Results 101 to 110 of about 18,354 (167)

An α7 nAChR approach for the baseline-dependent modulation of deviance detection in schizophrenia: A pilot study assessing the combined effect of CDP-choline and galantamine. [PDF]

J Psychopharmacol, 2023
Choueiry J, Blais CM, Shah D, Smith D, Fisher D, Labelle A, Knott V.   +6 more
europepmc   +1 more source

Nicotine activation of MAPK/ERK pathway in SH-SY5Y cells is mediated by α7 nAchR.

, 2015
We identified the effect of inhibition of α7 nAchRs expression by shRNA in Fig. 3. A, B) The effect of α7 shRNA by western blotting and real-time PCR. c) In the absence or presence of nicotine for 30 minutes, the EGR-1 and phosphorylated ERK1/2 levels ...
Fengguang Gao (713423), Liuwei Zhu (713420), Jie Zhang (64655), Zhiliang Qiao (713422), Guanghui Jin (323410), Qiqing Zhang (713424), Jinhua Qiu (620166), Maoqiang Xue (713419), Guicheng Du (713421)   +8 more
core   +1 more source

The Human-Restricted Isoform of the α7 nAChR, CHRFAM7A: A Double-Edged Sword in Neurological and Inflammatory Disorders. [PDF]

Int J Mol Sci, 2022
Di Lascio S, Fornasari D, Benfante R.
europepmc   +1 more source

Evaluating Commercially Available Antibodies for Rat α7 Nicotinic Acetylcholine Receptors

, 2017
Alpha7 nicotinic acetylcholine receptors (α7 nAChRs) are important drug targets in neurological disorders and inflammation, making their detection and localization by validated antibodies highly desirable.
Brijesh K. Garg, Ralph H. Loring
core   +1 more source

Development of ¹¹C-Labeled ASEM Analogues for the Detection of Neuronal Nicotinic Acetylcholine Receptors (α7-nAChR). [PDF]

ACS Chem Neurosci, 2022
Nag S, Miranda-Azpiazu P, Jia Z, Datta P, Arakawa R, Moein MM, Yang Z, Tu Y, Lemoine L, Ågren H, Nordberg A, Långström B, Halldin C.   +12 more
europepmc   +1 more source

α7 nAChR expression and GTS-21 stimulation do not block TNF-induced NFκB-mediated signaling in GH4C1 cells.

, 2019
(A) 125I-αBGT binding to WT GH4C1 cells compared to α7 nAChR transfected cells (α7). Concentrations and error bars are as described in methods. *** P< 0.0001 compared to WT.
Brijesh K. Garg (6556034), Ralph H. Loring (6556037)   +1 more
core   +1 more source

CHRFAM7A overexpression in human iPSC-derived Interneurons dysregulates α7- nAChR surface expression and alters response to oligomeric β-amyloid peptide

The α7 neuronal nicotinic receptor (α7-nAChR) gene, CHRNA7 , is widely expressed within the brain and at the periphery. It plays various important roles in cognition and immune functions.
Llach Pou, Maria, Cloëz-Tayarani, Isabelle, Maskos, Uwe, Pons, Stéphanie, Thiberge, Camille   +4 more
core   +1 more source

Labeling of β2 and α7 nAChR subunits in tissue resident macrophages in the stomach and ileum.

, 2013
Tissue resident macrophages were immunohistochemically labeled for F4/80 (red). A; Resident macrophages in stomach muscularis of a wild-type mouse were β2 nAChR-immunoreactive (green).
Pedro J. Gomez-Pinilla (478993), Michael Schemann (154153), Klaus Michel (478992), Andrea Nemethova (478991), Guy E. Boeckxstaens (421150)   +4 more
core   +1 more source

Efecto modulador de los glucocorticoides sobre la angiogénesis mediada por PI3K/Akt activada por α7-nAChR: Una revisión narrativa

ARS Medica
Introducción: los glucocorticoides (GC) han sido ampliamente utilizados en el tratamiento de patologías oculares debido a sus efectos antiinflamatorios y anti-angiogénicos.
Matías Latorre de Halleux, Bastián Hernández Vivanco, Paulina Carvajal Vidal, Magdalena Cortés Saavedra   +3 more
doaj   +1 more source

Extracellular Vesicles Derived from Metastatic Melanoma Cells Transfer α7-nAChR mRNA, Thus Increasing the Surface Expression of the Receptor and Stimulating the Growth of Normal Keratinocytes. [PDF]

Acta Naturae, 2022
Bychkov ML, Kirichenko AV, Mikhaylova IN, Paramonov AS, Kirpichnikov MP, Shulepko MA, Lyukmanova EN.   +6 more
europepmc   +1 more source