Results 21 to 30 of about 1,044,639 (194)
Frontiers in Nutrition, 2022 BackgroundThere are limited studies on iron-deficiency anemia (IDA) in carriers of various thalassemia genotypes. However, for pregnant women (PW) with high iron demand, ignoring the phenomenon of carrying the thalassemia genes combined with IDA may lead
Min Wang +6 more
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Correlation between Serum Ferritin, Serum Cystatin C, and Renal Function in Children with β Thalassemia Major [PDF]
Majalah Kedokteran Bandung, 2019 Renal dysfunction caused by iron overload is characterized by an increase in ferritin and cystatin C levels. The objective of this study was to determine the correlation between ferritin, cystatin C, and renal function in children with β thalassemia major.
Suci Saptyuni Permadi +2 more
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Frontiers in Genetics, 2022 Background: Thalassemia is a common inherited hematological disease with genetic disorders characterized by imbalanced synthesis of the globin chains.
Jingxian Ding +5 more
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Immunity to Pneumococcal Vaccine in Splenectomized β-Thalassemia Patients [PDF]
American Journal of Immunology, 2012 Problem statement: Splenectomy is accompanied by a lifelong risk of overwhelming post splenectomy infection, mainly caused by encapsulated bacteria such as Streptococcus pneumoniae. The mortality rate in those infected patients remains high. Therefore the pneumococcal polysaccharide vaccine has been recommended.
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Protein C and Protein S Levels in β-Thalassemia Major Patients in Erbil, Kurdistan Region
Cellular and Molecular Biology, 2020 Oxygen is transported in the blood through red blood cells and a protein called hemoglobin. The protein consists of two alpha and two beta chains. The lack of any of these chains is caused by the malfunction of the genes that produce them, and can lead to a genetic disease called thalassemia.
Tareefa Kakakhan, Hadi +2 more
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Alpha and beta-Thalassemia mutations in Hubei area of China
BMC Medical Genetics, 2020 Background Thalassemia is a group of inherited hemoglobic disorders resulting from defects in the synthesis of one or more of the hemoglobin chains, which is one of the most prevalent inherited disorders in southern China.
Yaowu Zhu +4 more
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Hematology, 2023 Background Thalassemia, a common autosomal hereditary blood disorder worldwide, mainly contains α- and β-thalassemia. The α-globin gene triplicates allele is harmless for carriers, but aggravates the phenotype of β-thalassemia.
Yujiao Chen +5 more
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A Comparison of Intelligence Quotient in Children with and without β-Thalassemia Major
Galen Medical Journal, 2015 Background: Thalassemia is the most common hemoglobinopathy worldwide. Children with β-thalassemia major have several risk factors for cognitive problems. The aim of this study is to evaluate intelligence quotient in children with β-thalassemia major and healthy counterparts using Wechsler Intelligence Scale.
Samaneh Homayouni Meymandi +2 more
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Variable Clinical Phenotypes of α-Thalassemia Syndromes [PDF]
, 2009 Genetic mutations of the α genes are common worldwide. In Asia and particularly Southeast Asia, they can result in clinically significant types of α-thalassemia, namely hemoglobin (Hb) H disease and Hb Bart's hydrops fetalis.
Sylvia Titi Singer
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Orphanet Journal of Rare Diseases, 2022 Background To evaluate whether the quantification of fetal hemoglobin (Hb) Bart’s is useful for differentiation of α-thalassemia syndromes in the fetus and to characterize the fetal anemia associated with fetal α-hemoglobinopathy.
Kritsada Singha +6 more
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