Results 61 to 70 of about 2,431,497 (250)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
, 2015 An l-erythro-3,5-diaminohexanoate dehydrogenase from Candidatus Cloacamonas acidaminovorans (3,5-DAHDHcca) was engineered to β-amino acid dehydrogenase (β-AADH) by screening a domain scanning mutagenesis library.
Dalong Zhang (164879) +5 more
core +1 more source
Nature Communicationsβ-Branched aromatic α-amino acids are valuable building blocks in natural products and pharmaceutically active compounds. However, their chemical or enzymatic synthesis is challenging due to the presence of two stereocenters.
Chenghai Sun +12 more
doaj +1 more source
Scientific Reports, 2022 Adult wasps primary food resource is larval saliva. This liquid secretion consists mainly of amino acids and carbohydrates processed from the prey brought to the colony by the foragers. However, adults also regularly consume floral nectar.
Sofia Bouchebti +4 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Highly functionalized cyclic and bicyclic β−amino acids from sugar β−nitroesters [PDF]
, 2019 The synthesis of highly functionalized bicyclic and cyclic β-amino acids from β-nitrosugars is reported. Specifically, our strategy for the synthesis of polyhydroxylated cyclopentane β-amino acids via the intramolecular C-alkylation of 6-nitro-2-O ...
Otero, JM +5 more
core +1 more source
Interactive effects of gallic/ferulic/caffeic acids and anthocyanins on pigment thermal stabilities
Data in Brief, 2017 The data presented in this article are related to the research article entitled “The effects of gallic/ferulic/caffeic acids on colour intensification and anthocyanin stability” (Qian et al., 2017) [1].
Bing-Jun Qian +4 more
doaj +1 more source
Isonitrile-Based Multicomponent Synthesis of β-Amino Boronic Acids as β-Lactamase Inhibitors
Antibiotics, 2020 The application of various isonitrile-based multicomponent reactions to protected (2-oxoethyl)boronic acid (as the carbonyl component) is described. The Ugi reaction, both in the four components and in the four centers–three components versions, and the ...
Emanuele Bassini +7 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, Volume 600, Issue 18, Page 2716-2728, September 2026.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Food consumption among adolescents and biological and adiposity outcomes
HSJObjective: to investigate the association between macronutrient consumption and biological and adiposity indicators in adolescents. Methods: A total of 77 adolescents were evaluated in relation to anthropometric measurements, sexual maturation, body ...
Cristina Maria Mendes resende +7 more
doaj +1 more source