Results 51 to 60 of about 5,199 (166)

Telomere‐to‐Telomere Genomes Reveal that Multiscale Evolution Shapes the Largest Metabolic Arsenal of Diaporthe Fungi

open access: yesAdvanced Science, Volume 13, Issue 27, 13 May 2026.
This study presents the first telomere‐to‐telomere genomes and population resources for Diaporthe pathogens, uncovering the largest known fungal repertoire of secondary metabolite gene clusters. Structural variations and horizontal gene transfer drive cluster diversification, while specific rapidly evolving clusters control virulence, offering novel ...
Kainan Li   +9 more
wiley   +1 more source

Bacuri and macaxeira waste: physical-chemical characterization and production of coconut bioaroma by solid-state fermentation

open access: yesRevista Brasileira de Ciências Ambientais
Agro-industrial waste is considered a global concern. Many of these residues are composed of considerable amounts of lipids and starch that can potentially be applied in bioprocesses, as is the case with residues from the bacuri fruit (Platonia insignis ...
Adriana Silva do Nascimento   +8 more
doaj   +1 more source

Unlocking the Quality Potential of Liberoid Coffee: Advances in Composition, Processing, and Microbial Fermentation

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT Liberoid coffee (Coffea liberica group), comprising varieties of Liberica and Excelsa coffee types, is gaining attention for its unique chemical composition and sensory potential. However, its quality remains under‐optimized due to limited understanding of genotype‐specific traits and processing responses.
Noor Ariefandie Febrianto, Fan Zhu
wiley   +1 more source

Emission solvatochromic, solid-state and aggregation-induced emissive α-pyrones and emission-tuneable 1H-pyridines by Michael addition–cyclocondensation sequences

open access: yesBeilstein Journal of Organic Chemistry, 2019
Starting from substituted alkynones, α-pyrones and/or 1H-pyridines were generated in a Michael addition–cyclocondensation with ethyl cyanoacetate. The peculiar product formation depends on the reaction conditions as well as on the electronic substitution
Natascha Breuer   +3 more
doaj   +1 more source

Higginsianins A and B, two fungal diterpenoid α-pyrones with cytotoxic activity against human cancer cells [PDF]

open access: yes, 2019
Two new diterpenoid α-pyrones, named higginsianins A and B, were isolated from the mycelium of the microbial fungus Colletotrichum higginsianum grown in liquid culture.
Calabrò, Viola   +7 more
core   +1 more source

Breaking Down Barriers: CorA Effectively Targets Staphylococcal Biofilms in Vitro and in Vivo

open access: yesChemMedChem, Volume 21, Issue 7, 14 April 2026.
Corallopyronin A (CorA), a natural alpha‐pyrone antibiotic, penetrates Staphylococcus aureus biofilms and inhibits RNA polymerase. This work demonstrates CorA's superior efficacy compared to rifampicin and dalbavancin in reducing viable loads in biofilms both in vitro and in vivo. Graphic created in https://BioRender.com.
Stefania De Benedetti   +21 more
wiley   +1 more source

Multiple roles and effects of a novel Trichoderma hydrophobin [PDF]

open access: yes, 2015
Fungi belonging to the genus Trichoderma are among the most active and ecologically successful microbes found in natural environments, as they are able to use a variety of substrates and affect the growth of other microbes and virtually any plant species.
David Turrà   +12 more
core   +1 more source

Antimicrobial Effect of Spices and Their Phytochemicals: A Novel Approach to Overcoming Antibiotic Resistance

open access: yesMedComm, Volume 7, Issue 4, April 2026.
This graphical abstract shows the antibacterial potential of phytochemicals from 15 spices, showcasing key compounds, their extraction methods, and mechanisms of action. It highlights membrane disruption, ROS generation, enzyme inhibition, and biofilm prevention as core antibacterial pathways.
Hettiyahandi Binodh De Silva   +3 more
wiley   +1 more source

Synthetic and Structure-Activity Relationship of Insecticidal Bufadienolides

open access: yesNatural Product Communications, 2014
A new synthetic analog of bufadienolide, methyl isobryophyllinate A ( 1 ), and a known synthetic analog, methyl isobersaldegenate-1,3,5-orthoacetate ( 2 ), were obtained by methanolysis of bryophyllin A ( 3 ) and bersaldegenin-1,3,5-orthoacetate ( 5 ) in
Ace Tatang Hidayat   +5 more
doaj   +1 more source

Biosynthesis of oxygen and nitrogen-containing heterocycles in polyketides [PDF]

open access: yes, 2016
This review highlights the biosynthesis of heterocycles in polyketide natural products with a focus on oxygen and nitrogen-containing heterocycles with ring sizes between 3 and 6 atoms.
Hahn, Frank, Hemmerling, Franziska
core   +3 more sources

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