Results 61 to 70 of about 737,596 (164)
Effect of Culture Conditions on Metabolite Production of Xylaria sp.
Molecules, 2015 Seeking a strategy for triggering the cryptic natural product biosynthesis to yield novel compounds in the plant-associated fungus Xylaria sp., the effect of culture conditions on metabolite production was investigated.
Hongqi Zhang +7 more
doaj +1 more source
Comprehensive Review on Medicinal Applications of Coumarin-Derived Imine–Metal Complexes
Molecules, 2022 Coumarins are fused six-membered oxygen-containing benzoheterocycles that join two synthetically useful rings: α-pyrone and benzene. A survey of the literature shows that coumarins and their metal complexes have received great interest from synthetic ...
Siddappa A. Patil +6 more
doaj +1 more source
Advanced Science, Volume 13, Issue 27, 13 May 2026.This study presents the first telomere‐to‐telomere genomes and population resources for Diaporthe pathogens, uncovering the largest known fungal repertoire of secondary metabolite gene clusters. Structural variations and horizontal gene transfer drive cluster diversification, while specific rapidly evolving clusters control virulence, offering novel ...
Kainan Li +9 more
wiley +1 more source
Marine Drugs, 2010 The new secondary metabolites verrucosidinol (1) and its derivative verrucosidinol acetate (2), together with a potent neurotoxin verrucosidin (3), a congener norverrucosidin (4) and a mixture of two known phytotoxic metabolites terrestric acids (5 and 6)
Huanqin Dai +7 more
doaj +1 more source
Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.ABSTRACT Liberoid coffee (Coffea liberica group), comprising varieties of Liberica and Excelsa coffee types, is gaining attention for its unique chemical composition and sensory potential. However, its quality remains under‐optimized due to limited understanding of genotype‐specific traits and processing responses.
Noor Ariefandie Febrianto, Fan Zhu
wiley +1 more source
Breaking Down Barriers: CorA Effectively Targets Staphylococcal Biofilms in Vitro and in Vivo
ChemMedChem, Volume 21, Issue 7, 14 April 2026.Corallopyronin A (CorA), a natural alpha‐pyrone antibiotic, penetrates Staphylococcus aureus biofilms and inhibits RNA polymerase. This work demonstrates CorA's superior efficacy compared to rifampicin and dalbavancin in reducing viable loads in biofilms both in vitro and in vivo. Graphic created in https://BioRender.com.
Stefania De Benedetti +21 more
wiley +1 more source
AntibioticsAn investigation of ×19 soil samples collected under the auspices of the Australian citizen science initiative, Soils for Science, returned ×559 chemically dereplicated microbial isolates, of which ×54 exhibited noteworthy anthelmintic activity against ...
Shengbin Jin +7 more
doaj +1 more source
MedComm, Volume 7, Issue 4, April 2026.This graphical abstract shows the antibacterial potential of phytochemicals from 15 spices, showcasing key compounds, their extraction methods, and mechanisms of action. It highlights membrane disruption, ROS generation, enzyme inhibition, and biofilm prevention as core antibacterial pathways.
Hettiyahandi Binodh De Silva +3 more
wiley +1 more source
Food Frontiers, Volume 7, Issue 2, March 2026.ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani +3 more
wiley +1 more source
Nodulisporipyrones A–D, new bioactive α-pyrone derivatives from Nodulisporium sp.
, 2015 Four new α-pyrone derivatives, nodulisporipyrones A–D (1–4), were isolated from the extract of an endolichenic fungal strain Nodulisporium sp. (65-12-7-1) that was fermented with rice.
Liang-Dong Guo (463621) +9 more
core +1 more source