Results 41 to 50 of about 1,369,314 (252)

Structural Dependence of Sulfated Polysaccharide for Diabetes Management: Fucoidan From Undaria pinnatifida Inhibiting α-Glucosidase More Strongly Than α-Amylase and Amyloglucosidase

Frontiers in Pharmacology, 2020
Fucoidan refers to a group of sulfated polysaccharide that is commonly obtained from various species of brown seaweed. Fucoidan has gained increased popularity among researchers in the recent years due to its numerous biological activities, including its
Hui Si Audrey Koh, Hui Si Audrey Koh, Jun Lu, Jun Lu, Jun Lu, Jun Lu, Weibiao Zhou, Weibiao Zhou, Weibiao Zhou   +8 more
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Intestinal Production of Alpha-Glucosidase Inhibitor by Bacillus coagulans Spores

Microorganisms, 2023
This study examines the possibility of directly producing and utilizing useful substances in the intestines of animals using anaerobic bacteria that can grow in the intestines of animals.
Hee-Woong Kim, Soo-Young Choi, Deug-Chan Lee, Hae-Ik Rhee   +3 more
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α-Glucosidase and α-Amylase Inhibitory Compounds from three African Medicinal Plants: An Enzyme Inhibition Kinetics Approach

Natural Product Communications, 2017
The quest to find new lead compounds with anti-diabetic effects via the inhibition of α-glucosidase and α-amylase had led us to conduct bioassay guided isolation of three African medicinal plants which resulted in the identification of bicyclo[2.2.0 ...
Mohammed Auwal Ibrahim, James Dama Habila, Neil Anthony Koorbanally, Md. Shahidul Islam   +3 more
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Novel 4-formyl-1,3-phenylene-bisoxy-bis(methylene)-bis(1,2,3-triazole-N-phenylacetamide) derivatives as a new category of excellent α-glucosidase inhibitors† [PDF]

RSC Advances
A series of thirteen new 4-formyl-1,3-phenylene-bisoxy-bis(methylene)-bis(1,2,3-triazole-N-phenylacetamide) derivatives 8a–m were synthesized as potent α-glucosidase inhibitors.
Shohreh Bakhshi Varzaneh, Mohammad Hosein Sayahi, Mohammad Halimi, Seyedeh Niloufar Ghafouri, Navid Dastyafteh, Somayeh Mojtabavi, Bagher Larijani, Maryam Mohammadi-Khanaposhtani, Mohammad Mahdavi   +8 more
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Effects of Acarbose, an α-Glucosidase Inhibitor (BAY G 5421), on Orally Loaded Glucose, Maltose and Sucrose and on Blood Glucose Control in Non-Insulin-Dependent Diabetics [PDF]

, 1985
1985-01Fifty g glucose, 50g maltose and 50g sucrose were loaded to 12 nonobese healthy male volunteers with and without 100 or 300 mg α-glucosidase inhibitor, acarbose, and the inhibitory effect on digestion and absorption of these saccharides was ...
NODA, AIJI, OKUMURA, NOBUYOSHI, KONDO, TAKAHARU, HAYAKAWA, TETUO   +3 more
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Carnitine is a pharmacological allosteric chaperone of the human lysosomal α-glucosidase

, 2022
Pompe disease is an inherited metabolic disorder due to the deficiency of the lysosomal acid α-glucosidase (GAA). The only approved treatment is enzyme replacement therapy with the recombinant enzyme (rhGAA).
Roberta Iacono (4610482), Gianfranco Peluso (284822), Antonietta Tarallo (5944370), Caterina Porto (4610479), Marco Moracci (21885), Maria Carmina Ferrara (11943696), Gerlind Sulzenbacher (11943708), Beatrice Cobucci-Ponzano (21879), Giancarlo Parenti (754610), Sandra Strollo (11943702), Carla Damiano (11943699), Véronique Roig-Zamboni (11943705), Nadia Minopoli (11943693)   +12 more
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Isolation of a Novel Anti-Diabetic α-Glucosidase Oligo-Peptide Inhibitor from Fermented Rice Bran

, 2023
At present, the incidence rate of diabetes is increasing gradually, and inhibiting α-glucosidase is one of the effective methods used to control blood sugar.
Jingfei Hu, Jing Lu, Mingsheng Lyu, Shujun Wang, Xiaohua Lai, Huanyu Wang, Xudong Wu, Nanhai Weng   +7 more
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Successfully Treated Pneumatosis Cystoides Intestinalis with Pneumoperitoneum Onset in a Patient Administered α-glucosidase Inhibitor [PDF]

, 2013
An 80-year-old woman, who had been administered α-glucosidase inhibitor for diabetes, was brought to the hospital with the sensation of abdominal fullness and pain.
Tanabe, Shunsuke, Shirakawa, Yasuhiro, Maeda, Naoaki, Sakurama, Kazufumi, Ohara, Toshiaki, Noma, Kazuhiro, Fujiwara, Toshiyoshi, Takehara, Yuko, Katsube, Ryoichi   +8 more
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Comparison of Efficacies of a Dipeptidyl Peptidase IV Inhibitor and α-Glucosidase Inhibitors in Oral Carbohydrate and Meal Tolerance Tests and the Effects of Their Combination in Mice

Journal of Pharmacological Sciences, 2007
E3024 (3-but-2-ynyl-5-methyl-2-piperazin-1-yl-3,5-dihydro-4H-imidazo[4,5-d]pyridazin-4-one tosylate) is a dipeptidyl peptidase IV (DPP-IV) inhibitor. Since the target of both DPP-IV inhibitors and α-glucosidase inhibitors is the lowering of postprandial ...
Kazuto Yamazaki, Takashi Inoue, Nobuyuki Yasuda, Yoshiaki Sato, Tadashi Nagakura, Osamu Takenaka, Richard Clark, Takao Saeki, Isao Tanaka   +8 more
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Intestinal α-Glucosidase Inhibitors in Achillea millefolium [PDF]

, 2017
Achillea millefolium is a plant used as a component of anti-diabetic preparation but the bioactive compounds responsible for its use are not known. Inhibition of intestinal α-glucosidase is a preferable effect for prevention and treatment of diabetes ...
Kato, Eisuke, Noda, Kota, Kawabata, Jun
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