with Molecular Dynamics Simulation.

Journal of Agricultural and Food Chemistry, 2023
Food-derived α-glucosidase inhibitory peptides have gained significant interest in treating type 2 diabetes mellitus (T2DM) owing to their favorable safety profiles.
Xiang Wang, Yejun Deng, Yang Zhang, Caihong Zhang, Lujie Liu, Y. Liu, Jianxin Jiang, Pujun Xie, Lixin Huang   +8 more
semanticscholar   +1 more source

Flavonoids as potential agents in the management of type 2 diabetes through the modulation of α-amylase and α-glucosidase activity: a review

Critical reviews in food science and nutrition, 2021
Type 2 diabetes (T2D) is one of the most prevalent metabolic diseases worldwide and is characterized by increased postprandial hyperglycemia (PPHG). α-Amylase and α-glucosidase inhibitors have been shown to slow the release of glucose from starch and ...
C. Proença, D. Ribeiro, M. Freitas, E. Fernandes   +3 more
semanticscholar   +1 more source

Effects of hydroxylation at C3' on the B ring and diglycosylation at C3 on the C ring on flavonols inhibition of α-glucosidase activity.

Food Chemistry, 2022
The structure-activity relationship and inhibitory mechanism of flavonols on α-glucosidase were studied by inhibition kinetics, multispectral study, and molecular docking.
Yajuan Qin, Xiaoai Chen, Fei Xu, Chunhe Gu, Kexue Zhu, Yan-Jun Zhang, Gang Wu, P. Wang, L. Tan   +8 more
semanticscholar   +1 more source

Characterization of selenized polysaccharides from Ribes nigrum L. and its inhibitory effects on α-amylase and α-glucosidase.

Carbohydrate Polymers, 2021
The polysaccharide from Ribes nigrum L. (RCP) was modified by nitric acid-sodium selenite method. After purification by Sepharose-6B, high purity native (PRCP) and three selenized polysaccharides (PRSPs) with different selenium contents were obtained ...
Meimei Zhao, Jing-Wen Bai, Xueying Bu, Yuanxue Yin, Li-Bo Wang, Yu Yang, Ya-Qin Xu   +6 more
semanticscholar   +1 more source

Novel bioactive peptides from ginkgo biloba seed protein and evaluation of their α-glucosidase inhibition activity.

Food Chemistry, 2022
The inhibition of α-glucosidase activity has been recognized as an effective approach for treating type 2 diabetes mellitus (T2DM). In recent years, much emphasis has been placed on identifying peptides with α-glucosidase inhibitory activity and ...
Xiang Wang, Yejun Deng, Pujun Xie, Lujie Liu, Caihong Zhang, Jiang Cheng, Yang Zhang, Y. Liu, Lixin Huang, Jian-Xin Jiang   +9 more
semanticscholar   +1 more source

Comparative study of inhibition mechanisms of structurally different flavonoid compounds on α-glucosidase and synergistic effect with acarbose.

Food Chemistry, 2021
Flavonoid compounds have anti-diabetic activity, which can control blood glucose levels by inhibiting α-glucosidase activity. In this paper, the inhibition mechanisms between four flavonoid compounds and α-glucosidase were studied by multispectroscopic ...
Jichen Yang, Xiaoli Wang, Chuanying Zhang, Lun Ma, Tao Wei, Yajing Zhao, Xin Peng   +6 more
semanticscholar   +1 more source

Lumi-HOF@Tb as Probes for Multiple Ratiometric Fluorescence and Chemiluminescence Sensing of α-Glucosidase.

Analytical Chemistry, 2022
The innovative assembly of luminescent hydrogen-bonded organic frameworks (HOFs) into multifunctional optical sensors is of great significance for developing advanced materials.
Hai-Yan Li, Shang-Qing Zhang, Mingli Chen, Jian-Hua Wang   +3 more
semanticscholar   +1 more source

Inhibition mechanism of ferulic acid against α-amylase and α-glucosidase.

Food Chemistry, 2020
The inhibitory mechanisms of ferulic acid against α-amylase and α-glucosidase were investigated by enzyme kinetic analysis, circular dichroism (CD), Fourier-transform infrared (FT-IR) spectroscopy, fluorescence quenching and molecular docking.
Yuxue Zheng, Jinhu Tian, Wenhan Yang, Shi-Guo Chen, Dong-Hong Liu, Haitian Fang, Huiling Zhang, Xing-Qian Ye   +7 more
semanticscholar   +1 more source

Chemical structure and inhibition on α-glucosidase of polysaccharides from corn silk by fractional precipitation.

Carbohydrate Polymers, 2021
Aimed to explore different corn silk polysaccharide (CSP) fractions derived by ethanol precipitation on the physicochemical properties and biological activities, four fractions (CSP20, CSP40, CSP60, and CSP80) were obtained.
Yanan Jia, Zihan Xue, Yajie Wang, Yangpeng Lu, Ruilin Li, Nannan Li, Qirou Wang, Min Zhang, Haixia Chen   +8 more
semanticscholar   +1 more source