Results 81 to 90 of about 7,298,112 (344)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Influence of growing area, plant age, and virus infection on the contents of hop secondary metabolites

Czech Journal of Food Sciences, 2012
Hops and hop products (pellets and extracts) belong to the major raw materials employed in brewing industry. Many effects such as the growing area, hop plant age, and virus infection influence the contents of the brewing-important hop secondary ...
Lukáš JELÍNEK, Monika DOLEČKOVÁ, Marcel KARABÍN, Tereza HUDCOVÁ, Blanka KOTLÍKOVÁ, Pavel DOSTÁLEK   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Quality of wheat germ oil obtained by cold pressing and supercritical carbon dioxide extraction

Czech Journal of Food Sciences, 2013
Laboratory-prepared wheat germ oil was obtained by cold pressing and supercritical CO2 extraction. The main objective was to compare the quality of both oil samples obtained, with emphasis on their fatty acids compositions and tocopherol contents.
Mehmet M. Özcan, Antonella Rosa, Maria A. Dessi, Bruno Marongiu, Alessandra Piras, Fahad Y. I. AL-Juhaimi   +5 more
doaj   +1 more source

Co-administration of vitamin E and selenium in vivo and in vitro ameliorates the toxic effects caused by ivermection and doramectin

Veterinární Medicína, 2020
Avermectins are used in animals and humans for their broad-spectrum effects against parasites causing cytotoxicity and damage to the cellular DNA. In this study, we examined the toxicological changes of ivermectin (IVM) and doramectin (DME) with or ...
Ahmed Ezzat Ahmed, Mohammed A. Al-Kahtani, Atef M. Khalil, Ali S. Alshehri, Ashraf A. Elghoneimy, Serag Eldin I. Elbehairi, Mohammad Y. Alfaifi, Ali A. Shati, Kareem S. Morsy, Mohammed A. Alshehri, Haitham I. El-Mekkawy, Ahmed A. Elmansi   +11 more
doaj   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Flaxseed varieties: composition and influence on the growth of probiotic microorganisms in milk

Czech Journal of Food Sciences, 2017
The influence of flaxseed variety composition on probiotics (Lactobacillus acidophilus, Lb. helveticus, Bifidobacterium sp.) was determined. The varieties were added into milk in four forms: whole seed, ground seed, meal, and oil. The fermentation of all
Jana Smolová, Irena Němečková, Marcela Klimešová, Zdeněk Švandrlík, Marie Bjelková, Vladimír Filip, Jan Kyselka   +6 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Προς τους γονείς…, για τους γονείς… [PDF]

, 2006
Το άρθρο αυτό εστιάζεται στις ανάγκες και στις προσδοκίες των γονέων παιδιών με διαταραχές του φάσματος του αυτισμού από τους επαγγελματίες υγείας και εκπαίδευσης.
Παπαγεωργίου, Βάγια Α.
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source