Results 11 to 20 of about 2,121,152 (251)

β-Adrenergic receptor signaling in prostate cancer [PDF]

open access: yesFrontiers in Oncology, 2015
Enhanced sympathetic signaling, often associated with obesity and chronic stress, is increasingly acknowledged as a contributor to cancer aggressiveness.
Peder Rustøen Braadland   +4 more
doaj   +2 more sources

β-adrenergic receptor responsiveness in aging heart and clinical implications [PDF]

open access: yesFrontiers in Physiology, 2014
Elderly healthy individuals have a reduced exercise tolerance and a decreased left ventricle inotropic reserve related to increased vascular afterload, arterial-ventricular load mismatching, physical deconditioning and impaired autonomic regulation (the ...
Nicola eFerrara   +10 more
doaj   +2 more sources

Examining the suitability of molecular and metabolomic-based techniques as tools for assessing the effects of pharmaceuticals in the aquatic environment [PDF]

open access: yes, 2009
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Pharmaceuticals represent important and indispensable elements in modern society and their usage is considerable.
Eccles, Paul David
core   +7 more sources

Pharmaceuticals in the aquatic environment: β-blockers as a case study [PDF]

open access: yes, 2008
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 20/09/2008.The presence of many human pharmaceuticals in the aquatic environment is now a worldwide concern and yet little is known of the chronic effects ...
Giltrow, Emma
core   +7 more sources

Tailoring therapy for heart failure: the pharmacogenomics of adrenergic receptor signaling [PDF]

open access: yes, 2014
Grazia Daniela Femminella,1 Vincenzo Barrese,2,3 Nicola Ferrara,1,4 Giuseppe Rengo4 1Department of Translational Medical Sciences, Federico II University, Naples, Italy; 2Department of Neuroscience, Reproductive Science and Odontostomatology, Federico II
Ferrara, N   +11 more
core   +1 more source

Pharmacogenetics of ophthalmic topical β-blockers [PDF]

open access: yes, 2008
Glaucoma is the second leading cause of blindness worldwide. The primary glaucoma risk factor is elevated intraocular pressure. Topical β-blockers are affordable and widely used to lower intraocular pressure.
Smith, Edward M.   +4 more
core   +1 more source

"In vitro" study of the mode of action of antidepressants in cell culture models : comparison of the effects of "Hypericum perforatum L." extracts and classical synthetic compounds on the [beta]-adrenergic signal pathway [PDF]

open access: yes, 2005
The clinical effectiveness of the plant extract of Hypericum perforatum L. in treating mild to moderate depression is well established. The extract shows a more favourable side effect profile than other antidepressant drugs, like tricyclics and selective
Wirz, Adrian
core   +1 more source

Cardiac adrenergic control and atrial fibrillation [PDF]

open access: yes, 2010
Atrial fibrillation (AF) is the most common cardiac arrhythmia, and it causes substantial mortality. The autonomic nervous system, and particularly the adrenergic/cholinergic balance, has a profound influence on the occurrence of AF ...
Workman, A.J.
core   +1 more source

Gravin orchestrates protein kinase A and 2-adrenergic receptor signaling critical for synaptic plasticity and memory [PDF]

open access: yes, 2012
A kinase-anchoring proteins (AKAPs) organize compartmentalized pools of protein kinase A (PKA) to enable localized signaling events within neurons. However, it is unclear which of the many expressed AKAPs in neurons target PKA to signaling complexes ...
Huang, T.   +32 more
core   +1 more source

Noradrenaline Improves Behavioral Contrast Sensitivity via the β-Adrenergic Receptor. [PDF]

open access: yesPLoS ONE, 2016
Noradrenaline (NA) is released from the locus coeruleus in the brainstem to almost the whole brain depending on the physiological state or behavioral context.
Ryo Mizuyama   +3 more
doaj   +1 more source

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