Results 141 to 150 of about 902,322 (261)

Біоінформаційний пошук послідовностей генів, що кодують тубуліни у геномі льону

Фактори експериментальної еволюції організмів, 2014
Aims. Flax (Linum usitatissimum) is the most important industrial crop that covers human needs in the cellulose-rich fibers of high quality. Molecular mechanisms of cellulose biosynthesis are still poorly understood, but a basic component consisting of ...
Г. Я. Баєр, М. О. Пидюра, Я. В. Пірко, А. І. Ємець, Я. Б. Блюм   +4 more
doaj  

Genome-wide identification and evolution of the tubulin gene family in Camelina sativa

BMC Genomics
Background Tubulins play crucial roles in numerous fundamental processes of plant development. In flowering plants, tubulins are grouped into α-, β- and γ-subfamilies, while α- and β-tubulins possess a large isotype diversity and gene number variations ...
Rostyslav Y. Blume, Anastasiia M. Rabokon, Mykola Pydiura, Alla I. Yemets, Yaroslav V. Pirko, Yaroslav B. Blume   +5 more
doaj   +1 more source

Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair

Advanced Science, EarlyView.
Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li, Xin Xing, Beicheng Du, Myles Zhou, Austin Z. Chen, Mary Archer, Chunbao Rao, Manyu Zhu, Masnsen Cherief, Aaron W. James   +9 more
wiley   +1 more source

Tubulin-G protein interaction: The dynamic role of tubulin in the regulation of the neuronal adenylyl cyclase.

, 1990
Tubulin-G protein interaction: The dynamic role of tubulin in the regulation of the neuronal adenylyl ...
Nan. Wang (7984148)
core  

The effect of PRRSV and HDAC6 overexpression on α-tubulin acetylation.

, 2017
Kinetic analysis of JXA1-induced α-tubulin acetylation in MARC-145 cells (A) and in untreated cells (B). Kinetic analysis of JXA1-induced α-tubulin acetylation in PAMs (C) and in untreated cells (D). Kinetic analysis of JXA1-induced α-tubulin acetylation
Tianyu Lu (3615449), Kegong Tian (30834), Lin Liu (74495), Zhiyuan Song (553541), Meng Wang (124646), Qiuyan Li (526038), Ning Li (45258), Zhiguo Li (431917)   +7 more
core   +1 more source

Development of a Human 3D Immune‐Competent Neurovascular Model Enabling Time‐Resolved Monitoring of Neuroinflammatory Dynamics and Neuroimmune Interactions

Advanced Science, EarlyView.
Neuroinflammation alters blood–brain barrier integrity and contributes to neurological disorders, yet existing models lack human immune complexity. This study presents a 3D, immune‐responsive platform that reconstructs key neurovascular components and enables real‐time monitoring.
Pavlo Gordiichuk, Jing Bai, Olurotimi A. Bolonduro, Andrew M. Silverman, Robert Madison Green, Jason H. Lasser, Paul W. Fleming, Lishomwa C. Ndhlovu, James F. Saunders, Dmitry Shvartsman   +9 more
wiley   +1 more source

The Anticancer Natural Product Pironetin Selectively Targets Lys352 of α-Tubulin

, 2004
Pironetin is a potent inhibitor of tubulin assembly and arrests cell cycle progression in M phase. Analyses of its structure-activity relationships suggested that pironetin covalently binds tubulin.
Osada, Hiroyuki, Watanabe, Hiroyuki, Tada, Yukio, Nishikawa, Kiyohiro, Nakayama, Hiroshi, Kitahara, Takeshi, Asao, Tetsuji, Takio, Koji, Watanabe, Hidenori, Usui, Takeo, Kanoh, Naoki, Kondoh, Masuo   +11 more
core   +1 more source

Spatiotemporal Control of Formation of Dynamic Protein Fiber Assemblies via Photophysical Effects of a Focused Laser Beam

Advanced Science, EarlyView.
Tightly focused laser irradiation can accumulate tubulin proteins at/around the laser focus, which leads to the formation of highly ordered microtubule assemblies. The assemblies can exhibit various dynamic behaviors such as radial motion, bundling, and flagella‐like rotation with motor protein and chemical energy, highlighting as a unique tool for ...
Hiroshi Y. Yoshikawa, Ren Shirata, Takuya Takeshige, Riki Yoshida, Fumika Kiryu, Kei Takano, Shuma Matsumoto, Reiji Kawanami, Natsumi Sawada, Chi‐Shiun Wu, Yang‐Hsin Shih, Hiromasa Niinomi, Takahisa Matsuzaki, Seiichiro Nakabayashi, Tomoaki Matsuura, Teruki Sugiyama, Ryuzo Kawamura   +16 more
wiley   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source

Brown Adipocyte Sheets Alleviate Myocardial Ischemia–Reperfusion Injury Through NRG4–ErbB4–Dependent Ferroptosis Inhibition

Advanced Science, EarlyView.
Brown adipocyte sheets are engineered to protect the heart against myocardial ischemia–reperfusion injury by restraining ferroptosis. Upon transplantation onto the cardiac surface, they improve cardiac function, limit infarction and fibrosis, and enhance angiogenesis.
Lifu Sun, Yuting Liu, Jingbo Zhang, Takuji Kawamura, Junjun Li, Li Liu, Shigeru Miyagawa   +6 more
wiley   +1 more source