Results 221 to 230 of about 91,213 (314)

Constipation Is Linked to Neuroinflammation in Early Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Constipation is a risk factor for the onset and accelerated progression of Parkinson's disease (PD), but the mechanisms underlying this association are unknown. Neuroinflammation in PD has been demonstrated in postmortem and neuroimaging studies; however, its relationship with constipation has not been investigated.
Marta Camacho, Julia C. Greenland, Alexander R.D. Peattie, Lennart R.B. Spindler, Jonathan Holbrook, Lakmini Kahanawita, Tim D. Fryer, Young T. Hong, Caroline H. Williams‐Gray   +8 more
wiley   +1 more source

Heat shock protein 10 as a chaperone modulating α-synuclein amyloid fibril formation. [PDF]

Protein Sci
Larsson JNK, Kumar R, Buratti FA, Nyström S, Wittung-Stafshede P, Hammarström P.   +5 more
europepmc   +1 more source

Silymarin-BasedNanosheets Efficiently Protect Mitochondriaagainst Oxidative Damage Mediated by α‑Synuclein AmyloidAggregates

Zahra Mahmoudi Eshkaftaki (22600734), Saeed Emadi (22600737), Ali Akbar Meratan (4588651)   +2 more
openalex   +1 more source

shRNA targeting α-synuclein prevents neurodegeneration in a Parkinson’s disease model [PDF]

, 2015
Alevtina Zharikov, Jason R. Cannon, Vı́ctor Tapias, Qing Bai, Max Horowitz, Vipul Shah, Amina El Ayadi, Teresa G. Hastings, J. Timothy Greenamyre, Edward A. Burton   +9 more
openalex   +1 more source

Cerebrospinal Fluid Biomarkers of NLRP3 Pathway, Immune Dysregulation, and Neurodegeneration in Parkinson's Disease: A Meta‐Analysis

Movement Disorders, EarlyView.
Abstract Background The activation of the NOD‐, LRR‐ and pyrin domain‐containing protein 3 (NLRP3) inflammasome and associated immune dysregulation is one of the key pathological processes preceding and accompanying α‐synuclein pathology, neuronal damage, and cell death in Parkinson's disease (PD).
Alina‐Măriuca Marinescu, Venissa Machado, Gennaro Pagano, Nicoletta Milani Muelhardt, Thomas Kustermann, Eva Zsuzsanna Mracsko, Kathrin Brockmann, Nima Shariati, Judith Anzures‐Cabrera, Bastian Zinnhardt   +9 more
wiley   +1 more source

Aggregation and Propagation of α-Synuclein in Parkinson's Disease: A Bibliometric Perspective. [PDF]

Brain Behav
Zhang X, Ma Y, Gao G, Wu Q.
europepmc   +1 more source

Neurodegeneration and the ordered assembly of α-synuclein [PDF]

, 2017
Maria Grazia Spillantini, Michel Goedert
openalex   +1 more source

Parkinson's‐Linked LRRK2 and GBA1 Mutations Modulate the Peripheral Immune Response to Pseudomonas aeruginosa

Movement Disorders, EarlyView.
Abstract Background Peripheral disease mechanisms such as immune dysregulation may contribute to Parkinson's disease (PD). To investigate interactions between common PD mutations and immune responses to environmental pathogens, we studied responses to Pseudomonas aeruginosa (P.
Julian R. Mark, Hannah A. Staley, Ann M. Titus, Julian Agin‐Liebes, Alicia Garrido, Laura Hughes, Nicolas Dzamko, Rebecca L. Wallings, Malú Gámez Tansey   +8 more
wiley   +1 more source

Quantitative Analysis of α-Synuclein Solubility in Living Cells Using Split GFP Complementation

, 2012
Ahmed Kothawala, Kiri Kilpatrick, Jose Andres Novoa, Laura Segatori   +3 more
openalex   +2 more sources

Beyond Pathology: α‐Synuclein Homeostasis and Three Principles to Guide Research

Movement Disorders Clinical Practice, EarlyView.
Alberto J. Espay, Andrew J. Lees
wiley   +1 more source