Results 41 to 50 of about 737,596 (164)

New 2-pyrone-based hydrazones: Synthesis, spectral characterisation, UV–visible study and evaluation of the antiradicalar activity

, 2016
The synthesis of new 2-pyrone-based hydrazones has been prepared by the coupling of 6-methyl-2H-furo[3,2-c]pyran-3,4-dione with diazonium salts, obtained by diazotization of aniline derivatives.
Malika Makhloufi-Chebli (3607037), Anissa Amar (1425829), Djamila Oukacha-Hikem (3607046), Artur M. S. Silva (1577557), Houria Bouherrou (3607043), Yahia Rachedi (3607034), Maamar Hamdi (3607040), Hacène Meghezzi (3607031)   +7 more
core   +1 more source

Contrasting ring-opening propensities in UV-excited α-pyrone and coumarin [PDF]

, 2016
The photoisomerisation dynamics following excitation to the S1 electronic state of two structurally related heterocyclic molecules, α-pyrone and coumarin, in acetonitrile solution have been probed by time-resolved vibrational absorption spectroscopy ...
Murdock, Daniel, Clark, Ian P., Sazanovich, Igor V, Orr-Ewing, Andrew J, Taketsugu, Tetsuya, Harabuchi, Yu, Ingle, Rebecca A, Maeda, Satoshi, Ashfold, Michael N R   +8 more
core   +1 more source

An Efficient Chemoenzymatic Approach towards the Synthesis of Rugulactone

Molecules, 2018
Rugulactone is a natural product isolated from the plant Cryptocarya rugulosa. It has shown very important biological activity as an inhibitor of the nuclear factor κB (NF-κB) activation pathway.
Theodore Tyrikos-Ergas, Vasileios Giannopoulos, Ioulia Smonou   +2 more
doaj   +1 more source

New Insights into Chemical and Biological Properties of Funicone-like Compounds

Toxins, 2022
Funicone-like compounds are a homogeneous group of polyketides that, so far, have only been reported as fungal secondary metabolites. In particular, species in the genus Talaromyces seem to be the most typical producers of this group of secondary ...
Maria Michela Salvatore, Marina DellaGreca, Anna Andolfi, Rosario Nicoletti   +3 more
doaj   +1 more source

Mesityl‐Substituted Azuleno[1′,2′:4,5]pyrrolo[2,3‐b]quinoxalines: Synthesis, Functionalization, Photophysical, and Electrochemical Properties

European Journal of Organic Chemistry, EarlyView.
Azuleno[1′,2′:4,5]pyrrolo[2,3‐b]quinoxaline with a mesityl group as a solubilizing group was synthesized. By synthesizing derivatives in which various functional groups were introduced into two electronically distinct sites, the pyrrole nitrogen atom and the azulene five‐membered ring, we were able to reveal that the photophysical and electrochemical ...
Ryuta Sekiguchi, Hiroki Mizuno, Ikumi Uchiyama, Souta Yuruka, Atsuya Shimizu, Taku Shoji, Shunji Ito   +6 more
wiley   +1 more source

Formal synthesis of natural 1, 3-polyol/α-pyrone diastereoisomers

, 2008
A stereoselective formal synthesis of diastereoisomers of 1,3-polyol/α-pyrone antifungal natural products isolated from Ravensara anisata has been achieved involving epoxide opening and asymmetric allylation as key ...
Gopal, Peddabuddi, Sabitha, Gowravaram, Yadav, Jhillu S.   +2 more
core   +1 more source

Caffeylpyruvate hydrolase from the bioluminescent fungus Neonothopanus gardneri is the key recycling enzyme in the fungal bioluminescence pathway

The FEBS Journal, EarlyView.
Caffeic acid is a central metabolite in the fungal bioluminescence pathway. We identified and characterized caffeylpyruvate hydrolase from Neonothopanus gardneri (ngarCPH) and demonstrate its ability to hydrolyze fungal oxyluciferin into caffeic and pyruvic acids, confirming a complete and self‐sustained fungal bioluminescence cycle.
Caio K. Zamuner, Douglas M. M. Soares, Bianca B. Nóbrega, Etelvino J. H. Bechara, Zinaida M. Kaskova, Alexander S. Mishin, Karen S. Sarkisyan, Ilia V. Yampolsky, Cassius V. Stevani   +8 more
wiley   +1 more source

Dietary Polyphenols as Natural Modulators of NF‐κB Signaling in Inflammation‐Driven Non‐Communicable Diseases: Focus on Cancer

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Dietary polyphenols and phytochemicals suppress NF‐κB signaling. Mechanistically, by inhibiting IκBα degradation and preventing nuclear translocation of p65/p50 complexes, the polyphenols reduce the expression of pro‐inflammatory and pro‐survival genes, thereby decreasing overall cancer cell survival.
Khuzin Dinislam, Anas Shamsi, Syed Tasqeruddin, Moyad Shahwan   +3 more
wiley   +1 more source

A concise route to α'-methoxy-γ-pyrones and verticipyrone based upon the desymmetrization of α,α'-dimethoxy-γ-pyrone.

, 2010
International audienceTwo steps is the rule : A concise synthesis of versatile α′‐methoxy‐γ‐pyrones (see scheme) is described that uses an innovative desymmetrization of α,α′‐dimethoxy‐γ‐pyrone, relying upon conjugate addition of nucleophiles.
Rosso, Helèna, d'Herouville, Florent, Jacques Maddaluno, Prandi, Cristina, Matthias Henrot, Michaël De Paolis, Cristina Prandi, Florent d'Herouville, de Paolis, Michaël, Maddaluno, Jacques, Henrot, Matthias, Helèna Rosso   +11 more
core   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, Volume 40, Issue 7, Page 4676-4709, July 2026.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source