Darier disease—A review highlighting new insights from the Darier Disease International Task Force
This review provides a global, clinically focused overview of DD, detailing cutaneous and extracutaneous manifestations, disease classification and severity scoring. It emphasizes early recognition, multidisciplinary management and practical guidance for dermatologists to apply evidence‐based care in diverse skin phototypes. Abstract Darier disease (DD)
Sofia Labbouz +49 more
wiley +1 more source
New semisynthetic α-glucosidase inhibitor from a doubly-chemically engineered extract. [PDF]
Osella MI +3 more
europepmc +1 more source
ABSTRACT Objective Although concerns have been raised that glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) may increase the risk of bowel obstruction or ileus, evidence remains inconclusive. In this context of uncertainty, we examined the frequency and determinants of GLP‐1RA discontinuation after hospitalization for bowel obstruction/ileus ...
Yuichiro Matsuo +3 more
wiley +1 more source
Design, eco-friendly synthesis, and molecular docking studies of isatin hybrids as promising therapeutic agents (anticancer, anticholinesterase inhibitor, α-glucosidase inhibitor, and anti-MRSA). [PDF]
Seliem IA.
europepmc +1 more source
Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families
ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor +4 more
wiley +1 more source
Liquidambaric acid as a non-competitive α-glucosidase inhibitor: multi-level evidence from enzyme kinetics, molecular docking, molecular dynamics simulations, and a <i>Drosophila</i> hyperglycaemic model. [PDF]
Jia L, Liu Y, Fu B, Tian Y, Meng X.
europepmc +1 more source
Abstract The aim of this systematic review and meta‐analysis was to evaluate comprehensively the therapeutic potential of Abelmoschus esculentus (okra) supplementation across the diabetes spectrum of key metabolic risk factors. A search was conducted in PubMed, Scopus, Web of Science, EMBASE and the Cochrane Library, up to 23 July 2025, to identify ...
Ali Jafari +7 more
wiley +1 more source
<i>In vivo</i> anti-diabetic and anti-lipidemic evaluations of an excellent synthetic α-glucosidase inhibitor with dihydropyrano[3,2-c]quinoline skeleton. [PDF]
Mohammadi-Khanaposhtani M +5 more
europepmc +1 more source
Bioactive Compounds and Cytotoxicity of Seed and Leaf Oils of Moringa oleifera
Among the practical applications of the oils described in this study, their use as an ingredient in food stands out, as well as the potential for developing bioactive materials for packaging, conferring antioxidant and antimicrobial properties. Seed and leaf oils from Moringa oleifera exhibit functional properties of industrial interest and bioactive ...
Emanuela de Lima Viana +12 more
wiley +1 more source
Molecular modeling approach in design of new scaffold of <b>α</b>-glucosidase inhibitor as antidiabetic drug. [PDF]
Amini F, Abbas KI, Ghasemi JB.
europepmc +1 more source

