Results 11 to 20 of about 1,369,314 (252)
Inhibitory Activity and Mechanism Investigation of Hypericin as a Novel α-Glucosidase Inhibitor [PDF]
Molecules, 2021 α-glucosidase is a major enzyme that is involved in starch digestion and type 2 diabetes mellitus. In this study, the inhibition of hypericin by α-glucosidase and its mechanism were firstly investigated using enzyme kinetics analysis, real-time ...
Qi Dong, Na Hu, Huilan Yue, Honglun Wang
doaj +3 more sources
Honokiol as an α-glucosidase inhibitor [PDF]
Frontiers in PharmacologyHonokiol, a naturally occurring compound from Magnolia obovata Thunb., has many biological activities, but its anti-α-glucosidase activity is still unclear. Therefore, we determined its inhibitory effects against α-glucosidase.
Hua Zhu, Xin Zhong
doaj +4 more sources
Isolation and Characterization of an α-Glucosidase Inhibitor from Musa spp. (Baxijiao) Flowers
Molecules, 2014 The use of α-glucosidase inhibitors is considered to be an effective strategy in the treatment of diabetes. Using a bioassay-guided fractionation technique, five Bacillus stearothermophilus α-glucosidase inhibitors were isolated from the flowers of Musa ...
Zhanwu Sheng +5 more
doaj +4 more sources
Marine Drugs, 2011 Bis(2,3-dibromo-4,5-dihydroxybenzyl) ether (BDDE), derived from the marine algae, is a potential α-glucosidase inhibitor for type 2 diabetes treatment.
Xiukun Lin +3 more
doaj +4 more sources
Personal Glucose Meter for α-Glucosidase Inhibitor Screening Based on the Hydrolysis of Maltose [PDF]
Molecules, 2021 As a key enzyme regulating postprandial blood glucose, α-Glucosidase is considered to be an effective target for the treatment of diabetes mellitus.
Feng-Qing Yang +2 more
exaly +3 more sources
The formulation of lozenge using black mulberries (Morus nigra L.) leaf extract as an α-glucosidase inhibitor [PDF]
Journal of Pharmacy and Bioallied Sciences, 2020 Background: Diabetes mellitus is a chronic metabolic disease, which possibly leads to kidney, brain, heart failure, and other organ complications, subsequently harming human health. These symptoms have been prevented using the leaf of black mulberry (BM),
Arif Budiman +3 more
doaj +2 more sources
Food Science and Human Wellness, 2017 Xylariaceae sp. QGS 01, an endophytic fungus isolated from the stem of Quercus gilva Blume showed high α-glucosidase inhibitory activity. α-Glucosidase inhibitor have the role as one of carbohydrate-hydrolyzing enzymes to postpone absorption of glucose ...
Anastasia Wheni Indrianingsih +1 more
doaj +2 more sources
α-Glucosidase Inhibitor Isolated from [PDF]
Natural Product Communications, 2018 Blechum pyramidatum (Lam.) Urb. is a species of extensive medicinal use in the American continent. In fact, antidiabetic and anticancer preparations from this plant have been patented in Mexico, even though their active constituents are not yet known. It
Lilia Cherigo, Sergio Martínez-Luis
doaj +2 more sources
Inhibitory Mechanism of Quercimeritrin as a Novel α-Glucosidase Selective Inhibitor
Foods, 2023 In this study, 12 flavonoid glycosides were selected based on virtual screening and the literature, and Quercimeritrin was selected as the best selective inhibitor of α-glucosidase through in vitro enzyme activity inhibition experiments.
Fengyu Guo +8 more
doaj +3 more sources
Inhibitory Kinetics of Cyanidin-3-O-glucoside against α-Amylase and α-Glucosidase [PDF]
Shipin Kexue, 2023 The inhibitory mechanism of α-amylase and α-glucosidase by cyanidin-3-O-glucoside was investigated by ultrafiltration, high performance liquid chromatography (HPLC), enzyme kinetics, and molecular docking.
WANG Wei, CUI Yan, ZHENG Mingzhu, CAI Dan, LIU Jingsheng, LIU Meihong, LIU Huimin
doaj +3 more sources