Results 81 to 90 of about 737,596 (164)

Arzanol: A Review of Chemical Properties and Biological Activities

Plants
Arzanol, a prenylated phloroglucinol–α-pyrone heterodimer, displays a broad range of pharmacological properties. This review compiles findings from 2007 to 2025 on its chemistry, conformational behavior, bioactivities, molecular targets, and ...
Yulian Voynikov
doaj   +1 more source

Arzanol, a Potent mPGES-1 Inhibitor: Novel Anti-Inflammatory Agent

The Scientific World Journal, 2013
Arzanol is a novel phloroglucinol α-pyrone, isolated from a Mediterranean plant Helichrysum italicum (Roth) Don ssp. microphyllum which belongs to the family Asteraceae.
Pankaj S. Kothavade, Dnyaneshwar M. Nagmoti, Vipin D. Bulani, Archana R. Juvekar   +3 more
doaj   +1 more source

A new 3,6-dialkyl-α-pyrone produced by the heterologous expression of a PKS-NRPS hybrid enzyme derived from a Pestalotiopsis endophyte

Genome mining of polyketide synthase (PKS)-nonribosomal peptide synthetase (NRPS) hybrid enzymes independent of trans-acting enoyl reductase using our in-house fungal draft genomic library led to the discovery of a unique PKS-NRPS hybrid enzyme, PbpsA ...
Shi, Yue, Tan, Yu Pei, Shivas, Roger G., Asai, Teigo, Davis, Rohan A, Shivas, Roger G, Sugawara, Akihiro, Davis, Rohan A., Ozaki, Taro, Morishita, Yohei   +9 more
core   +1 more source

Structure determination of a 4-pyrone from the liverwort Plagiochila bifaria (Sw.) Lindenb. (Plagiochilaceae) [PDF]

, 2008
The centenary of the presentation in 1907 of the "polyketide" hypothesis by Collie, along with his use of a 4-pyrone as an example, is marked by reporting the discovery and isolation of 2-(3,4-dimethoxyphenethyl)-6-methyl-4-pyrone from <i> ...
Rycroft, D.S.
core  

α‑Pyrone Derivatives from Calcarisporium arbuscula Discovered by Genome Mining

, 2023
A highly reducing polyketide synthase (HRPKS) gene cluster from the genome of Calcarisporium arbuscula was identified through genome mining. Heterologous expression of this cluster led to the production of four new α-pyrone compounds, calcapyrones A (1 ...
Jia-Yu Dong (17336879), Man-Cheng Tang (1493491), Ling Liu (143030)   +2 more
core   +1 more source

Violapyrones H and I, New Cytotoxic Compounds Isolated from Streptomyces sp. Associated with the Marine Starfish Acanthaster planci

Marine Drugs, 2014
Two new α-pyrone derivatives, violapyrones H (1) and I (2), along with known violapyrones B (3) and C (4) were isolated from the fermentation broth of a marine actinomycete Streptomyces sp.
Hee Jae Shin, Hwa-Sun Lee, Jong Seok Lee, Junho Shin, Min Ah Lee, Hyi-Seung Lee, Yeon-Ju Lee, Jieun Yun, Jong Soon Kang   +8 more
doaj   +1 more source

Albidopyrone, a new α-pyrone-containing metabolite from marine-derived Streptomyces sp. NTK 227

, 2009
Albidopyrone, a new α-pyrone-containing secondary metabolite, was produced by Streptomyces sp. NTK 227, a strain isolated from Atlantic Ocean sediment and found to be a member of the Streptomyces albidoflavus 16S rRNA gene clade.
Goodfellow, Michael, Claudia Hohmann, Krämer, Marco, Roselyn Brown, Roderich D Süssmuth, Graeme Nicholson, Nicholson, Graeme, Fiedler, Hans-Peter, Imhoff, Johannes, Hohmann, Claudia, Marco Krämer, Brown, Roselyn, Süssmuth, Roderich D, Schneider, Kathrin, Bruntner, Christina, Süssmuth, Roderich, Imhoff, Johannes F., Johannes F Imhoff, Amanda L Jones, Hans-Peter Fiedler, Michael Goodfellow, Christina Bruntner, Jones, Amanda, Jones, Amanda L, Kathrin Schneider   +24 more
core   +1 more source

Reactivity of a platinum η1-formylketenyl complex synthesis of a platinum α-pyrone derivative via generation and trapping of a C3H2O2 species. 20

, 1993
The formylketenyl platinum complex, trans-bis(tricyclohexylphosphine)(η1-formylketenyl)(hydride)platinum(II), trans-(PCy3)2(H)Pt[η1-C(CHO)CO] (1), reacts with acids causing the cleavage of the Pt-C bond and generating the species C3H2O2 which is trapped ...
PANDOLFO, LUCIANO, PAIARO G, VALLE G, TRALDI P., GANIS P   +4 more
core   +1 more source

Secondary Metabolites Produced by an Endophytic Fungus Pestalotiopsis sydowiana and Their 20S Proteasome Inhibitory Activities

Molecules, 2016
Fungal endophytes have attracted attention due to their functional diversity. Secondary metabolites produced by Pestalotiopsis sydowiana from a halophyte, Phragmites communis Trinus, were investigated.
Xuekui Xia, Soonok Kim, Changheng Liu, Sang Hee Shim   +3 more
doaj   +1 more source

Analysis of TETRAKETIDE α-PYRONE REDUCTASE Function in Arabidopsis thaliana Reveals a Previously Unknown, but Conserved, Biochemical Pathway in Sporopollenin Monomer Biosynthesis  

, 2010
The precise structure of the sporopollenin polymer that is the major constituent of exine, the outer pollen wall, remains poorly understood. Recently, characterization of Arabidopsis thaliana genes and corresponding enzymes involved in exine formation ...
Etienne Grienenberger, Benjamin Lallemand, Dimitri Heintz, Thierry Heitz, Sung Soo Kim, Clarice de Azevedo Souza, Carl J. Douglas, Michel Legrand, Pierrette Geoffroy   +8 more
core   +1 more source