Results 271 to 280 of about 1,062,506 (300)

Traditional Chinese medicine interventions targeting Wnt/β-catenin signaling in cerebral ischemia/reperfusion injury: a review. [PDF]

Front Pharmacol
Wu Y, Sun Y, Song Y, Wang X.
europepmc   +1 more source

C1orf226 Promotes Glioma Stemness and Oncogenesis in Glioma via PLK1-Mediated Wnt/β-Catenin Signaling. [PDF]

Cancer Med
Lu Y, Jiang C, Wu H, Shang J, Wang B, Cang S, Zhang J.   +6 more
europepmc   +1 more source

ZNF695 Promotes Colorectal Cancer Progression Through Transcriptional Activation of CBX8 and Subsequent Wnt/β-Catenin Signaling Activation. [PDF]

Mol Carcinog
Tang X, Ke H, Huang Y.
europepmc   +1 more source

SPARC Promotes Corneal Epithelial Wound Healing Through β-catenin Nuclear Translocation and c-Met Activation. [PDF]

Invest Ophthalmol Vis Sci
Zhang M, Yang D, Wang L, Li X, Zheng C, Liu J, Shen L, Cui Y, Zhu J.   +8 more
europepmc   +1 more source

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Design and synthesis of selective inhibitors for β-catenin/t-cell factor-4 protein-protein interaction

2018
Selective disruption of protein-protein interactions by small molecules is important for probing the structure and dynamic aspects of the cellular network. It can also provide new therapeutic targets. β-Catenin of the canonical Wnt signaling pathway uses the same positively charged groove to bind with T-cell factor (Tcf), cadherin, and adenomatous ...
openaire   +1 more source

Toward better development of protein-protein interaction inhibitors: applications to the β-catenin/t-cell factor protein-protein interaction

2018
The dysregulation of proteinâ€"protein interaction (PPI) networks has been implicated in many diseases. Designing therapeutic small-molecule inhibitors of these interactions is a challenging field for medicinal chemistry. This work advances the techniques for discovering more potent PPI inhibitors through integration of computational and biochemical ...
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Intestinal Crypt Fission and Expression of Î'-Catenin in the Small Intestine of Humans

Gastroenterology, 2017
Zenab M. Dudhwala, Gordon S. Howarth, Paul Drew, David Moore, Adrian G. Cummins   +4 more
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Direct targeting of β‐catenin in the Wnt signaling pathway: Current progress and perspectives

Medicinal Research Reviews, 2021
Haitao Ji, Zhen Wang
exaly  

Signal transduction by β-catenin

Current Opinion in Cell Biology, 1995
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