Results 21 to 30 of about 965,280 (210)

Effect of α(+)-Thalassaemia on Episodes of Fever due to Malaria and Other Causes: A Community-Based Cohort Study in Tanzania. [PDF]

, 2011
It is controversial to what degree α(+)-thalassaemia protects against episodes of uncomplicated malaria and febrile disease due to infections other than Plasmodium. In Tanzania, in children aged 6-60 months and height-for-age z-score < -1.5 SD (n = 612),
Veenemans, J., Veenemans, Jacobien, Mbugi Erasto V, Huub FJ Savelkoul, Savelkoul, H.F.J., Demir, Ayşe Y, Savelkoul, Huub FJ, Hans Verhoef, Baidjoe, Amrish Y, Esther JS Jansen, Amrish Y Baidjoe, Kraaijenhagen, Rob J, Jansen Esther JS, Savelkoul, Huub F J, Veenemans Jacobien, Demir Ayşe Y, Mbugi, Erasto V, Rob J Kraaijenhagen, Savelkoul, H.F.J, Baidjoe, A.Y., Verhoef, H., Verhoef Hans, Kraaijenhagen Rob J, Erasto V Mbugi, Jansen, Esther JS, Savelkoul Huub FJ, Ayşe Y Demir, Baidjoe Amrish Y, Jansen, E.J.S., Mbugi, E.V., Jacobien Veenemans, Verhoef, Hans, Jansen, Esther J S, Demir, A.Y., Kraaijenhagen, R.J.   +34 more
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The prevalence and genetic disorders spectrum of thalassemia among breast cancer patients in Jiangxi province, China

Frontiers in Genetics, 2022
Background: Thalassemia is a common inherited hematological disease with genetic disorders characterized by imbalanced synthesis of the globin chains.
Jingxian Ding, Zhaohui Huang, Xiaoliu Jiang, Qingge Li, Yali Cao, Yonghong Guo   +5 more
doaj   +1 more source

Highlights on the Luspatercept Treatment in Thalassemia

, 2023
Luspatercept has been shown to act as a ligand trap, selectively suppressing the deleterious effects of GDF11 that blocks terminal erythroid maturation, restoring normal erythroid differentiation and improving anemia in animal models of &beta ...
Yesim Aydinok
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Immunity to Pneumococcal Vaccine in Splenectomized β-Thalassemia Patients [PDF]

American Journal of Immunology, 2012
Problem statement: Splenectomy is accompanied by a lifelong risk of overwhelming post splenectomy infection, mainly caused by encapsulated bacteria such as Streptococcus pneumoniae. The mortality rate in those infected patients remains high. Therefore the pneumococcal polysaccharide vaccine has been recommended.
openaire   +1 more source

Protein C and Protein S Levels in β-Thalassemia Major Patients in Erbil, Kurdistan Region

Cellular and Molecular Biology, 2020
Oxygen is transported in the blood through red blood cells and a protein called hemoglobin. The protein consists of two alpha and two beta chains. The lack of any of these chains is caused by the malfunction of the genes that produce them, and can lead to a genetic disease called thalassemia.
Tareefa Kakakhan, Hadi, Nawsherwan Sadiq, Mohammad, Saran Abdulqadir, Nooruldin   +2 more
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Alpha and beta-Thalassemia mutations in Hubei area of China

BMC Medical Genetics, 2020
Background Thalassemia is a group of inherited hemoglobic disorders resulting from defects in the synthesis of one or more of the hemoglobin chains, which is one of the most prevalent inherited disorders in southern China.
Yaowu Zhu, Na Shen, Xiong Wang, Juan Xiao, Yanjun Lu   +4 more
doaj   +1 more source

Case report: Identification of a novel triplication of alpha-globin gene by the third-generation sequencing: pedigree analysis and genetic diagnosis

Hematology, 2023
Background Thalassemia, a common autosomal hereditary blood disorder worldwide, mainly contains α- and β-thalassemia. The α-globin gene triplicates allele is harmless for carriers, but aggravates the phenotype of β-thalassemia.
Yujiao Chen, Tiantian Xie, Minhui Ma, Juan Yang, Yihang Lv, Xudong Dong   +5 more
doaj   +1 more source

How early can myocardial iron overload occur in Beta thalassemia major? [PDF]

, 2014
BACKGROUND: Myocardial siderosis is the most common cause of death in patients with beta thalassemia major(TM). This study aimed at investigating the occurrence, prevalence and severity of cardiac iron overload in a young Chinese population with beta TM.
Gaohui Yang, Pan Hongfei, He, T, Lai, Y, Peng, P, Liu Rongrong, Long, X, Taigang He, Tan Shaohong, Liu, R, Hongfei Pan, Yang Weijia, Xingjiang Long, Rongrong Liu, Lai Yongrong, Yang Gaohui, He Taigang, Weijia Yang, Yang, G, Xinhua Zhang, Tan, S, Liling Long, Anderson Lisa, Lisa Anderson, Long Xingjiang, Yang, W, Zhang, X, Anderson, L, Peng Peng, Yongrong Lai, Zhang Xinhua, Long Liling, Pan, H, Shaohong Tan, Long, L   +34 more
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Publisher’s Note: Page Numbers Changed to Article Numbers for Articles Published in Thalassemia Reports Volumes 1–11

, 2022
From Volume 1 (2011) to Volume 11 (2021), Thalassemia Reports [...
Thalassemia Reports Editorial Office Thalassemia Reports Editorial Office
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A Comparison of Intelligence Quotient in Children with and without β-Thalassemia Major

Galen Medical Journal, 2015
Background: Thalassemia is the most common hemoglobinopathy worldwide. Children with β-thalassemia major have several risk factors for cognitive problems. The aim of this study is to evaluate intelligence quotient in children with β-thalassemia major and healthy counterparts using Wechsler Intelligence Scale.
Samaneh Homayouni Meymandi, Sayed Hamid Seyednezhad-Golkhatmi, Mandana Homayouni Meymandi   +2 more
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