Results 211 to 220 of about 33,378 (259)

Diversity, Function and Activity of DNA Viruses in the Qiangyong Proglacial Lake Sediment, the Tibetan Plateau

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
This study identified DNA viruses from Qiangyong proglacial lake sediments on the Tibetan Plateau, revealing a highly diverse and previously uncharacterized viral community. These viruses influence microbial community structure and function by infecting key nutrient‐transforming taxa and encoding auxiliary metabolic genes that modulate host metabolism.
Yang Zhao, Meiling Feng, Hongfei Chi, Keshao Liu, Rong Wen, Weizhen Zhang, Pengfei Liu   +6 more
wiley   +1 more source

Computational-experimental integration identifies potent carbohydrate-hydrolyzing enzyme inhibitors from Nardostachys jatamansi: molecular docking, dynamics and pharmacokinetic predictions. [PDF]

Front Pharmacol
Iqbal MJ, Malik I, Bernal G, Salas-Burgos AM, Salazar LA.   +4 more
europepmc   +1 more source

Sodium glucose co‐transporter 2 inhibitors versus dipeptidyl peptidase‐4 inhibitors and the risk of ventricular arrhythmia among patients with type 2 diabetes: A population‐based cohort study

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 935-945, February 2026.
Abstract Aims To determine whether sodium glucose co‐transporter 2 inhibitors (SGLT2i) use, compared with dipeptidyl peptidase‐4 inhibitors (DPP4i) use, is associated with the risk of ventricular arrhythmias (VA) among patients with type 2 diabetes. Materials and Methods We conducted a population‐based cohort study using a prevalent new‐user design and
Wang‐Choi Tang, Pauline Reynier, Antonios Douros, Oriana H. Y. Yu, Robert W. Platt, Kristian B. Filion   +5 more
wiley   +1 more source

Rational design and synthesis of new acetamide-indole-benzo[d]imidazole-carboxylic acid hybrids as dual PTP1B/α-glucosidase inhibitors. [PDF]

RSC Adv
Dastyafteh N, Ghafouri SN, Mollazadeh M, Motamedi Shakib N, Halimi M, Hosseini S, Mojtabavi S, Faramarzi MA, Larijani B, Amanlou M, Mohammadi-Khanaposhtani M, Mahdavi M.   +11 more
europepmc   +1 more source

Safety and effectiveness of tirzepatide during Ramadan fasting: Real‐world evidence from patients with type 2 diabetes in Bangladesh

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1508-1516, February 2026.
Abstract Aims Ramadan fasting poses challenges for patients with type 2 diabetes mellitus (T2DM) due to increased risks of hypoglycemia and metabolic fluctuations. Tirzepatide, a dual GIP/GLP‐1 receptor agonist, has shown marked efficacy in glycemic control and weight reduction.
Muhammad Hafizur Rahman, Shahjada Selim, Faria Afsana, Md. Azizul Hoque, M. Saifuddin, Md. Shah Alam, Mirza Sharifuzzaman, Mohmmad Abdul Hannan, Md. Nazmul Hasan, A. B. M. Kamrul‐Hasan, Marufa Mustari, Afsar Ahammed   +11 more
wiley   +1 more source

EAN 2024 Guideline on the Diagnostic Approach to Oligo/Asymptomatic HyperCKemia

European Journal of Neurology, Volume 33, Issue 2, February 2026.
ABSTRACT Background Recent epidemiological studies on the general population reveal that up to 1.3% have oligo/asymptomatic hyperCKemia. Objective This guideline aims to provide updated, evidence‐based recommendations on investigating persons older than 18 years.
T. Kyriakides, K. Aleksovska, C. Angelini, Z. Argov, K. G. Claeys, M. de Visser, M. FIlosto, I. Jovanovic, A. Kostera‐Pruszczyk, M. J. Molnar, S. Sacconi, J. Schaefer, G. Siciliano, J. J. Vilchez, B. Schoser, A. Toscano   +15 more
wiley   +1 more source

Exploring Small-Molecule Inhibitors of Glucosidase II: Advances, Challenges, and Therapeutic Potential in Cancer and Viral Infection. [PDF]

Int J Mol Sci
Oo TZM, Wuttiin Y, Choocheep K, Kumsaiyai W, Bunpo P, Cressey R.   +5 more
europepmc   +1 more source

Blood Pressure‐Lowering Effect of SGLT2 Inhibitors in Patients Without Antihypertensive Treatment: A Real‐World Data Analysis

The Journal of Clinical Hypertension, Volume 28, Issue 2, February 2026.
ABSTRACT Sodium‐glucose co‐transporter 2 (SGLT2) inhibitors have demonstrated blood pressure (BP)‐lowering effects; however, most studies included patients taking antihypertensive medications. Using real‐world Japanese data, we assessed factors associated with SGLT2 inhibitor‐mediated BP reduction in patients not taking antihypertensive therapy.
Reina Ito, Michihiro Satoh, Hideaki Hashimoto, Hiroki Nobayashi, Seiya Izumi, Maya Toyama, Yutaro Iwabe, Yuya Suzuki, Takuo Hirose, Shingo Nakayama, Takahisa Murakami, Masato Sasaki, Hirohito Metoki   +12 more
wiley   +1 more source

Lower glycemic status was associated with pancreatic cancer risk in prediabetes, but not in diabetes: A nationwide cohort study

Journal of Diabetes Investigation, Volume 17, Issue 2, Page 338-346, February 2026.
In a nationwide Korean cohort of nearly 3 million adults, higher fasting blood glucose within the prediabetic range—but not glycemic control among people with diabetes—was associated with increased pancreatic cancer risk, highlighting the importance of optimal glucose control in nondiabetic populations.
Dong‐Hoe Koo, Jin‐Hyung Jung, Kyungdo Han, Cheol‐Young Park   +3 more
wiley   +1 more source

Molecular Docking and Dynamics Simulations Reveal the Antidiabetic Potential of a Novel Fucoxanthin Derivative from <i>Chnoospora minima</i>. [PDF]

Mar Drugs
Sigera S, Theekshana KD, Dinanja SG, Eranga P, Karunathilake N, Abeywardhana S, Weerasinghe L, Senapathi T, Peiris DC.   +8 more
europepmc   +1 more source