Results 51 to 60 of about 33,378 (259)

Antidiabetic and antioxidant properties of Ficus deltoidea fruit extracts and fractions [PDF]

, 2013
BACKGROUND: Diabetes is a serious metabolic disorder affecting the metabolism of carbohydrate, protein and fat. A number of studies have shown that diabetes mellitus is associated with oxidative stress, leading to an increased production of reactive ...
Azlina Abdul Aziz, Hasni Misbah, Norhaniza Aminudin   +2 more
core   +1 more source

A New Era for Using Natural Pigments: The Case of the C50 Carotenoid Called Bacterioruberin

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Haloarchaea are extremophilic microorganisms belonging to the Archaea domain that require high salt concentrations to live, thus inhabiting ecosystems like salty ponds, salty marshes, or extremely salty lagoons. They are more abundant and widely distributed worldwide than initially expected.
Micaela Giani, Elena Valdés, José María Miralles‐Robledillo, Guillermo Martínez, Carmen Pire, Rosa María Martínez‐Espinosa   +5 more
wiley   +1 more source

Trends in the utilization, expenditure and costs of noninsulin glucose‐lowering drugs in the Medicaid population: Steady increases in glucagon‐like peptide‐1 receptor agonist and sodium–glucose transporter‐2 inhibitor use, prices and expenditure

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to analyse changes in the utilization, expenditure and average cost of noninsulin glucose‐lowering drugs (GLDs) between 2008 and 2023. Methods This was a retrospective observational study of 2008–2023 data from the National Medicaid State Drug Utilization database.
Rawan O. Almadfaa
wiley   +1 more source

Bioassay-guided isolation of Fenghuang Dancong tea constituents with α-glucosidase inhibition activities

Frontiers in Nutrition, 2022
An α-glucosidase inhibition assay showed the ethanolic extract of Fenghuang Dancong tea had potential α-glucosidase inhibitory activity. The most bioactive fraction, which was obtained via bioassay-guided isolation of the extract, was further purified to
Hua Zhou, Jin Liao, Juanying Ou, Jiayu Lin, Jiayu Lin, Jie Zheng, Yifei Li, Shiyi Ou, Fu Liu   +8 more
doaj   +1 more source

Exploring the Anti‐Diabetic Potential of Anthocyanins: From Biochemical Pathways to Human Trials

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Diabetes mellitus (DM) is a global health challenge with increasing prevalence rates, particularly in low‐ and middle‐income countries. Anthocyanins (ACs) are potential bioactive compounds found in various fruits and vegetables, attracting the attention of researchers due to their possible role in managing diabetes and its complications ...
Lakshay Panchal, Sangeeta Yadav, Akash Kumar, Tanbeer Kaur, Yashna Bawa, Sarvesh Rustagi, Rahul Mehra   +6 more
wiley   +1 more source

Insight into the Inhibitory Mechanisms of Hesperidin on α-Glucosidase through Kinetics, Fluorescence Quenching, and Molecular Docking Studies

Foods, 2023
The α-glucosidase inhibitor is of interest to researchers due to its association with type-II diabetes treatment by suppressing postprandial hyperglycemia. Hesperidin is a major flavonoid in orange fruit with diverse biological properties.
Kumaravel Kaliaperumal, Linyan Zhang, Liangliang Gao, Qin Xiong, Yan Liang, Yueming Jiang, Jun Zhang   +6 more
doaj   +1 more source

Diels-alder cycloaddition in the synthesis of 1-azafagomine, analogs, and derivatives as glycosidase inhibitors [PDF]

, 2012
This comprehensive review deals with the synthesis of 1-azafagomine, analogs, and derivatives having the Diels-Alder cycloaddition as the key step. Most of the compounds referred are racemic or have been resolved by lipase transesterification.
Alves, M. José, Fortes, A. Gil, Salgueiro, D. A. L., Sousa, Cristina   +3 more
core   +1 more source

Antidiabetic Potential of Ligands from NEIST_PMIB_06, Bacterium Associated with Hawaijar (Fermented Soy Food): Insight from in Vitro and in Silico Studies

ChemFoodChem, EarlyView.
ABSTRACT In this study, a bacterium (NEIST_PMIB_06) was isolated from Hawaijar, a fermented soy food from Manipur, Northeast India. The bacterium was inoculated and incubated to isolate bioactive compounds. Liquid‐liquid extraction was performed to obtain extracts (cell‐free and cell‐based), and their efficacy was evaluated.
A Ibeyaima, Hiranmoy Barman, Prasenjit Manna   +2 more
wiley   +1 more source

Screening and functional evaluation of the glucose-lowering active compounds of total saponins of Baibiandou (Lablab Semen Album)

Digital Chinese Medicine, 2021
Objective: To screen for α-glucosidase inhibitor active compounds in the total saponins of Baibiandou (Lablab Semen Album) based on UHPLC-Q-Exactive Orbitrap MS technology and to evaluate its hypoglycemic activity in vivo.
Jun Han, Qinfang Zheng, Liangzi Fang, Xiaolong Huang   +3 more
doaj   +1 more source

Iminosugar inhibitors of carbohydrate-active enzymes that underpin cereal grain germination and endosperm metabolism [PDF]

, 2016
Starch is a major energy store in plants. It provides most of the calories in the human diet and, as a bulk commodity, it is used across broad industry sectors.
Alison M. Smith, Andriotis, Andriotis, Aoki, Asano, Asano, Bak-Jensen, Banik, Birte Svensson, Blackwell, Boisson, Burn, Burton, Burton, Chandrasekar, Chavez Montes, Comparot-Moss, Daussant, Dinges, Fincher, Finnie, Frandsen, Gibbons, Hatzfeld, Hickes, Holdsworth, Ichinose, Kihara, Kim, Kolodziejek, Lagaert, Lee, Lee, MacGregor, Martin Rejzek, Mega, Michael D. Rugen, Moreno-Risueno, Møller, Nash, O'Brien, Rejzek, Ritchie, Robert A. Field, Ruzanski, Sissons, Slade, Smith, Smith, Sonnewald, Soussillane, Stanley, Tanaka, Vasilios M. E. Andriotis, Vriet, Wheeler, Winchester, Zeeman   +57 more
core   +2 more sources