Results 41 to 50 of about 779,152 (196)

Thalassemia and Hemoglobin E in Southern Thai Blood Donors

Advances in Hematology, 2014
Thalassemia and hemoglobin E (Hb E) are common in Thailand. Individuals with thalassemia trait usually have a normal hemoglobin concentration or mild anemia. Therefore, thalassemic individuals who have minimum acceptable Hb level may be accepted as blood
Manit Nuinoon, Kwanta Kruachan, Warachaya Sengking, Dararat Horpet, Ubol Sungyuan   +4 more
doaj   +1 more source

Diagnosis of patients with hemoglobinopathies including α-thalassemia in a laboratory with limited resources

Iraqi Journal of Hematology, 2020
BACKGROUND: Diagnosis of α-thalassemia can be challenging as it is clinically insignificant in the majority of patients who are presented with one or two α-gene deletion, it cannot be always suspected from the red cell indices, and the confirmatory tests
Abbas Hashim Abdulsalam, Subh Salim Al-Mudallal, Nidhal Karim Al-Rahal   +2 more
doaj   +1 more source

Epidemiological investigation of thalassemia in gestational age population of Dai nationality in Dehong Prefecture, Yunnan Province [PDF]

Jichu yixue yu linchuang, 2022
Objective To investigate the gene carrying rate,gene mutation type and hematological characteristics of thalassemia in Dai nationality population of Dehong Prefecture, Yunnan Province.
TENG Cong-cong, XU Yong-mei, TANG Shu-ping, LI Yong, YANG Yang, LONG Lan, ZHANG Jie
doaj   +1 more source

Supplementary Material for: Analysis of hematological indices and splenectomy rates in 2,130 patients with Hemoglobin H diseases or β-thalassemia

, 2023
Introduction Splenomegaly and hypersplenism are common complications of thalassemia patients due to the excessive clearance of defective red blood cells from the spleen.
Shang H. (16810938), Ye Y. (3230418), Li P. (4157617), Xu X. (2878946), Qin L. (4762131), Zhang X. (3333504), Wang L. (3116751), Xiao B. (16810941), Li Y. (3218205), Zhang Y. (2828780)   +9 more
core   +1 more source

β-THALASSEMIA TRAIT MENGGUNAKAN ELEKTROFORESIS MIKROKAPILER

INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY, 2018
Thalassemia is a genetic disorder disease which spread in the different parts of the world, including Indonesia. The incidence of β-thalassemia trait in Indonesia is between 3−8%. The objective of this study is to know the incidence of β-thalassemia trait in studentswho performed medical check-up, which obtain by using capilary electrophoresis, to ...
Nuryanti Nuryanti, Ratna Akbari Ganie, Adi Koesoema Aman   +2 more
openaire   +2 more sources

A particular focus on the prevalence of α-thalassemia and β-thalassemia among pregnant women in Changsha County, Hunan Province. [PDF]

Front Genet
BackgroundThalassemia is a inherited monogenic blood disorder and more prevalent in southern China. In this study, Our aim was to elucidate the molecular spectrum and phenotypic features of thalassemia in pregnant women in Changsha County.MethodsNext ...
Xia Y, Huang C, Yang M, Zhang M, Lu Y.
europepmc   +2 more sources

Multi-center transferability of a breath-hold T2 technique for myocardial iron assessment. [PDF]

, 2008
Background: Cardiac iron overload is the leading cause of death in thalassemia major and is usually assessed using myocardial T2* measurements. Recently a cardiovascular magnetic resonance (CMR) breath-hold T2 sequence has been developed as a possible ...
Tan, RS, Tan Ru, Chan, G.C.F, He, T, Fogel Mark A, Firmin David N, Au, W-Y, Pennell, Dudley J., Chan, GCF, Fogel, MA, Lam, W.M, Aydinok, Y, Chu, WCW, He, Taigang, Cohen, AR, Ng, I, Chu Winnie CW, Cohen, Alan R., Pennell, DJ, Pennell Dudley J, Firmin, D.N, Chu, W.C.W, Biceroglu, S, Fogel, M.A, Tan, R.S, Lam, WM, Chan Godfrey CF, Lam Wynnie M, Firmin, David N., Biceroglu Selen, Aydinok Yesim, Aydinok, Yesim, Firmin, DN, Kirk, Paul, Fogel, Mark A., Pennell, D.J, Ng Ivy, Kirk, P, Au, Wing-Yan, Tan, Ru San, Au, WY, He Taigang, Kirk Paul, Chan, GC, Biceroglu, Selen, Cohen, A.R, Au Wing-Yan, Chu, Winnie C. W., Chu, WC, Au, W.-Y, Lam, Wynnie M., Cohen Alan R, Ng, Ivy, Chan, Godfrey C. F.   +53 more
core   +1 more source

Study of discriminant factor M/H ratio in screening for β thalassemia trait

IP Journal of Diagnostic Pathology and Oncology, 2020
Introduction: Beta Thalassemia syndrome is a group of hereditary disorders characterized by genetic deficiency in the synthesis of beta globin chains located on chromosome 11. A major diagnostic challenge is to differentiate between mild microcytic hypochromic anaemia due to BTT from other causes such as iron deficiency (IDA), sideroblastic anaemia etc.
openaire   +2 more sources

Prevalence and Genetic Analysis of Thalassemia and Hemoglobinopathy in Different Ethnic Groups and Regions in Hainan Island, Southeast China

Frontiers in Genetics, 2022
Background: There are limited studies on the molecular profile of thalassemia in Hainan, the free trade island in China. Our aim was to reveal the prevalence and molecular mutation spectrum of thalassemia in different ethnic groups and regions of Hainan ...
Min Wang, Min Wang, Xiaozhuang Zhang, Xiaozhuang Zhang, Yubin Zhang, Yubin Zhang, Meifang Xiao, Meifang Xiao   +7 more
doaj   +1 more source

The hypercoagulation state among major β-thalassemia patients at H. Adam Malik Hospital, Medan, Indonesia

Bali Medical Journal, 2019
Background: Thalassemia is the most common hereditary blood disorder in the world and Indonesia. Major β-thalassemia is classified as Transfusion-Dependent Thalassemia (TDT). Specific changes in the composition of red cell membrane lipids and hemosiderosis may lead to hypercoagulation.
Jane Tetraulina Silitonga, Adi Koesoema Aman, Bidasari Lubis   +2 more
openaire   +1 more source