Results 71 to 80 of about 6,855,939 (294)

α-Lactosylceramide Protects Against iNKT-Mediated Murine Airway Hyperreactivity and Liver Injury Through Competitive Inhibition of Cd1d Binding. [PDF]

, 2019
Invariant natural killer T (iNKT) cells, which are activated by T cell receptor (TCR)-dependent recognition of lipid-based antigens presented by the CD1d molecule, have been shown to participate in the pathogenesis of many diseases, including asthma and ...
Chang, Ya-Jen, Chi, Po-Yu, Gervay-Hague, Jacquelyn, Han, Yun-Chiann, Hsieh, Hsiao-Wu, Kao, Hsien-Neng, Lai, Alan Chuan-Ying, Thio, Christina Li-Ping   +7 more
core  

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Effects of dietary vitamin E and vitamin C supplementation on the level of α-tocopherol and L-ascorbic acid in muscle and on the antioxidative status and meat quality of pigs

Czech Journal of Animal Science, 2005
In total thirty pigs (Slovak Meaty) defined by DNA based test as not susceptible to malignant hyperthermia (non-mutant on RYR1) were used in the experiment.
R. Lahučký, I. Bahelka, K. Novotná, K. Vašíčková   +3 more
doaj   +1 more source

On approximation f by (α,β,γ)-Baskakov Operators

Journal of Al-Qadisiyah for Computer Science and Mathematics, 2017
  In the present paper, we study some application properties of the approximation for the sequences  and   . These sequences depend on the arbitrary (but fixed) parameters  and . Here, we study the effect of these parameters on tends speed of the two families of operators  and  and the CPU times which are occurring on the approximation by a choosing ...
openaire   +2 more sources

Γ-(,δ)-Derivation on Semi-Group Ideals in Prime Γ-Near-Ring

Iraqi Journal of Science, 2020
The main purpose of this paper is to investigate some results. When h is  -( ,δ) – Derivation on prime Γ-near-ring G and K is a nonzero semi-group ideal of G, then G is commutative .
Hiba A. Ahmed, Abdulrahman H. Majeed
openaire   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Formation of α-hydroxycarbonyl and α-dicarbonyl compounds during degradation of monosaccharides

Czech Journal of Food Sciences, 2007
The formation of α-hydroxycarbonyl and α-dicarbonyl compounds from monosaccharides (glucose, fructose, arabinose, glyceraldehyde, and 1,3-dihydroxyacetone) was studied in three different model systems comprising an aqueous and alkaline solution of ...
Ondřej Novotný, Karel Cejpek, Jan Velíšek   +2 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Influence of growing area, plant age, and virus infection on the contents of hop secondary metabolites

Czech Journal of Food Sciences, 2012
Hops and hop products (pellets and extracts) belong to the major raw materials employed in brewing industry. Many effects such as the growing area, hop plant age, and virus infection influence the contents of the brewing-important hop secondary ...
Lukáš JELÍNEK, Monika DOLEČKOVÁ, Marcel KARABÍN, Tereza HUDCOVÁ, Blanka KOTLÍKOVÁ, Pavel DOSTÁLEK   +5 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source