Results 51 to 60 of about 761,437 (260)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

EFFECTS OF HEATING TEMPERATURE AND β-CAROTENE ON QUALITY AND FATTY ACIDS COMPOSITION OF VEGETABLE OILS

open access: yesStudia Universitatis Babes-Bolyai Chemia, 2021
The purpose of the study was to investigate the effects of temperature and β-carotene addition on the quality parameters of corn and palm oils subjected to heating. Vegetable oils and 0.005% β-caroten additivated oils were heated at varying temperatures
Flavia POP, Crina PAȘCU
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Enantioselective decarboxylative chlorination of β-ketocarboxylic acids

open access: yesNature Communications, 2017
Due to the synthetic utility of the products, stereoselective halogenation is a powerful method for the synthesis of chiral compounds. Here the authors report an enantioselective decarboxylative chlorination, giving access to a range of α-chloroketones.
Kazutaka Shibatomi   +5 more
doaj   +1 more source

Bitter Substances in the Hop Lupulin

open access: yesAgricultural Science and Practice, 2014
Aim. To investigate the quantity and structure of α-, β-acids and xanthohumol in lupulin grains of different hop varieties that essentially differ in these biochemical indexes, and also the presence of the substances both in staminate racemes and in the ...
M. Liashenko   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The distribution of fatty acids between the α′- and β-positions of the glycerophospholipids of buttermilk

open access: yesJournal of Lipid Research, 1963
Fractionation of buttermilk phospholipids on silicic acid columns gave a cephalin (mixture of amino-N; phospholipids) fraction, in which approximately 29% of the total fatty acids were saturated, and phosphatidyl choline, in which approximately 57% of ...
J.C. Hawke
doaj   +1 more source

Correlation of secretory phospholipase-A2 activity and fatty acids in cerebrospinal fluid with liver enzymes tests [PDF]

open access: yesJournal of Analytical Research in Clinical Medicine, 2016
Introduction: The aim was to determine whether secretory phospholipase-A2 (sPLA2) activity and fatty acids in cerebrospinal fluid (CSF) are correlated with liver enzymes tests.
Sepideh Ghodoosifar   +5 more
doaj   +1 more source

Ethyl Acetate Extraction of Humulus Lupulus Compounds with Characterization by Gas Chromatography-Mass Spectrometry [PDF]

open access: yes, 2012
Hops are an essential ingredient in flavoring and preserving beer. Hops contain two main types of compounds: α-acids and β-acids, which are the essential oils.
Mann, Francis, Martin, Benjamin
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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