Results 181 to 190 of about 886,342 (318)
, 2019 Table S1. Primers in this study (DOCX 18 kb) (DOCX 19 kb)
Wu, Jian +8 more
openaire +1 more source
PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression
Advanced Science, EarlyView.Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian +13 more
wiley +1 more source
, 2019 Additional file 1: Table S1. Association of MET and RUNX3 expression with clinicopathological characteristics in 34 gastric cancer patients. Table S2. List of oligonucleotides for real-time PCR. Table S3. List of antibodies and its characteristic.
Sohn, Sung-Hwa +8 more
openaire +1 more source
CCL3 and IL‐7 Synergistically Enhance CAR‐T Efficacy in Solid Tumors
Advanced Science, EarlyView.Synergistic delivery of CCL3 and IL‐7 by CAR‐T cells overcomes the immunosuppressive tumor microenvironment by enhancing cell infiltration, survival, and local immune reprogramming. This also establishes positive feedback that amplifies anti‐tumor activity and memory responses in both CAR‐T and endogenous T cells, presenting a robust therapeutic ...
Huanpeng Chen +12 more
wiley +1 more source
Role and regulation of miR-483 in cancer
, 2012 The hsa-mir-483 locus is located at chromosome 11p15.5 within intron 2 of the IGF2 locus. Because of its location, de-regulated in Wilms’ tumor and other neoplasia, I hypothesized that this microRNA had a potential role in tumors.
Veronese, Angelo
core
Advanced Science, EarlyView.A brain‐targeted nanoparticle enables delivery of a therapeutic nanobody (Nb.29E9) that inhibits pathogenic GSK3β signaling. This intervention restores AMPK/mTORC1/TGFβ homeostasis, attenuates neuroinflammation and oxidative stress, and promotes long‐term functional recovery after ischemic stroke.
Lan Li +14 more
wiley +1 more source
β-catenin-driven endomesoderm specification is a Bilateria-specific novelty
Nature CommunicationsEndomesoderm specification by a maternal β-catenin signal and body axis patterning by interpreting a gradient of zygotic Wnt/β-catenin signalling was suggested to predate the split between Bilateria and their sister clade Cnidaria.
Tatiana Lebedeva +8 more
doaj +1 more source
Advanced Science, EarlyView.Therapeutic role and mechanism of human urine stem cells (hUSCs) in pulmonary fibrosis. hUSCs alleviated pulmonary fibrosis by selectively inhibiting macrophage‐myofibroblast transition (MMT) in two ways: on one hand, hUSCs inhibited mitochondrial reactive oxygen species (mtROS) production and apoptosis/senescence of epithelial cells in pulmonary ...
Zhou‐Hang Zhang +10 more
wiley +1 more source
An immunohistochemical study of beta-catenin in HNPCC colon tumours
, 2004 Includes bibliographical references (leaves 49-55).Beta-catenin is normally complexed with adenomatous polyposis coli (APC) protein and E-cadherin adhesion molecule, and localized on the cell membrane.
Watkins, Jennifer G
core
The Regulation of β-catenin signalling by α-catenin [PDF]
, 2001 Alpha-catenin and β-catenin link cadherins to the cytoskeleton at sites of cell-cell contact. Beta-catenin also associates with Tcf/Lef-1 transcription factors, activating transcription of genes encoding proteins involved in cell cycle regulation and ...
Giannini, Ana Lucia Moraes
core