Results 81 to 90 of about 35,803 (184)

Acute Modafinil Exposure Induces Neurobehavioral Alterations in Zebrafish: Implications for Off‐Label Cognitive Enhancement

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Modafinil (2‐(benzhydrylsulfinyl)acetamide) is a psychostimulant commonly prescribed for sleep disorders such as narcolepsy, excessive daytime sleepiness, and obstructive sleep apnea. Recently, its use has extended beyond clinical indications, with neurotypical individuals adopting it as a smart drug to enhance alertness and cognitive ...
Luciane Dellazari da Silva do Prado   +9 more
wiley   +1 more source

The regulatory frameworks surrounding CRISPR‐edited papaya and their impact on international commerce

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract The papaya tree (Carica papaya L.), native to the Americas, is cultivated in tropical regions and holds substantial economic importance, with an estimated export volume of 365 000 t in 2023. However, diseases caused by viruses, fungi, bacteria, and nematodes can lead to severe losses.
Luíza Favaratto   +7 more
wiley   +1 more source

Valorization of Zingiber officinale Roscoe leaf biomass: phytotoxic potential and chemical profiling toward sustainable weed management

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Zingiber officinale Roscoe is widely cultivated as a spice and functional food, generating substantial amounts of aerial biomass that is commonly discarded after harvest. Within a circular‐economy framework, this study investigated the phytotoxic potential of Z.
Sara Vitalini   +7 more
wiley   +1 more source

β‐Aminoisobutyric Acid Alleviates Cisplatin‐Induced Muscle Atrophy by Regulating E3 Ubiquitin Ligases, Apoptosis, Amino Acid Metabolism, Autophagy, and Ferroptosis

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Background Cisplatin (CIS) is a widely used broad‐spectrum anticancer agent, but its clinical application is often limited by severe adverse effects, including skeletal muscle atrophy, which compromises patients' quality of life and treatment efficacy.
Hao‐Zhe Wang   +10 more
wiley   +1 more source

Long-Lasting Defence Priming by β-Aminobutyric Acid in Tomato Is Marked by Genome-Wide Changes in DNA Methylation. [PDF]

open access: yesFront Plant Sci, 2022
Catoni M   +7 more
europepmc   +1 more source

Harnessing microbial power to degrade hydrocarbon‐based plastics

open access: yesmLife, EarlyView.
Abstract The growing global plastic waste crisis demands the development of urgent, effective, and sustainable solutions. While conventional recycling methods present intrinsic limitations, microbial biodegradation of plastic waste has emerged as a promising alternative.
Hui Li   +4 more
wiley   +1 more source

Fortification Technology and Quality Evaluation of β-Nicotinamide Mononucleotide in Fermented Coix Seed

open access: yesShipin gongye ke-ji
The aim of this study was to develop a fermented food rich in β-nicotinamide mononucleotide (β-NMN). The influence of fermentation strain, fermentation time, and addition of B-group vitamins on the β-NMN content of fermented Coix (Coix lacryma-jobi) seed
Caihua LIU   +6 more
doaj   +1 more source

Proteomic Profiling of Primary Hippocampal Neurons Reveals Noncanonical GFAP Expression and Metabolic Adaptations in Glia‐Free Culture

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Despite their widespread use as a research model, a comprehensive, quantitative proteomic profile of the cultured hippocampal neurons has remained unexplored. Here, we provide the first global proteomic characterization of primary murine hippocampal neurons cultured for 14 days under near‐physiological glucose conditions (2.5 mM).
Dominika Drulis‐Fajdasz   +6 more
wiley   +1 more source

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