Results 21 to 30 of about 779,152 (196)

Molecular Spectrum, Ethnic and Geographical Distribution of Thalassemia in the Southern Area of Hainan, China

Frontiers in Pediatrics, 2022
BackgroundThalassemia is one of the most common genetic diseases in southern China. Accurate population frequency data regarding the occurrence and distribution of thalassemia are important for designing appropriate prevention strategies for thalassemia.
Ying Yu, Chunjiao Lu, Ying Gao, Cuiyun Li, Dongxue Li, Jie Wang, Jie Wang, Hui Wei, Zhaohui Lu, Zhaohui Lu, Guoling You, Guoling You   +11 more
doaj   +1 more source

Molecular Characterization of α- and β-Thalassaemia Among Children From 1 to 10 Years of Age in Guangxi, A Multi-Ethnic Region in Southern China

Frontiers in Pediatrics, 2021
Background: Thalassemia is one of the most common genetic diseases in southern China. Howerver, population in different regions or different population has their own spectrums of thalassemia.
Sheng He, Dongming Li, Shang Yi, Xiuning Huang, Chaofan Zhou, Biyan Chen, Yangjin Zuo, Li Lin, Faqin Chen, Hongwei Wei   +9 more
doaj   +1 more source

THE CORRELATION OF β/α MRNA RATIO WITH CLINICAL AND HEMATOLOGICAL PARAMETERS IN PATIENTS WITH β-THALASSEMIA SYNDROME

The Iraqi Journal of Medical Sciences, 2022
Background: Thalassemias are a group of genetically transmitted blood diseases characterized by defects in the production of α- or β-chains of hemoglobin called α-thalassemia and β-thalassemia, respectively.
May H. Yousif, Hind S. Al-Mamoori
doaj   +1 more source

Prevalence and molecular characterization of common thalassemia among people of reproductive age in the border area of Guangxi-Yunnan-Guizhou province in Southwestern China

Hematology, 2022
Objectives: Thalassemia, the most common global monogenetic disorder, is highly prevalent in southern China. Epidemiological and molecular characterization of thalassemia is important for designing appropriate prevention strategies in high-risk areas ...
GuiDan Xu, ChunFang Wang, JunLi Wang, Min Lin, ZhengYi Chang, JuHua Liang, XiaoHao Chen, ShiMao Zhong, XueJuan Nong, WuJun Wei, YiBin Deng   +10 more
doaj   +1 more source

Investigating the level of Hba1c and insulin level in β-thalassemia patients

MEDISAINS: Jurnal Ilmiah Ilmu-Ilmu Kesehatan, 2023
Background: β-thalassemia is an inherited blood disorder characterized by reduced or no synthesis of β globin chain, resulting in chronic anemia, so blood transfusion is required as curative therapy. Repeated blood transfusions lead to iron overload that can lead to multiple organ damage, including pancreatic organs.Objective: This study aimed to ...
Husnan Mujiburrahman, Qodri Santosa, Joko Setyono, Nendyah Roestijawati, Lantip Rujito   +4 more
openaire   +2 more sources

Vitamin D, Calcium and Phosphor in Patients with β-Thalassemia Major [PDF]

INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY, 2019
There has been many reports that patients with β-thalassemia major have bone problems such as thinning of the bone, bone fragility and pathological fractures. For so many years it was believed that the bone problems is mainly caused by marrow expansion due to compenstation of the bone marrow to handle the chronic anaemia and hiypoxia in β-thalassemia
Ade Hariza Harahap, Bidasari Lubis, Herman Hariman   +2 more
openaire   +1 more source

Epidemiology of thalassemia among the hill tribe population in Thailand.

PLoS ONE, 2021
BackgroundThalassemia is a severe disease that occurs due to abnormalities in hemoglobin genes. Various genetic factors in different populations lead to different clinical manifestations of thalassemia disease, particularly among people who have a long ...
Tawatchai Apidechkul, Fartima Yeemard, Chalitar Chomchoei, Panupong Upala, Ratipark Tamornpark   +4 more
doaj   +1 more source

Molecular Epidemiology and Hematologic Characterization of Thalassemia in Guangdong Province, Southern China

Clinical and Applied Thrombosis/Hemostasis, 2022
Introduction: About 2% of the population in the world are carriers of the thalassemia gene. Thalassemia is highly prevalent in Southern China, and traditional clinical testing methods would cause missed diagnosis of partial static thalassemia.
Jiajia Xian MD, Yanchao Wang MD, Jianchun He MD, Shaoying Li MD, Wenzhi He MD, Xiaoyan Ma MD, Qing Li PhD   +6 more
doaj   +1 more source

Prevalence of iron-deficiency anemia in pregnant women with various thalassemia genotypes: Thoughts on iron supplementation in pregnant women with thalassemia genes

Frontiers in Nutrition, 2022
BackgroundThere are limited studies on iron-deficiency anemia (IDA) in carriers of various thalassemia genotypes. However, for pregnant women (PW) with high iron demand, ignoring the phenomenon of carrying the thalassemia genes combined with IDA may lead
Min Wang, Xiaozhuang Zhang, Yanhong Zhao, Yubin Zhang, Yan Lin, Meifang Xiao, Ling Li   +6 more
doaj   +1 more source

Effect of α(+)-Thalassaemia on Episodes of Fever due to Malaria and Other Causes: A Community-Based Cohort Study in Tanzania. [PDF]

, 2011
It is controversial to what degree α(+)-thalassaemia protects against episodes of uncomplicated malaria and febrile disease due to infections other than Plasmodium. In Tanzania, in children aged 6-60 months and height-for-age z-score < -1.5 SD (n = 612),
Veenemans, J., Veenemans, Jacobien, Mbugi Erasto V, Huub FJ Savelkoul, Savelkoul, H.F.J., Demir, Ayşe Y, Savelkoul, Huub FJ, Hans Verhoef, Baidjoe, Amrish Y, Esther JS Jansen, Amrish Y Baidjoe, Kraaijenhagen, Rob J, Jansen Esther JS, Savelkoul, Huub F J, Veenemans Jacobien, Demir Ayşe Y, Mbugi, Erasto V, Rob J Kraaijenhagen, Savelkoul, H.F.J, Baidjoe, A.Y., Verhoef, H., Verhoef Hans, Kraaijenhagen Rob J, Erasto V Mbugi, Jansen, Esther JS, Savelkoul Huub FJ, Ayşe Y Demir, Baidjoe Amrish Y, Jansen, E.J.S., Mbugi, E.V., Jacobien Veenemans, Verhoef, Hans, Jansen, Esther J S, Demir, A.Y., Kraaijenhagen, R.J.   +34 more
core   +1 more source