Results 31 to 40 of about 1,044,639 (194)

A label-free electrochemical biosensor for the detection of alpha-thalassemia 1 (SEA deletion) carriers using screen-printed carbon electrodes

Biosensors and Bioelectronics: X, 2023
A label-free electrochemical DNA biosensor based on electrochemical impedance spectroscopy (EIS) biosensor has been extensively developed for diagnosing human genetic diseases. However, its application has been limited to simulated target DNA. The aim of
Areenuch Thamwarokun, Chollanot Kaset, Chanpen Karuwan, Wichayaporn Kamsong, Jirapat Attapong, Sirinart Chomean   +5 more
doaj   +1 more source

Diagnosis of patients with hemoglobinopathies including α-thalassemia in a laboratory with limited resources

Iraqi Journal of Hematology, 2020
BACKGROUND: Diagnosis of α-thalassemia can be challenging as it is clinically insignificant in the majority of patients who are presented with one or two α-gene deletion, it cannot be always suspected from the red cell indices, and the confirmatory tests
Abbas Hashim Abdulsalam, Subh Salim Al-Mudallal, Nidhal Karim Al-Rahal   +2 more
doaj   +1 more source

Epidemiological investigation of thalassemia in gestational age population of Dai nationality in Dehong Prefecture, Yunnan Province [PDF]

Jichu yixue yu linchuang, 2022
Objective To investigate the gene carrying rate,gene mutation type and hematological characteristics of thalassemia in Dai nationality population of Dehong Prefecture, Yunnan Province.
TENG Cong-cong, XU Yong-mei, TANG Shu-ping, LI Yong, YANG Yang, LONG Lan, ZHANG Jie
doaj   +1 more source

β-THALASSEMIA TRAIT MENGGUNAKAN ELEKTROFORESIS MIKROKAPILER

INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY, 2018
Thalassemia is a genetic disorder disease which spread in the different parts of the world, including Indonesia. The incidence of β-thalassemia trait in Indonesia is between 3−8%. The objective of this study is to know the incidence of β-thalassemia trait in studentswho performed medical check-up, which obtain by using capilary electrophoresis, to ...
Nuryanti Nuryanti, Ratna Akbari Ganie, Adi Koesoema Aman   +2 more
openaire   +2 more sources

Diagnostic Utility of a Multiplex PCR Assay in Detecting Common Mutations of the α-Globin Gene in α-Thalassemia. [PDF]

Anemia
Alpha-thalassemia is a hereditary hemoglobin disorder characterized by reduced or absent α-globin gene, and its severity is associated with the number of affected alleles.
Park SN, Roh J, Kim JT, Song MJ.
europepmc   +2 more sources

The hypercoagulation state among major β-thalassemia patients at H. Adam Malik Hospital, Medan, Indonesia

Bali Medical Journal, 2019
Background: Thalassemia is the most common hereditary blood disorder in the world and Indonesia. Major β-thalassemia is classified as Transfusion-Dependent Thalassemia (TDT). Specific changes in the composition of red cell membrane lipids and hemosiderosis may lead to hypercoagulation.
Jane Tetraulina Silitonga, Adi Koesoema Aman, Bidasari Lubis   +2 more
openaire   +1 more source

Effect of α(+)-thalassaemia on episodes of fever due to malaria and other causes: a community-based cohort study in Tanzania. [PDF]

, 2011
It is controversial to what degree α(+)-thalassaemia protects against episodes of uncomplicated malaria and febrile disease due to infections other than Plasmodium. In Tanzania, in children aged 6-60 months and height-for-age z-score < -1.5 SD (n = 612),
Veenemans, J., Veenemans, Jacobien, Mbugi Erasto V, Huub FJ Savelkoul, Savelkoul, H.F.J., Demir, Ayşe Y, Savelkoul, Huub FJ, Hans Verhoef, Baidjoe, Amrish Y, Esther JS Jansen, Amrish Y Baidjoe, Kraaijenhagen, Rob J, Jansen Esther JS, Veenemans Jacobien, Demir Ayşe Y, Mbugi, Erasto V, Rob J Kraaijenhagen, Baidjoe, A.Y., Verhoef, H., Verhoef Hans, Kraaijenhagen Rob J, Erasto V Mbugi, Jansen, Esther JS, Savelkoul Huub FJ, Ayşe Y Demir, Baidjoe Amrish Y, Jansen, E.J.S., Mbugi, E.V., Jacobien Veenemans, Verhoef, Hans, Demir, A.Y., Kraaijenhagen, R.J.   +31 more
core   +1 more source

Prevalence and Genetic Analysis of Thalassemia and Hemoglobinopathy in Different Ethnic Groups and Regions in Hainan Island, Southeast China

Frontiers in Genetics, 2022
Background: There are limited studies on the molecular profile of thalassemia in Hainan, the free trade island in China. Our aim was to reveal the prevalence and molecular mutation spectrum of thalassemia in different ethnic groups and regions of Hainan ...
Min Wang, Min Wang, Xiaozhuang Zhang, Xiaozhuang Zhang, Yubin Zhang, Yubin Zhang, Meifang Xiao, Meifang Xiao   +7 more
doaj   +1 more source

MOESM1 of A validated cellular biobank for β-thalassemia

, 2016
Additional file 1: Table S1. List of the subjects (patients and healthy subjects) present in the Thal-Biobank.
Cosenza, Lucia, Breda, Laura, Breveglieri, Giulia, Zuccato, Cristina, Finotti, Alessia, Lampronti, Ilaria, Borgatti, Monica, Chiavilli, Francesco, Gamberini, Maria, Satta, Stefania, Manunza, Laura, Martis, Franca, Moi, Paolo, Rivella, Stefano, Gambari, Roberto, Bianchi, Nicoletta   +15 more
openaire   +1 more source

MOESM2 of A validated cellular biobank for β-thalassemia

, 2016
Additional file 2: Table S2. HbF and HbA2 production in ErPC cultures from 14 β-thalassemia patients after 4 and 8 days differentiation.
Cosenza, Lucia, Breda, Laura, Breveglieri, Giulia, Zuccato, Cristina, Finotti, Alessia, Lampronti, Ilaria, Borgatti, Monica, Chiavilli, Francesco, Gamberini, Maria, Satta, Stefania, Manunza, Laura, Martis, Franca, Moi, Paolo, Rivella, Stefano, Gambari, Roberto, Bianchi, Nicoletta   +15 more
openaire   +1 more source