Results 81 to 90 of about 1,551,967 (375)

Evaluation of cannabidiol’s inhibitory effect on alpha-glucosidase and its stability in simulated gastric and intestinal fluids

open access: yesJournal of Cannabis Research, 2021
Objective Cannabidiol (CBD) has been reported to have anti-diabetic effects in pre-clinical and clinical studies but its inhibitory effects on α-glucosidase, a carbohydrate hydrolyzing enzyme, remain unknown. Herein, we evaluated CBD’s inhibitory effects
Hang Ma   +3 more
doaj   +1 more source

Binding Interaction of Betulinic Acid to α-Glucosidase and Its Alleviation on Postprandial Hyperglycemia

open access: yesMolecules, 2022
Inhibiting the intestinal α-glucosidase can effectively control postprandial hyperglycemia for type 2 diabetes mellitus (T2DM) treatment. In the present study, we reported the binding interaction of betulinic acid (BA), a pentacyclic triterpene widely ...
Shaodan Chen   +8 more
doaj   +1 more source

Antioxidant and α-glucosidase inhibitory activities of the leaf and stem of selected traditional medicinal plants [PDF]

open access: yes, 2014
The study was aimed to determine the antioxidant and α-glucosidase inhibition activities of the stem and leaf of five different traditional medicinal plants. The studied plants exhibited varied antioxidant and α-glucosidase inhibition activities.
A. H., Nur Ashikin   +4 more
core  

The effect of sulfide on -glucosidases: implications for starch degradation in anaerobic bioreactors [PDF]

open access: yes, 2007
Membrane associated α-glucosidase activity was investigated in a methanogenic bioreactor (MR) and a biosulfidogenic bioreactor (SR). Temperature and pH optima studies showed temperature optima of 50 °C and pH optima of 8.0 for the α-glucosidases from ...
Togo, C A, Wutor, V C
core   +2 more sources

Cyanoacetohydrazide linked to 1,2,3-triazole derivatives: a new class of α-glucosidase inhibitors

open access: yesScientific Reports, 2022
In this work, a novel series of cyanoacetohydrazide linked to 1,2,3-triazoles (9a–n) were designed and synthesized to be evaluated for their anti-α-glucosidase activity, focusing on the fact that α-glucosidase inhibitors have played a significant role in
Aida Iraji   +5 more
semanticscholar   +1 more source

Microenvironment Modulation‐Based Nanomaterial‐Loaded Hydrogel Dressings for Diabetic Foot Ulcers: Research Progress and Future Perspectives

open access: yesAdvanced Materials Interfaces, EarlyView.
xx xx. ABSTRACT Diabetic foot ulcer (DFU) is a chronic complication of diabetes, primarily caused by hyperglycemia, peripheral vascular disease, and neuropathy. Characterized by persistent hyperglycemia, impaired perfusion, inflammation, and infection, DFUs pose significant challenges to healing and are associated with high morbidity and amputation ...
Tang Yuqing   +5 more
wiley   +1 more source

MOESM1 of Directed evolution of a fungal β-glucosidase in Saccharomyces cerevisiae

open access: yes, 2016
Additional file 1. Table S1. Primers used in this study.
Larue, Kane   +2 more
openaire   +1 more source

ISOLATION OF Α-GLUCOSIDASE INHIBITORY ACTIVE COMPOUNDS FROM ETHANOL EXTRACT OF KAYU TUAH (ANTIDESMA CELEBICUM MIQ.) LEAVES

open access: yesInternational Research Journal of Pharmacy, 2015
Antidesma celebicum Miq . belongs to Euphorbiaceae family has been use d as antidiabetic traditional medic ine . The aim of the research was to isolate the α Glucosidase inhibitory compound from ethanol extract of Antidesma celebicum l eaves. The isolation have been done using column chromatography silica gel 60 and the structure was determinated base ...
Fajar Utami Novi, Elya Berna, Katrin .
openaire   +1 more source

Flavonoids and its derivatives from Callistephus chinensis flowers and their inhibitory activities against alpha-glucosidase [PDF]

open access: yes, 2013
Inhibitors of carbohydrate-hydrolysing enzymes play an important role for the treatment of diabetes. One of the therapeutic methods for decreasing of postprandial hyperglycemia is to retard absorption of glucose by the inhibition of carbohydrate ...
Bi, Xiuli   +5 more
core  

Influence of preparation procedures on the phenolic content, antioxidant and antidiabetic activities of green and black teas [PDF]

open access: yes, 2019
The influence of common tea preparation procedures (temperature, infusion time, consumption time interval and tea bag/loose-leaf) and the type of water used, on the total phenolic content (TPC), the radical scavenging activity and the alpha-glucosidase ...
Almeida, Tânia Santos de   +6 more
core   +3 more sources

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