Results 111 to 120 of about 2,175 (165)

Structural Insights into Neonicotinoids and N-Unsubstituted Metabolites on Human nAChRs by Molecular Docking, Dynamics Simulations, and Calcium Imaging. [PDF]

Int J Mol Sci, 2023
Grillberger K, Cöllen E, Trivisani CI, Blum J, Leist M, Ecker GF.   +5 more
europepmc   +1 more source

A deep learning framework (CreoPep) for target-specific design and optimization of conotoxin peptides. [PDF]

Commun Chem
Ge C, Tae HS, Lu L, Zhang Z, Huang Z, An B, Wang Y, Jiang T, Cai W, Chang S, Adams DJ, Yu R.   +11 more
europepmc   +1 more source

Coronaridine congeners decrease neuropathic pain in mice and inhibit α9α10 nicotinic acetylcholine receptors and CaV2.2 channels [PDF]

, 2020
Adams, D. J., Arias, H. R., Di Cesare Mannelli, L., Ghelardini, C., Micheli, L., Tae, H. -S., Yousuf, A.   +6 more
core   +1 more source

The Functional Topology of Phenylpiperazinium Agonists and Antagonists on the Nicotinic Acetylcholine Receptor Landscape: Pointing the Way for Future Therapeutic Management of Inflammation and Neuropathic Pain. [PDF]

ACS Chem Neurosci
Andleeb H, Gulsevin A, Papke RL.
europepmc   +1 more source

Molecular Determinants of Species Specificity of α-Conotoxin TxIB towards Rat and Human α6/α3β4 Nicotinic Acetylcholine Receptors. [PDF]

Int J Mol Sci, 2023
Xie T, Qin Y, Zhao J, Dong J, Qi P, Zhang P, Zhangsun D, Zhu X, Yu J, Luo S.   +9 more
europepmc   +1 more source

Structural insights into the progressive recovery of α7 nicotinic acetylcholine receptor from nicotine-induced desensitization. [PDF]

Sci Adv
Liu S, Chen H, Zhu X, Ye F, Zhao Y, Qin J, Zheng Y, Wang X, Zhang L, Chen H, Li X, Mu W, Fu Y, Luo C, Hou H, Bai C, Liu L, Tian C.   +17 more
europepmc   +1 more source

Chimeric Approach to Identify Molecular Determinants of Nicotinic Acetylcholine Receptors. [PDF]

Int J Mol Sci
Sapkota P, Akaberi SM, Ghimire B, Sharma K.   +3 more
europepmc   +1 more source

Molecular insights into the α6β4 nicotinic acetylcholine receptor function and ligand recognition. [PDF]

Nat Commun
Su J, Yu Z, Yin Z, Zhang Z, Zhao J, Meng Y, Li R, Gao Y, Zhang H, Yu R, Zhao Y.   +10 more
europepmc   +1 more source

The role of acetylcholine and its receptors in tumor immune regulation: mechanisms and potential therapeutic targets. [PDF]

Mol Cancer
Zhang C, Guo X, Wang Y, Zhang S, Wang Z.
europepmc   +1 more source

Understanding varenicline function via key receptor and ligand interactions.

Cell Rep Phys Sci
Aiken SG, Fiorito D, Harper M, Pikus G, Underhill J, Murray J, Rawlinson J, O'Donoghue AC, Gotti C, Lummis SCR, Minguez Viñas T, Viscarra F, Bermudez I, Gallagher T, Oliveira ASF.   +14 more
europepmc   +1 more source