Results 261 to 270 of about 83,002 (289)

Copper Dyshomeostasis Affects α-Synuclein Clearance Mechanisms in Parkinson's Disease: Insights from In Vitro Models and Translational Evidence. [PDF]

Int J Mol Sci
Musarò D, Greco M, Lanza M, Damato M, Maffia M.   +4 more
europepmc   +1 more source

Neuroprotective roles of klotho: Molecular pathways and therapeutic implications for cognitive health in neurological and psychiatric diseases

Experimental Physiology, EarlyView.
Abstract Klotho, a pleiotropic protein initially identified for its role in kidney function, has garnered significant attention for its neuroprotective properties in various neurodegenerative diseases. It regulates key processes, such as oxidative stress, neuroinflammation, synaptic plasticity and myelination, all crucial for maintaining neuronal ...
Amir Arsalan Ghahari, Leylinaz Safaeihavadaragh, Mehrdad Nourizadeh, Shaghayegh Davari, Saba Safaei, Farshad Zare, Safa Alkayyat, Erfan Kamali Far   +7 more
wiley   +1 more source

Drug screening for α-synuclein aggregation inhibitors via multimodal graph neural network. [PDF]

Brief Bioinform
Gu T, Ran Z, Li W, Guo X, Li B, Li F, Jia C.   +6 more
europepmc   +1 more source

Molecular mechanisms underlying Parkinson's disease and role of phytochemicals, α-synuclein, sirtuins, and incretin mimetics in potential therapy. [PDF]

Front Pharmacol
Juthi SS, Ansari P, Ahmed MF, Khan JT, Seidel V, Kumar S, Kumari R, McKillop A, Abdel-Wahab YHA, Flatt PR.   +9 more
europepmc   +1 more source

In-Cell Residue-Resolved NMR of Micromolar α-Synuclein and Tau at 310 K. [PDF]

J Am Chem Soc
Chérot H, Pred'homme T, Thai R, Théodoro F, Castelli F, Theillet FX.   +5 more
europepmc   +1 more source

Lipid membrane remodeling by myristic acid treatment reverses Parkinson's disease α-synuclein phenotypes in patient neurons. [PDF]

NPJ Metab Health Dis
Pacheco JA, Sauli G, Fonseca-Ornelas L, Cirka H, Kumari D, Hazo M, Jeanfavre S, Vendramini PH, Muratore CR, Clish CB, Selkoe D, Fanning S.   +11 more
europepmc   +1 more source

Clinical Validation of α-Synuclein in Salivary Extracellular Vesicles as a Biomarker for Parkinson's Disease: A Longitudinal Study. [PDF]

Eur J Neurol
Gurgone A, Cardinale V, Tangari MM, Budicin S, Comai D, Ledda C, Lopiano L, Camussi G, Zibetti M, Giustetto M.   +9 more
europepmc   +1 more source

Erratum: Smith et al., "α-Synuclein Phosphorylation Enhances Eosinophilic Cytoplasmic Inclusion Formation in SH-SY5Y Cells". [PDF]

J Neurosci
europepmc   +1 more source

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Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes

Cell, 2021
Hannah Scheiblich, Dilek Mercan, Susanne V Schmidt   +2 more
exaly