BMC Plant Biology, 2019 CRISPR/Cas9 gene editing is now revolutionizing the ability to effectively modify plant genomes in the absence of efficient homologous recombination mechanisms that exist in other organisms.
P. Do +7 more
semanticscholar +1 more source
Metabolomics driven analysis by UAEGC-MS and antioxidant activity of Chia (Salvia hispanica L.) commercial and mutant seeds [PDF]
, 2018 Chia is a food plant producing seeds which have seen increasing interest owing to their health benefits. This work is the first report on the metabolite profile, total polyphenols and antioxidant activity of chia seeds, determined by ultrasound-assisted ...
Amato, Mariana +4 more
core +2 more sources
Advances in Bioprinting to Model Immune‐Mediated Skin Diseases
Advanced Healthcare Materials, EarlyView.This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández +4 more
wiley +1 more source
PhytoMilk: Effects of botanical composition and harvest system of legume/grass silage on fatty acid, α-tocopherol and β-carotene concentration in organic forage and milk [PDF]
, 2010 Red clover and high proportion of forage in dairy cow diet increases the concentration of bioactive substances in milk, e.g. unsaturated fatty acids and antioxidants. In the present experiment twenty-four Swedish Red dairy cows were fed three silages in
Gustavsson, Anne-Maj +3 more
core
Acute Hypercapnia/Ischemia Alters the Esterification of Arachidonic Acid and Docosahexaenoic Acid Epoxide Metabolites in Rat Brain Neutral Lipids. [PDF]
, 2020 In the brain, approximately 90% of oxylipins are esterified to lipids. However, the significance of this esterification process is not known. In the present study, we (1) validated an aminopropyl solid phase extraction (SPE) method for separating ...
Bazinet, Richard P +7 more
core +1 more source
Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development
Advanced Science, EarlyView.This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen +11 more
wiley +1 more source
Proceedings of the Nutrition Society, 2019 SFA intakes have decreased in recent years, both in Ireland and across other European countries; however a large proportion of the population are still not meeting the SFA recommendation of
Y. Lenighan, B. McNulty, H. Roche
semanticscholar +1 more source
The biosynthesis of galactolipids in red clover (Trifolium pratense) : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry [PDF]
, 1972 Galactolipids occur in all cells capable of the photosynthetic evolution of oxygen. The main galactolipids are monogalactosyl diglyceride (MGDG), digalactosyldiglyceride (DGDG) and sulfolipid (SL), MGDG being the most abundant.
Bycroft, Wesley
core
Lipid peroxidation is essential for α-synuclein-induced cell death. [PDF]
, 2015 Parkinson's disease is the second most common neurodegenerative disease and its pathogenesis is closely associated with oxidative stress. Deposition of aggregated α-synuclein (α-Syn) occurs in familial and sporadic forms of Parkinson's disease.
Abramov, AY +5 more
core +2 more sources
Advanced Science, EarlyView.This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang +9 more
wiley +1 more source