Results 61 to 70 of about 2,390 (158)

T‐Shaped 8‐Aryl(ethynyl)‐Substituted Psoralens With Tunable Charge‐Transfer Absorption

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 8, 25 February 2026.
Starting from 8‐methoxypsoralen, new 8‐arylated and 8‐alkynylated psoralen derivatives are accessible by cross‐coupling. These T‐shaped π‐expanded chromophores are luminescent and photophysics reveal a highly polar excited state with tunable charge‐transfer character.
Lena T. Leusch, Thomas J. J. Müller
wiley   +1 more source

Novel Antifungal Scaffold Targeting Tubulin Overcomes Sclerotinia Sclerotiorum Resistance

open access: yesAdvanced Science, Volume 13, Issue 8, 9 February 2026.
Addressing pesticide resistance, novel chromone‐acylhydrazone hybrids targeting fungal tubulin are synthesized. Compound G24 potently inhibited S. sclerotiorum (EC50 = 0.21µg mL−1) and demonstrated enhanced field performance via microencapsulation, offering a sustainable strategy against resistance and for global food security.
Lihui Shao   +5 more
wiley   +1 more source

Mycobacterial F420H2-Dependent Reductases Promiscuously Reduce Diverse Compounds through a Common Mechanism

open access: yesFrontiers in Microbiology, 2017
An unusual aspect of actinobacterial metabolism is the use of the redox cofactor F420. Studies have shown that actinobacterial F420H2-dependent reductases promiscuously hydrogenate diverse organic compounds in biodegradative and biosynthetic processes ...
Chris Greening   +18 more
doaj   +1 more source

Enhanced uptake, high selective and microtubule disrupting activity of carbohydrate fused pyrano-pyranones derived from natural coumarins attributes to its anti-malarial potential

open access: yesMalaria Journal, 2019
Background Malaria is one of the deadliest infectious diseases caused by protozoan parasite of Plasmodium spp. Increasing resistance to anti-malarials has become global threat in control of the disease and demands for novel anti-malarial interventions ...
Sonal Gupta   +7 more
doaj   +1 more source

Humic acid from Shilajit – a physico-chemical and spectroscopic characterization [PDF]

open access: yesJournal of the Serbian Chemical Society, 2010
Shilajit is a blackish–brown exudation, consisting of organic substances, metal ions and minerals, from different formations, commonly found in the Himalayan region (1000–3000 m) from Nepal to Kashmir.
SURAJ P. AGARWAL   +4 more
doaj  

Ternifolipyrons A-J: new cytotoxic α-pyrones from Isodon ternifolius (D. Don) Kudô. [PDF]

open access: yesRSC Adv, 2023
Elshamy AI   +8 more
europepmc   +1 more source

The effects of Shilajit supplementation on fatigue-induced decreases in muscular strength and serum hydroxyproline levels

open access: yesJournal of the International Society of Sports Nutrition, 2019
Background Shilajit is a safe, fluvic mineral complex exudate that is common to Ayurvedic medicine and is composed of fulvic acids, dibenzo-α-pyrones, proteins, and minerals.
Joshua L. Keller   +5 more
doaj   +1 more source

Insights into Molecular Mechanisms of Polyphenolic Compounds from Helichrysum italicum by Inverse Molecular Docking Fingerprint Approach

open access: yesPharmaceuticals
Background/Objectives: Natural compounds occupy a pharmacologically rich chemical space, characterized by abundant scaffolds, extensive functional group elaboration, and defined stereochemistry.
Veronika Furlan   +3 more
doaj   +1 more source

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