Results 171 to 180 of about 33,464 (260)

Comparative effects of superheated steam and hot air roasting on the in vitro phospholipase A2 inhibitory activity and polyphenol composition of cocoa beans

Journal of the Science of Food and Agriculture, Volume 106, Issue 5, Page 3200-3207, 30 March 2026.
Abstract Background Cocoa, derived from Theobroma cacao, is a popular food ingredient used to produce chocolate. Cocoa is rich in polyphenols and human and laboratory model studies have indicated that cocoa and chocolate can mitigate chronic inflammatory conditions.
Sawali Navare, Bethany H. Lam, Misha T. Kwasniewski, Ramaswamy Anantheswaran, Joshua D. Lambert   +4 more
wiley   +1 more source

Design, eco-friendly synthesis, and molecular docking studies of isatin hybrids as promising therapeutic agents (anticancer, anticholinesterase inhibitor, α-glucosidase inhibitor, and anti-MRSA). [PDF]

RSC Adv
Seliem IA.
europepmc   +1 more source

Quinic Acid and Synthetic Derivatives in Medicinal Chemistry

ChemMedChem, Volume 21, Issue 5, 13 March 2026.
Quinic acid and its derivatives are gaining recognition as versatile scaffolds in drug discovery. This review explores their emerging roles in inflammation, infection, cancer, and metabolic disorders, highlighting recent advances that position them beyond chlorogenic acids as promising platforms for therapeutic innovation. Quinic acid (QA) is a natural
Iago C. Vogel, Manuel J. Verganista, Nuno R. Candeias   +2 more
wiley   +1 more source

Liquidambaric acid as a non-competitive α-glucosidase inhibitor: multi-level evidence from enzyme kinetics, molecular docking, molecular dynamics simulations, and a <i>Drosophila</i> hyperglycaemic model. [PDF]

J Enzyme Inhib Med Chem
Jia L, Liu Y, Fu B, Tian Y, Meng X.
europepmc   +1 more source

Microenvironment Modulation‐Based Nanomaterial‐Loaded Hydrogel Dressings for Diabetic Foot Ulcers: Research Progress and Future Perspectives

Advanced Materials Interfaces, Volume 13, Issue 5, 4 March 2026.
ABSTRACT Diabetic foot ulcer (DFU) is a chronic complication of diabetes, primarily caused by hyperglycemia, peripheral vascular disease, and neuropathy. Characterized by persistent hyperglycemia, impaired perfusion, inflammation, and infection, DFUs pose significant challenges to healing and are associated with high morbidity and amputation rates ...
Tang Yuqing, Chen Hong, Fan Weijing, Huang Renyan, You Yang, Liu Guobin   +5 more
wiley   +1 more source

<i>In vivo</i> anti-diabetic and anti-lipidemic evaluations of an excellent synthetic α-glucosidase inhibitor with dihydropyrano[3,2-c]quinoline skeleton. [PDF]

J Diabetes Metab Disord
Mohammadi-Khanaposhtani M, Bakhtiari N, Bandarian F, Larijani B, Mahdavi M, Najafzadehvarzi H.   +5 more
europepmc   +1 more source

Molecular modeling approach in design of new scaffold of <b>α</b>-glucosidase inhibitor as antidiabetic drug. [PDF]

Biochem Biophys Rep
Amini F, Abbas KI, Ghasemi JB.
europepmc   +1 more source

Chemical Constituents of Taxodium mucronatum (Cupressaceae) and Some of Its Endophytic Fungi, and Their In Silico and In Vitro Evaluations as SARS‐CoV‐2 Inhibitors and as Cytotoxic Agents

Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.
Abietanes, pimaranes and cycloartanes were characterized from different plant tissues of Taxodium mucronatum. Curvularins, mycophenolic acids and ergosterol were isolated from some fungal endophytes. The isolated compounds were in silico and in vitro evaluated as antiviral and cytotoxic agents.
Nadia Mendoza, Olivia Pérez‐Valera, Antonio Nieto‐Camacho, María Teresa Ramírez‐Apan, Marcela Guadalupe Téllez‐Martínez, Eleazar M. Escamilla‐Silva, Guillermo Delgado   +6 more
wiley   +1 more source

Severe Acute Interstitial Nephritis Induced by α-glucosidase Inhibitor Miglitol in an Elderly Patient with Type 2 Diabetic Nephropathy. [PDF]

Intern Med
Ono K, Masuda T, Ono Y, Hishida E, Yoshizawa H, Imai T, Satonaka H, Akimoto T, Nagata D.   +8 more
europepmc   +1 more source

Pneumatosis Cystoides Intestinalis Mimicking Perforation in a Patient With Gastric Signet Ring Cell Carcinoma: A Case Report

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Pneumatosis cystoides intestinalis (PCI) poses a diagnostic challenge by radiographically mimicking surgical emergencies like perforation. This case highlights that while PCI itself may be benign, the decision for exploration must weigh the risk of missing a life‐threatening condition or a coincident malignancy.
Yongshuai Lin, Weimin Wu, Xin Zhao, Jun Wang, Juan Yang   +4 more
wiley   +1 more source