Anais da Academia Brasileira de CiênciasThalassemia, an autosomal recessive genetic disorder affecting production of normal globin chains, presents varying prevalence worldwide. The frequency of global α-thalassemia remains understudied, especially in Brazil, due to its genetic diversity and ...
ELIANA A. SANTOS +4 more
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Transient depletion of innate immunity in varicella infections in otherwise healthy children [PDF]
, 2009 Objective: Varicella is a common childhood infection and has a number of complications in the unvaccinated population. Perforin, found in natural killer cells, is important for the killing of virally infected cells. For this reason, the aim of this study
Ateş Kara +5 more
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An investigation of the protective effect of alpha+-thalassaemia against severe Plasmodium falciparum amongst children in Kumasi, Ghana [PDF]
Background: The alpha+-thalassaemias are the most common monogenic disorders of humans, characterised by microcytic and hypochromic anaemia. Their high frequency reflects selective advantage against death from Plasmodium falciparum malaria.
Opoku-Okrah, C., Opoku-Okrah, C.
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بررسی مولکولی جهش های غير حذفی ژن های آلفاگلوبين بيماران آلفا تالاسمی دراستان کرمانشاه [PDF]
, 2014 زمينه و هدف : آلفاتالاسمی يک بيماری تک ژنی با توارث اتوزومی مغلوب بوده و در جمعيت هايی با منشاء مديترانه ای و آسيای جنوب شرقی شايع می باشد. بررسی شيوع جهش های غير حذفی اين بيماری می تواند راهنمای مفيد و سريعی جهت پيش گيری، کنترل و تشخيص قبل از تولد اين ...
اكرمي پور, رضا +3 more
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Appropriate whole genome amplification and pathogenic loci detection can improve the accuracy of preimplantation genetic diagnosis for deletional α-thalassemia. [PDF]
Front Endocrinol (Lausanne), 2023 Lan Y +10 more
europepmc +1 more source
A comprehensive preimplantation genetic testing approach for SEA-type α-thalassemia by fluorescent gap-polymerase chain reaction combined with haplotype analysis. [PDF]
Front Genet, 2023 Wang J, Ma Y, Guo J, Li R, Zhou C, Xu Y.
europepmc +1 more source
Moyamoya syndrome with ruptured aneurysm in α-thalassemia: A case report. [PDF]
Exp Ther Med, 2022 Zhu J, Zhang M, Sun Y, Zhang X.
europepmc +1 more source
Journal of Associated Medical Sciences, 2018 Background: Thalassemia is common in Thailand. Knowing the prevalence of thalassemia carriers in married couples would lead to proper management of this disease.
Ekthong Limveeraprajak
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Analysis of genotype-phenotype correlation in patients with α-thalassemia from Fujian province, Southeastern China. [PDF]
J Clin Lab Anal, 2022 Pan Y +7 more
europepmc +1 more source
Prevalence of α-thalassemia 3.7 kb deletion in the adult population of Rio Grande do Norte, Brazil
Genetics and Molecular Biology, 2012 α-Thalassemia, arising from a defect in a-globin chain synthesis, is often caused by deletions involving one or both of the a-genes on the same allele. With the aim of investigating the prevalence of α-thalassemia 3.7 kb deletion in the adult population ...
Gustavo Henrique de Medeiros Alcoforado +7 more
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