Results 291 to 300 of about 886,342 (318)

Pilose Antler Protein Extract Alleviates Osteoporosis and Is Associated with Activation of the Wnt/β-Catenin Signaling Pathway. [PDF]

Pharmaceuticals (Basel)
Gong J, Ma Y, Huang J, Yang W, Wang Y, Sun Y.   +5 more
europepmc   +1 more source

Correction to 'The Natural Agent Rhein Induces β-catenin Degradation and Tumour Growth Arrest'. [PDF]

J Cell Mol Med
europepmc   +1 more source

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Design and synthesis of selective inhibitors for β-catenin/t-cell factor-4 protein-protein interaction

2018
Selective disruption of protein-protein interactions by small molecules is important for probing the structure and dynamic aspects of the cellular network. It can also provide new therapeutic targets. β-Catenin of the canonical Wnt signaling pathway uses the same positively charged groove to bind with T-cell factor (Tcf), cadherin, and adenomatous ...
openaire   +1 more source

Toward better development of protein-protein interaction inhibitors: applications to the β-catenin/t-cell factor protein-protein interaction

2018
The dysregulation of proteinâ€"protein interaction (PPI) networks has been implicated in many diseases. Designing therapeutic small-molecule inhibitors of these interactions is a challenging field for medicinal chemistry. This work advances the techniques for discovering more potent PPI inhibitors through integration of computational and biochemical ...
openaire   +1 more source

Intestinal Crypt Fission and Expression of Î'-Catenin in the Small Intestine of Humans

Gastroenterology, 2017
Zenab M. Dudhwala, Gordon S. Howarth, Paul Drew, David Moore, Adrian G. Cummins   +4 more
openaire   +1 more source

Direct targeting of β‐catenin in the Wnt signaling pathway: Current progress and perspectives

Medicinal Research Reviews, 2021
Zhen Wang, Haitao Ji
exaly  

Signal transduction by β-catenin

Current Opinion in Cell Biology, 1995
openaire   +1 more source

Dual-specificity RNA aptamers enable manipulation of target-specific O-GlcNAcylation and unveil functions of O-GlcNAc on β-catenin

Cell, 2023
Yi Zhu, Gerald W Hart
exaly  

Wnt/β-catenin signaling and kidney fibrosis

Kidney International Supplements, 2014
Roderick J Tan, Dong Zhou, Lili Zhou
exaly