Results 31 to 40 of about 1,369,314 (252)

FLAVONOIDS FROM RHYNCHOSIA PSEUDO-CAJAN AS SUITABLE α-GLUCOSIDASE INHIBITORS AND FREE RADICAL SCAVENGERS

International Research Journal of Pharmacy, 2014
A series of nine flavonoids , 1 - 9, isolated from Rhynchosia pseudo - cajan Cambe ss., ha s been investigated in present work for their biological potential against α - glucosidase, lipoxygenase (LOX), acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes ; and antioxidant activity against diphenylpicrylhydrazyl (DPPH) radica l ...
Muhammad Athar Abbasi, Ghulam Hussain, Aziz ur Rehman, Viqar Uddin Ahmad   +3 more
openaire   +1 more source

Genistein, a soy isoflavone, is a potent α-glucosidase inhibitor [PDF]

, 2001
Genistein is an isoflavone that is known to be contained in soybean. It was proved that genistein plays a pivotal role in homeostasis in the human body. In the course of screening for useful α-glucosidase inhibitors, we isolated and identified genistein ...
Dong-Sun Lee, Lee, Sang-Han, Sang Han Lee, Sang-Han Lee, Dong Sun Lee, Lee, Dong-Sun   +5 more
core   +1 more source

THE APPLICABILITY OF THE CRYSTAL STRUCTURE OF TERMOTOGA MARITIMA 4--GLUCANOTRANSFERASE AS THE TEMPLATE FOR SULOCHRIN AS -GLUCOSIDASE INHIBITORS

Indonesian Journal of Chemistry, 2010
Interaction of sulochrin to active site of glucosidase enzyme of Termotoga maritime has been studied by employing docking method using Molecular Operating Environment (MOE), in comparison with those are reports of established inhibitor α-glucosidase such
Rizna Triana Dewi, Yulia Anita, Enade Perdana Istyastono, Akhmad Darmawan, Muhamad Hanafi   +4 more
doaj   +1 more source

α-Glucosidase Inhibitory Activity of Fermented Okara Broth Started with the Strain Bacillus amyloliquefaciens SY07

Molecules, 2022
In this work, a new strain of Bacillus amyloliquefaciens SY07 isolated from a traditional fermented soybean food was reported to possess remarkable α-glucosidase inhibitor-producing ability. Different culture media were applied for the proliferation of B.
Yifang Gao, Wenhui Bian, Yuanyuan Fang, Peng Du, Xueting Liu, Xueru Zhao, Fengjuan Li   +6 more
doaj   +1 more source

Cafestol analogues from Coffea canephora: in vitro inhibition and molecular docking to α-glucosidase

, 2022
A new cafestol-type diterpenoid, 5β-hydroxy-2-oxocafestol named coffecanepholide C (1) along with three known diterpenoids including cafestol (2), tricalysiolide A (3) and atractyligenin (4) were identified from the Coffea canephora trunks collected at ...
Thi Anh Tuyet Nguyen (9558826), Minh Hao Hoang (10763917), Vu Nhat Ha Nguyen (13774364), Thi Nga Vo (10763920)   +3 more
core   +1 more source

Coumaroyl and feruloyl flavonoid glycosides from the male flowers of Ginkgo biloba L. and their inhibitory activity against α-glucosidase

, 2021
Four flavonoid glycosides containing coumaroyl or feruloyl groups were isolated from the male flowers of Ginkgo biloba L., and compounds 3 and 4 were identified as novel compounds.
Wei-Dong Zhu (1478668), Gao Zhou (3636376), Lan-Lan Ge (11887255), Qi-Gui Mo (11887252), You-Wei Wang (8439768)   +4 more
core   +1 more source

Phytochemical profile, antioxidant activity, and inhibition of α-amylase and α-glucosidase for banana central pseudo-stem juice [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2021
The use of natural products to inhibit α-amylase and α-glucosidase is a strategy in the treatment of diabetes. This study investigated the phytochemical profile and antioxidant activity of, and α-amylase and α-glucosidase inhibition by banana central ...
Intira Koodkaew, Khwanruedee Chaiyawan, Pimchanok Satapoomin   +2 more
doaj   +1 more source

Design, synthesis, in vitro, and in silico biological evaluations of coumarin-indole hybrids as new anti-α-glucosidase agents

BMC Chemistry, 2022
Background A series of coumarin-indole hybrids was synthesized as the new α-glucosidase inhibitors. The title hybrids were considered as α-glucosidase inhibitors because had two active pharmacophores against α-glucosidase: coumarin and indole.
Davood Rezapour Niri, Mohammad Hosein Sayahi, Somayeh Behrouz, Ali Moazzam, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Bagher Larijani, Hossein Rastegar, Maryam Mohammadi-Khanaposhtani, Mohammad Mahdavi   +9 more
doaj   +1 more source

Synthesis of activity evaluation of flavonoid derivatives as ɑ-glucosidase inhibitors

Frontiers in Chemistry, 2022
Six flavonoid derivatives were synthesized and tested for anti-α-glucosidase activities. All derivatives were confirmed using NMR and HRMS and exhibited excellent inhibitory effects on α-glucosidase.
Hua Zhu, Xin Zhong
doaj   +1 more source

Rat alpha glucosidase inhibitor and phytochemicals activities of endophytic actinobacteria from Ficus deltoidea

Pakistan Journal of Pharmaceutical Sciences, 2020
Ficus deltoidea is a medicinal plant that has high endophytic actinobacteria diversity. Endophytic actinobacteria play an important role in producing various types of bioactive compounds including α-glucosidase inhibitor.
Isra Janatiningrum, Dedy Duryadi Solihin, Anja Meryandini, Yulin Lestari, West Java, Indonesia   +5 more
doaj   +1 more source