Results 181 to 190 of about 902,322 (261)

Tubulin isotype regulation maintains asymmetric requirement for α-tubulin over β-tubulin. [PDF]

J Cell Biol, 2023
Wethekam LC, Moore JK.
europepmc   +1 more source

Establishment of Interspecies Somatic Cell Nuclear Transfer and Transgene‐Free Inducible Pluripotent Stem Cells for Versatile Conservation of the Germplasm Resource of Wild Boar

Animal Research and One Health, EarlyView.
Conserving genetic material and even increasing genetic diversity is critical. To conduct the conservation of wild boar germplasm resources, we have successfully obtained healthy cloned wild boars for the first time using interspecies somatic cell nuclear transfer and established transgene‐free iPSCs that can be used to conduct iterative rounds of gene
Chen Gao, Xinyi Zhou, Shigang Gu, Jianbo Li, Jing Wang, Yurong Zhang, Wenxuan Zhao, Xinhua Wei, Liting Lu, Quanmin Zhao, Yongye Huang, Dawei Yu   +11 more
wiley   +1 more source

Peptides Derived from α-Tubulin Induce Functional T Regulatory Cells. [PDF]

Int J Mol Sci
Fiyouzi T, Subiza JL, Lafuente EM, Reche PA.   +3 more
europepmc   +1 more source

The role of α-tubulin tyrosination in controlling the structure and function of hippocampal neurons. [PDF]

Front Mol Neurosci, 2022
Hosseini S, van Ham M, Erck C, Korte M, Michaelsen-Preusse K.   +4 more
europepmc   +1 more source

Dietary Mannan‐Rich Fractions Attenuate Weaning Stress in Piglets via Modulating Gut Microbiota and TLR5/NF‐κB Signaling

Animal Research and One Health, EarlyView.
This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu, Yiwei Sun, Kun Cai, Pingli He, Gang Lin, Zengkai Qi, Hu Liu, Junshu Yan, Ning Ma   +8 more
wiley   +1 more source

Pan-cancer Myc modulator that targets Myc-α-tubulin interaction to drive selective mitotic catastrophe. [PDF]

Sci Rep
Teitel J, Farah M, Dziubinski ML, Lee P, White A, Sobeck A, Colina J, Takyi-Williams J, Wen B, Nurmemmedov E, Babic I, Monteiro da Rocha A, Bedi K, Robida A, McIntyre G, Hotta T, Lin Y, Sekhar SC, Ohi R, DiFeo A.   +19 more
europepmc   +1 more source

Hydrogen Peroxide Induces α-Tubulin Detyrosination and Acetylation and Impacts Breast Cancer Metastatic Phenotypes. [PDF]

Cells, 2023
Stemberger MB, Ju JA, Thompson KN, Mathias TJ, Jerrett AE, Chang KT, Ory EC, Annis DA, Mull ML, Gilchrist DE, Vitolo MI, Martin SS.   +11 more
europepmc   +1 more source

Disulfide Bond–Modified Proteomics Reveals the Effects of Riboflavin on Protein Folding Dynamics

Animal Research and One Health, EarlyView.
Riboflavin deficiency impairs oxidative protein folding, causing ER misfolded protein accumulation, CHOP activation, and apoptosis, revealing a role of riboflavin in proteostasis. ABSTRACT Riboflavin is a crucial micronutrient essential for maintaining cellular homeostasis, acting as an important precursor for flavoproteins that utilize flavin ...
Bo Zhang, Shuisheng Hou, Jing Tang
wiley   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

Unveiling the Possible Oryzalin-Binding Site in the α-Tubulin of Toxoplasma gondii. [PDF]

ACS Omega, 2022
Aguayo-Ortiz R, Dominguez L.
europepmc   +1 more source