Results 41 to 50 of about 1,044,639 (194)

Study of discriminant factor M/H ratio in screening for β thalassemia trait

IP Journal of Diagnostic Pathology and Oncology, 2020
Introduction: Beta Thalassemia syndrome is a group of hereditary disorders characterized by genetic deficiency in the synthesis of beta globin chains located on chromosome 11. A major diagnostic challenge is to differentiate between mild microcytic hypochromic anaemia due to BTT from other causes such as iron deficiency (IDA), sideroblastic anaemia etc.
openaire   +2 more sources

Supplementary Material for: Analysis of hematological indices and splenectomy rates in 2,130 patients with Hemoglobin H diseases or β-thalassemia

, 2023
Introduction Splenomegaly and hypersplenism are common complications of thalassemia patients due to the excessive clearance of defective red blood cells from the spleen.
Shang H. (16810938), Ye Y. (3230418), Li P. (4157617), Xu X. (2878946), Qin L. (4762131), Zhang X. (3333504), Wang L. (3116751), Xiao B. (16810941), Li Y. (3218205), Zhang Y. (2828780)   +9 more
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Blood Pressure and Arterial Stiffness in Kenyan Adolescents With α+Thalassemia. [PDF]

, 2017
Background Recent studies have discovered that α‐globin is expressed in blood vessel walls where it plays a role in regulating vascular tone. We tested the hypothesis that blood pressure (BP) might differ between normal individuals and those with α ...
Khayeka-Wandabwa, C, Cruickshank, K, Odipo, E., Tendwa, M., Cruickshank, JK, Wamukoya, M, Muthumbi, E., Kyobutungi, C, Williams, T. N., Scott, John, Makale, J., Williams, TN, Wamukoya, M., Macharia, A., Ngomi, Nicholas N., Smeeth, L, Kapesa, S., Etyang, AO, Ngomi, N, Macharia, A, Cruickshank, J. K., Scott, A. G., Odipo, E, Khayeka, C., Muthumbi, E, Haregu, T, Scott, JAG, Kapesa, S, Haregu, T. N., Makale, J, Smeeth, L., Etyang, A. O., Tendwa, M, Kyobutungi, C., Odipo, Emily, Catherine Kyobutungi, Macharia, Alex, Esther Muthumbi, Emily Odipo, Scott, J. Anthony G., Muthumbi, Esther, Kyobutungi, Catherine, Williams, Thomas N., Wamukoya, Marylene, Johnstone Makale, Nicholas Ngomi, Etyang, Anthony O., Cruickshank, J. Kennedy, Khayeka-Wandabwa, Christopher, Sailoki Kapesa, Christopher Khayeka‐Wandabwa, Thomas N. Williams, Haregu, Tilahun, J. Kennedy Cruickshank, Khayeka‐wandabwa, Christopher, Kapesa, Sailoki, Etyang, Anthony O, Cruickshank, J Kennedy, Marylene Wamukoya, Tendwa, Metrine, Tilahun Haregu, Makale, Johnstone, Liam Smeeth, Scott, J Anthony G, Williams, Thomas N, J. Anthony G. Scott, Smeeth, Liam, Metrine Tendwa, Alex Macharia, Ngomi, Nicholas, Anthony O. Etyang   +70 more
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α-Thalassemia impairs the cytoadherence of Plasmodium falciparum-infected erythrocytes. [PDF]

, 2012
α-Thalassemia results from decreased production of α-globin chains that make up part of hemoglobin tetramers (Hb; α(2)β(2)) and affects up to 50% of individuals in some regions of sub-Saharan Africa.
Jeffrey R Keefer, Seidina A S Diakite, Diakite Mahamadou, Lopera-Mesa Tatiana M., Chanaki Amaratunga, Keefer Jeffrey R., Amaratunga Chanaki, Arie Takayuki, Doumbia Saibou, Tatiana M Lopera-Mesa, Mahamadou Diakite, Michael A Krause, Rick M Fairhurst, Diakite Seidina A. S., Takayuki Arie, Karim Traore, Saibou Doumbia, Drissa Konate, Krause Michael A., Fairhurst Rick M., Traore Karim, Konate Drissa   +21 more
core   +1 more source

