Results 71 to 80 of about 761,437 (260)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Food consumption among adolescents and biological and adiposity outcomes
HSJObjective: to investigate the association between macronutrient consumption and biological and adiposity indicators in adolescents. Methods: A total of 77 adolescents were evaluated in relation to anthropometric measurements, sexual maturation, body ...
Cristina Maria Mendes resende +7 more
doaj +1 more source
IMPROVING THE HOP UTILIZATION IN THE BEER BIOTECHNOLOGY [PDF]
, 2008 The rate of isomerization of alpha acids to iso-alpha acids (the bittering compounds in beer) was characterized over a representative pH, wort concentration, time boiling and temperature range during the boiling portion of the brewing process. Because of
Goina, Veronica +4 more
core +2 more sources
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Hops Βeta-Acid Extract Yields Feedlot Performance Similar to Rumensin [PDF]
, 2015 Hops (Humulus lupulus) have played an integral role in beer manufacturing and are widely known for their antimicrobial and preservative properties. α-acids of hops are extracted and utilized to enhance beer flavor, leaving residues largely composed of β ...
Alvarado, C. +4 more
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
AntioxidantsOxidative stress on the mitochondria in a human cell is attributed to several life-risking conditions, and as such, the importance of molecular structures packed with antioxidant properties and structural characteristics to enter the cell to help prevent
Christopher Sbarbaro +9 more
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Journal of Lipid Research, 1998 Studies with purified subcellular organelles from rat liver indicate that nervonic acid (C24:1) is β-oxidized preferentially in peroxisomes. Lack of effect by etomoxir, inhibitor of mitochondrial β-oxidation, on β-oxidation of lignoceric acid (C24:0), a ...
Rajat Sandhir +3 more
doaj +1 more source
Isonitrile-Based Multicomponent Synthesis of β-Amino Boronic Acids as β-Lactamase Inhibitors
Antibiotics, 2020 The application of various isonitrile-based multicomponent reactions to protected (2-oxoethyl)boronic acid (as the carbonyl component) is described. The Ugi reaction, both in the four components and in the four centers–three components versions, and the ...
Emanuele Bassini +7 more
doaj +1 more source