Results 161 to 170 of about 18,318 (211)

Efficacy and safety of switching to iGlarLixi from premixed insulin therapy in patients with type 2 diabetes: A real‐world experience

Diabetic Medicine, Volume 43, Issue 7, July 2026.
Abstract Aims Fixed‐ratio combinations such as iGlarLixi are recommended over premixed insulin as first‐line injectable therapy for type 2 diabetes mellitus (T2DM), yet real‐world evidence on transitions from premix to iGlarLixi remains limited. This study aimed to evaluate the efficacy and safety of switching from premixed insulin to iGlarLixi in a ...
Chun‐Jui Huang, Shun‐Jie Yang, Cheng‐Pin Cheng, Chun‐Hsing Lin, Ya‐Chun Lee, Harn‐Shen Chen   +5 more
wiley   +1 more source

A systematic review and meta‐analysis of the relative benefit of dual versus single oral hypoglycaemic therapy following diagnosis with type 2 diabetes (T2D)

Diabetic Medicine, Volume 43, Issue 7, July 2026.
Abstract Introduction Achieving and sustaining target glycated haemoglobin (HbA1c) levels is fundamental in the management of type 2 diabetes (T2D). We here aimed to assess whether initial dual oral therapy outperforms monotherapy in reaching glycaemic targets in patients with treatment‐naive or early‐stage T2D.
Mairead Kelly, Sushant Saluja, Hugh Logan Ellis, Sarah Jamil, Martin B. Whyte, Adrian Heald   +5 more
wiley   +1 more source

Impact of Simulated Risk Factor Management on Cardiovascular Disease and Costs in Type 2 Diabetes Using the ABC Model

Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5670-5683, July 2026.
ABSTRACT Aims We evaluated the impact of scenario‐based multifactorial control on the 3‐year incidence of fatal/non‐fatal cardiovascular disease (CVD) and associated healthcare costs in Asian patients with type 2 diabetes (T2D). Materials and Methods We applied the validated ‘ABC’ model to simulate the 3‐year impact of attaining multiple treatment ...
Lee‐Ling Lim, Eric S. H. Lau, Juliana N. M. Lui, Linong Ji, A. G. Unnikrishnan, Sirinart Sirinvaravong, Siew‐Pheng Chan, Soo Lim, Andrea O. Y. Luk, Juliana C. N. Chan   +9 more
wiley   +1 more source

Molecular Basis for the Divergent Inhibition of α-Amylase and α-Glucosidase by Phenolic Acids: The Critical Role of Hydroxyl Substitution. [PDF]

Foods
Yang S, Li Y, Han W, Cao W, Hu Z, Zhu Z, Li M, Feng J, Zhang J.   +8 more
europepmc   +1 more source

Bifidobacterium bifidum G9‐1 Intake Improves Gastrointestinal Symptoms in Type 2 Diabetes Mellitus: An Open‐Label, Randomized Controlled Trial (Binary STAR Study)

Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5952-5967, July 2026.
ABSTRACT Aims To evaluate the effects of probiotics Bifidobacterium bifidum G9‐1 (BBG9‐1) on gastrointestinal symptoms in patients with Type 2 diabetes mellitus (T2DM) with diarrhoea or constipation. Materials and Methods In a 12‐week open‐label randomised controlled trial, 100 participants were randomized 1:1 to a control or BBG9‐1 group, with 12 mg ...
Genki Kobayashi, Yoshitaka Hashimoto, Tomoyuki Matsuyama, Noriyuki Kitagawa, Saori Majima, Takafumi Senmaru, Emi Ushigome, Hiroshi Okada, Naoko Nakanishi, Masahide Hamaguchi, Michiaki Fukui   +10 more
wiley   +1 more source

Butyrolactone-I, an efficient α-glucosidase inhibitor, improves type 2 diabetes with potent TNF-α-lowering properties through modulating gut microbiota in db/db mice.

FASEB J, 2019
Wu W, Liu L, Zhu H, Sun Y, Wu Y, Liao H, Gui Y, Li L, Liu L, Sun F, Lin H.   +10 more
europepmc   +1 more source

Analysis of the add-on effect of α-glucosidase inhibitor, acarbose in insulin therapy: A pilot study. [PDF]

Biomed Rep, 2016
Li FF, Fu LY, Xu XH, Su XF, Wu JD, Ye L, Ma JH.   +6 more
europepmc   +1 more source

Long‐Term Cultivation of Perennial Energy Crops Enhance Ecosystem Multifunctionality on Marginal Red Soil Without Trade‐Offs

GCB Bioenergy, Volume 18, Issue 7, July 2026.
Switchgrass (SG) and Miscanthus (MS) boost ecosystem multifunctionality in marginal soils. Strong synergies, not trade‐offs, exist among ecosystem services under SG and MS. MS surpasses SG in provisioning and supporting services for higher multifunctionality. MS is ideal for maximizing multifunctionality, carbon sequestration, and stability.
Yini Wu (伍旖旎), Yi Xu (许依), Tongcheng Fu (傅童成), Meng Li (李蒙), Moritz von Cossel, Grant Campbell, Pete Smith, Yasir Iqbal, Zili Yi (易自力), Shuai Xue (薛帅)   +9 more
wiley   +1 more source

Hydrazone-schiff base derivatives of 4-(tert-butyl)benzoic acid as potent enzyme inhibitors: In vitro α-amylase, α-glucosidase, tyrosinase inhibition and computational studies. [PDF]

PLoS One
Zghab I, Ahmad S, Ahmad I, Alam A, Mulk S, Aziz Z, Kamal M, Zouidi F, Alharbi AS, Elhenawy AA, Khan M.   +10 more
europepmc   +1 more source

Prefecture‐Level Prehospital Glucose Administration for Hypoglycemia and Diabetologist Density Among Older Adults in Japan: A Nationwide Ecological Study

Geriatrics &Gerontology International, Volume 26, Issue 7, July 2026.
Among older adults in Japan, higher diabetologist density was associated with lower rates of hypoglycemic events recognized by Emergency Medical Services (EMS) requiring prehospital glucose administration, despite higher insulin prescribing. These findings support improved access to certified diabetologists and stronger diabetologist–primary care ...
Tomoya Saika, Yuki Kado, Michiko Yamazaki, Tohru Takebe, Masaya Sakamoto, Atsushi Nakagomi   +5 more
wiley   +1 more source