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, 2022 From Volume 1 (2011) to Volume 11 (2021), Thalassemia Reports [...
Thalassemia Reports Editorial Office Thalassemia Reports Editorial Office
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Frontiers in Genetics, 2022 Background: Thalassemia is a common inherited hematological disease with genetic disorders characterized by imbalanced synthesis of the globin chains.
Jingxian Ding +5 more
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Alpha and beta-Thalassemia mutations in Hubei area of China
BMC Medical Genetics, 2020 Background Thalassemia is a group of inherited hemoglobic disorders resulting from defects in the synthesis of one or more of the hemoglobin chains, which is one of the most prevalent inherited disorders in southern China.
Yaowu Zhu +4 more
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Hematology, 2023 Background Thalassemia, a common autosomal hereditary blood disorder worldwide, mainly contains α- and β-thalassemia. The α-globin gene triplicates allele is harmless for carriers, but aggravates the phenotype of β-thalassemia.
Yujiao Chen +5 more
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Diagnostic Utility of a Multiplex PCR Assay in Detecting Common Mutations of the α-Globin Gene in α-Thalassemia. [PDF]
AnemiaAlpha-thalassemia is a hereditary hemoglobin disorder characterized by reduced or absent α-globin gene, and its severity is associated with the number of affected alleles.
Park SN, Roh J, Kim JT, Song MJ.
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Immunity to Pneumococcal Vaccine in Splenectomized β-Thalassemia Patients [PDF]
American Journal of Immunology, 2012 Problem statement: Splenectomy is accompanied by a lifelong risk of overwhelming post splenectomy infection, mainly caused by encapsulated bacteria such as Streptococcus pneumoniae. The mortality rate in those infected patients remains high. Therefore the pneumococcal polysaccharide vaccine has been recommended.
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Protein C and Protein S Levels in β-Thalassemia Major Patients in Erbil, Kurdistan Region
Cellular and Molecular Biology, 2020 Oxygen is transported in the blood through red blood cells and a protein called hemoglobin. The protein consists of two alpha and two beta chains. The lack of any of these chains is caused by the malfunction of the genes that produce them, and can lead to a genetic disease called thalassemia.
Tareefa Kakakhan, Hadi +2 more
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Highlights on the Luspatercept Treatment in Thalassemia
, 2023 Luspatercept has been shown to act as a ligand trap, selectively suppressing the deleterious effects of GDF11 that blocks terminal erythroid maturation, restoring normal erythroid differentiation and improving anemia in animal models of &beta ...
Yesim Aydinok
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Biosensors and Bioelectronics: X, 2023 A label-free electrochemical DNA biosensor based on electrochemical impedance spectroscopy (EIS) biosensor has been extensively developed for diagnosing human genetic diseases. However, its application has been limited to simulated target DNA. The aim of
Areenuch Thamwarokun +5 more
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A Comparison of Intelligence Quotient in Children with and without β-Thalassemia Major
Galen Medical Journal, 2015 Background: Thalassemia is the most common hemoglobinopathy worldwide. Children with β-thalassemia major have several risk factors for cognitive problems. The aim of this study is to evaluate intelligence quotient in children with β-thalassemia major and healthy counterparts using Wechsler Intelligence Scale.
Samaneh Homayouni Meymandi +2 more
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