Prevalence of B-Thalassemia Carriers Among a Cohort of University Students in Hawler Province of Iraqi Kurdistan

Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512), 2017
         A representative sample of a thousand volunteer university students was screened for evidence of thalassemia minor.Complete blood counts using automated blood cell analysers and blood smears were examined. Patients having anemia, abnormal red cell indices or morphological features of thalassemia minor like hypochromia, microcytosis, target ...
Abdulkadir A. Alnakshabandi, Huda A. Muhammad   +1 more
openaire   +3 more sources

Identification and molecular characterization of a novel 163 kb deletion: The Italian (ϵγδβ)⁰-thalassemia

, 2018
Objective and importance: To verify the presence of β-thalassemia in subjects showing hematologic phenotype of α-thalassemia, conduct normal molecular sequence analysis of the α-globin genes, and detect the absence of the most frequent α-thalassemia ...
Clelia Scarano (2879918), Sabrina Dembech (2879921), Francesca Del Vecchio Blanco (2879915), Romeo Prezioso (697049), Giovanna Cardiero (697046), Giuseppina Lacerra (697054)   +5 more
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Effect of Assorted Globin Haplotypes and α-Thalassemia on the Clinical Heterogeneity of Hb S-β-Thalassemia

, 2019
Hemoglobinopathies and thalassemias are the most commonly encountered monogenic disorders of blood in humans, posing a major genetic and public health problem round the globe.
Kiran R. Kharat (686460), Praveen K. Sahu (1846699), Preetinanda M. Dash (6021755), Ranjeet S. Mashon (6021761), Malay B. Mukherjee (6021764), Siris Patel (6021758)   +5 more
core   +1 more source

Genotypic distribution of thalassemia in pregnant women in Nanning, Guangxi, and its impact on pregnancy outcomes

Shanghai Jiaotong Daxue xuebao. Yixue ban
Objective·To investigate the genotypic distribution of thalassemia in pregnant women in Nanning, Guangxi, and its impact on pregnancy outcomes.Methods·A retrospective cohort study was conducted among 3 649 pregnant women enrolled from January 2021 to ...
Li Jing, Liang Xuxia, Wu Hua, Zhang Chun, Lu Yanqun, Zhang Jihong   +5 more
doaj   +1 more source

Diagram for the screening of hemoglobin variants, α/β-thalassemia and HPFH/δβ-thalassemia.

, 2013
Diagram for the screening of hemoglobin variants, α/β-thalassemia and HPFH/δβ-thalassemia.
Chun-Ping Lin (285488), Fen-Ting Huang (285491), Ri-Xin Zeng (285499), Di-Hong Wu (285495), Hui Yang (91136), Yuan Wang (14955), Li-Ye Yang (285504), Qiu-Qing Weng (285490), Min Lu (238723), Hua Yang (120668), Hui-Zhou Chen (285493), Long-Xu Xie (285502), Yue Huang (285485), Jun-Li Wang (285503), Fen Lin (285486), Juan-Juan Zhu (285501), Gui-Cai Li (285500), Min Lin (17652), Xiao-Fen Zhan (285487), Jing-Bo Zeng (285498), Ying-Fang Wen (285483), Jiao-Ren Wu (285484), Gui-Rong Liu (80139), Mei-Qiong Yao (285492), Qian Wang (32718), Hui-Tian Yang (285489), Lei Zheng (106363)   +26 more
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Association of α globin gene quadruplication and heterozygous β thalassemia in patients with thalassemia intermedia

Haematologica, 2009
Ten patients with thalassemia intermedia with variable severity and apparent simple heterozygosis for β0 39 C>T nonsense mutation were submitted to clinical, hematologic and molecular studies.
Maria Carla Sollaino, Maria Elisabetta Paglietti, Lucia Perseu, Nicolina Giagu, Daniela Loi, Renzo Galanello   +5 more
doaj   +1 more source